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PDB: 483 results

8HVR
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BU of 8hvr by Molmil
Cryo-EM structure of AfsR-dependent transcription activation complex with afsS promoter
Descriptor: DNA (65-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Wang, Y, Zheng, J.
Deposit date:2022-12-27
Release date:2023-12-27
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Structural and functional characterization of AfsR, an SARP family transcriptional activator of antibiotic biosynthesis in Streptomyces.
Plos Biol., 22, 2024
1KTM
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BU of 1ktm by Molmil
SOLUTION STRUCTURE OF FAT DOMAIN OF FOCAL ADHESION KINASE
Descriptor: FOCAL ADHESION KINASE 1
Authors:Liu, G, Guibao, C, Zheng, J.
Deposit date:2002-01-16
Release date:2003-01-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural Insight into the Mechanisms of Targeting and Signaling of Focal Adhesion Kinase
Mol.Cell.Biol., 22, 2002
5BNO
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BU of 5bno by Molmil
Crystal structure of human enterovirus D68 in complex with 6'SLN
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Liu, Y, Sheng, J, Meng, G, Xiao, C, Rossmann, M.G.
Deposit date:2015-05-26
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Sialic acid-dependent cell entry of human enterovirus D68.
Nat Commun, 6, 2015
5BNN
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BU of 5bnn by Molmil
Crystal structure of human enterovirus D68 in complex with 6'SL
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Liu, Y, Sheng, J, Meng, G, Xiao, C, Rossmann, M.G.
Deposit date:2015-05-26
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Sialic acid-dependent cell entry of human enterovirus D68.
Nat Commun, 6, 2015
7Y6E
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BU of 7y6e by Molmil
Crystal structure of sDscam FNIII23 domains, isoform Beta2v6
Descriptor: Dscam
Authors:Chen, Q, Yu, Y, Cheng, J.
Deposit date:2022-06-20
Release date:2023-05-24
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.034 Å)
Cite:Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y8I
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BU of 7y8i by Molmil
Crystal structure of sDscam FNIII3 domain, isoform alpha7
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Dscam, ...
Authors:Chen, Q, Yu, Y, Cheng, J.
Deposit date:2022-06-24
Release date:2023-05-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y95
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BU of 7y95 by Molmil
Crystal structure of sDscam Ig1 domain, isoform beta6v2
Descriptor: Dscam, GLYCEROL, SODIUM ION
Authors:Chen, Q, Yu, Y, Cheng, J.
Deposit date:2022-06-24
Release date:2023-05-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
6J0U
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BU of 6j0u by Molmil
Crystal Structure of the acyltransferase domain from the third module of the ansamitocin polyketide synthase
Descriptor: PHOSPHATE ION, Type 1 modular polyketide synthase
Authors:Zhang, F, Zheng, J.
Deposit date:2018-12-26
Release date:2019-12-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural and Biochemical Insight into the Recruitment of Acyl Carrier Protein-Linked Extender Units in Ansamitocin Biosynthesis.
Chembiochem, 21, 2020
5XWW
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BU of 5xww by Molmil
Substrate-bound Structure of G355T/Q364H mutant of a Ketoreductase from amphotericin Polyketide Synthases
Descriptor: AmphB, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, S-[2-[3-[[(2R)-3,3-dimethyl-2,4-bis(oxidanyl)butanoyl]amino]propanoylamino]ethyl] (2R)-2-methyl-3-oxidanylidene-pentanethioate
Authors:Liu, C, Zheng, J.
Deposit date:2017-06-30
Release date:2018-06-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Substrate-bound structures of a ketoreductase from amphotericin modular polyketide synthase.
J. Struct. Biol., 203, 2018
5XWV
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BU of 5xwv by Molmil
Substrate-bound Structure of a Ketoreductase from the Second Module of the amphotericin Polyketide Synthases
Descriptor: AmphB, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, S-[2-[3-[[(2R)-3,3-dimethyl-2,4-bis(oxidanyl)butanoyl]amino]propanoylamino]ethyl] (2R)-2-methyl-3-oxidanylidene-pentanethioate
Authors:Liu, C, Zheng, J.
Deposit date:2017-06-30
Release date:2018-06-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Substrate-bound structures of a ketoreductase from amphotericin modular polyketide synthase.
J. Struct. Biol., 203, 2018
8JPU
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BU of 8jpu by Molmil
Crystal Structure of the acyltransferase domain from the fifth module of the tylosin polyketide synthase
Descriptor: SULFATE ION, Tylactone synthase modules 4 & 5
Authors:Huang, S, Zheng, J.
Deposit date:2023-06-12
Release date:2024-06-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insights into the Substrate Specificity of Acyltransferases from Tylosin Polyketide Synthase and Spinosad Polyketide Synthase
To Be Published
5D9Y
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BU of 5d9y by Molmil
Crystal structure of TET2-5fC complex
Descriptor: DNA (5'-D(*AP*CP*TP*GP*TP*(5FC)P*GP*AP*AP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*TP*TP*CP*GP*AP*CP*AP*GP*T)-3'), FE (III) ION, ...
Authors:Hu, L, Cheng, J, Rao, Q, Li, Z, Li, J, Xu, Y.
Deposit date:2015-08-19
Release date:2015-11-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.971 Å)
Cite:Structural insight into substrate preference for TET-mediated oxidation.
Nature, 527, 2015
5DEU
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BU of 5deu by Molmil
Crystal structure of TET2-5hmC complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, DNA (5'-D(*AP*CP*CP*AP*CP*(5HC)P*GP*GP*TP*GP*GP*T)-3'), ...
