6KJ7

E. coli ATCase catalytic subunit mutant - G166P

Summary for 6KJ7

Entry DOI	10.2210/pdb6kj7/pdb
Descriptor	Aspartate carbamoyltransferase catalytic subunit (2 entities in total)
Functional Keywords	aspartate transcarbamoylase catalytic subunit, de novo pyrimidine biosynthesis, transferase
Biological source	Escherichia coli K-12
Total number of polymer chains	1
Total formula weight	34377.17
Authors	Lei, Z.,Zheng, J.,Jia, Z. (deposition date: 2019-07-21, release date: 2020-03-18, Last modification date: 2023-11-22)
Primary citation	Lei, Z.,Wang, B.,Lu, Z.,Wang, N.,Tan, H.,Zheng, J.,Jia, Z. New regulatory mechanism-based inhibitors of aspartate transcarbamoylase for potential anticancer drug development. Febs J., 287:3579-3599, 2020 Cited by PubMed: 31967710 DOI: 10.1111/febs.15220 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.839 Å)

Structure validation