Authors:Hu, L, Cheng, J, Rao, Q, Li, Z, Li, J, Xu, Y.
Deposit date:2015-08-26
Release date:2015-11-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structural insight into substrate preference for TET-mediated oxidation.
Nature, 527, 2015
5ZMZ
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BU of 5zmz by Molmil
Amyloid core of RIP1
Descriptor: Amyloid core of RIP1
Authors:Li, J.X, Zheng, J.
Deposit date:2018-04-06
Release date:2019-04-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Amyloid core of RIP1
To Be Published
5BNP
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BU of 5bnp by Molmil
Crystal structure of human enterovirus D68 in complex with 3'SLN
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Liu, Y, Sheng, J, Meng, G, Xiao, C, Rossmann, M.G.
Deposit date:2015-05-26
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Sialic acid-dependent cell entry of human enterovirus D68.
Nat Commun, 6, 2015
6KJ7
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BU of 6kj7 by Molmil
E. coli ATCase catalytic subunit mutant - G166P
Descriptor: Aspartate carbamoyltransferase catalytic subunit
Authors:Lei, Z, Zheng, J, Jia, Z.
Deposit date:2019-07-21
Release date:2020-03-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.839 Å)
Cite:New regulatory mechanism-based inhibitors of aspartate transcarbamoylase for potential anticancer drug development.
Febs J., 287, 2020
6K5L
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BU of 6k5l by Molmil
The crystal structure of isocitrate dehydrogenase kinase/phosphatase wtih two Mn2+ from E. coli
Descriptor: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase kinase/phosphatase, ...
Authors:Zhang, X, Lei, Z, Zheng, J, Jia, Z.
Deposit date:2019-05-29
Release date:2019-07-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Characterization of metal binding of bifunctional kinase/phosphatase AceK and implication in activity modulation.
Sci Rep, 9, 2019
6CKV
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BU of 6ckv by Molmil
Solution NMR structure of human BOK
Descriptor: Bcl-2-related ovarian killer protein
Authors:Grace, C.R, Zheng, J, Moldoveanu, T.
Deposit date:2018-03-01
Release date:2018-05-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Intrinsic Instability of BOK Enables Membrane Permeabilization in Apoptosis.
Cell Rep, 23, 2018
6J0M
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BU of 6j0m by Molmil
Cryo-EM Structure of an Extracellular Contractile Injection System, PVC baseplate in extended state (reconstructed with C3 symmetry)
Descriptor: Pvc8
Authors:Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N.
Deposit date:2018-12-24
Release date:2019-04-10
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
6KJB
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BU of 6kjb by Molmil
wild-type apo-form E. coli ATCase holoenzyme with an unusual open conformation of R167
Descriptor: Aspartate carbamoyltransferase catalytic subunit, Aspartate carbamoyltransferase regulatory chain, ZINC ION
Authors:Wang, N, Lei, Z, Zheng, J, Jia, Z.C.
Deposit date:2019-07-22
Release date:2020-06-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Conformational Plasticity of the Active Site Entrance inE. coliAspartate Transcarbamoylase and Its Implication in Feedback Regulation.
Int J Mol Sci, 21, 2020
2L6H
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BU of 2l6h by Molmil
Fat domain of focal adhesion kinase tethered to LD4 motif of paxillin via GGS linker
Descriptor: Focal adhesion kinase 1, linker, Paxillin
Authors:Bertolucci, C.M, Guibao, C, Zhang, C, Zheng, J.
Deposit date:2010-11-19
Release date:2012-05-30
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Fat Domain of Focal Adhesion Kinase Tethered to Ld4 Motif of Paxillin via GGS Linker
To be Published
2L6F
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BU of 2l6f by Molmil
NMR Solution structure of FAT domain of FAK complexed with LD2 and LD4 motifs of PAXILLIN
Descriptor: Focal adhesion kinase 1, linker1, Paxillin, ...
Authors:Bertolucci, C.M, Guibao, C, Zhang, C, Zheng, J.
Deposit date:2010-11-19
Release date:2012-05-30
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:NMR Solution Structure of Fat Domain of Fak Complexed with Ld2 and Ld4 Motifs of Paxillin
To be Published
6LT0
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BU of 6lt0 by Molmil
cryo-EM structure of C9ORF72-SMCR8-WDR41
Descriptor: Guanine nucleotide exchange C9orf72, Guanine nucleotide exchange protein SMCR8, WD repeat-containing protein 41
Authors:Tang, D, Sheng, J, Xu, L, Zhan, X, Yan, C, Qi, S.
Deposit date:2020-01-21
Release date:2020-04-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of C9ORF72-SMCR8-WDR41 reveals the role as a GAP for Rab8a and Rab11a.
Proc.Natl.Acad.Sci.USA, 117, 2020
7VX0
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BU of 7vx0 by Molmil
The structure of GdmN complex with ATP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, FE (III) ION, ...
Authors:Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L.
Deposit date:2021-11-12
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
Nat Commun, 13, 2022
3J8D
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BU of 3j8d by Molmil
Cryoelectron microscopy of dengue-Fab E104 complex at pH 5.5
Descriptor: Envelope protein E, antibody E111 Fab fragment, glycoprotein DIII
Authors:Zhang, X.Z, Sheng, J, Austin, S.K, Hoornweg, T, Smit, J.M, Kuhn, R.J, Diamond, M.S, Rossmann, M.G.
Deposit date:2014-10-13
Release date:2014-11-12
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (26 Å)
Cite:Structure of Acidic pH Dengue Virus Showing the Fusogenic Glycoprotein Trimers.
J.Virol., 89, 2015

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