5L2T
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![BU of 5l2t by Molmil](/molmil-images/mine/5l2t) | The X-ray co-crystal structure of human CDK6 and Ribociclib. | Descriptor: | 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide, Cyclin-dependent kinase 6 | Authors: | Chen, P, Ferre, R.A, Deihl, W, Yu, X, He, Y.-A. | Deposit date: | 2016-08-02 | Release date: | 2016-08-24 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance. Mol.Cancer Ther., 15, 2016
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3VU6
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![BU of 3vu6 by Molmil](/molmil-images/mine/3vu6) | Short peptide HIV entry inhibitor MT-SC22EK with a M-T hook | Descriptor: | MTSC22, SULFATE ION, Transmembrane protein gp41 | Authors: | Yao, X, Chong, H.H, Waltersperger, S, Wang, M.T, He, Y.X, Cui, S. | Deposit date: | 2012-06-19 | Release date: | 2012-12-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.324 Å) | Cite: | Short-peptide fusion inhibitors with high potency against wild-type and enfuvirtide-resistant HIV-1 Faseb J., 27, 2013
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3ERF
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![BU of 3erf by Molmil](/molmil-images/mine/3erf) | Crystal structure of Gtt2 from Saccharomyces cerevisiae | Descriptor: | Glutathione S-transferase 2 | Authors: | Ma, X.X, Jiang, Y.L, He, Y.X, Chen, Y.X, Zhou, C.Z. | Deposit date: | 2008-10-02 | Release date: | 2009-10-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Structures of yeast glutathione-S-transferase Gtt2 reveal a new catalytic type of GST family. Embo Rep., 10, 2009
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7PFN
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![BU of 7pfn by Molmil](/molmil-images/mine/7pfn) | |
7PEH
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![BU of 7peh by Molmil](/molmil-images/mine/7peh) | Crystal Structure of a Class D Carbapenemase | Descriptor: | 1-BUTANOL, Beta-lactamase | Authors: | Zhou, Q, He, Y, Jin, Y. | Deposit date: | 2021-08-10 | Release date: | 2022-08-24 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity Acs Cent.Sci., 2023
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7PGO
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![BU of 7pgo by Molmil](/molmil-images/mine/7pgo) | Crystal Structure of a Class D Carbapenemase_R250A | Descriptor: | 1-BUTANOL, BROMIDE ION, Beta-lactamase | Authors: | Zhou, Q, He, Y, Jin, Y. | Deposit date: | 2021-08-15 | Release date: | 2022-08-24 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity Acs Cent.Sci., 2023
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7PEI
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![BU of 7pei by Molmil](/molmil-images/mine/7pei) | |
7PEP
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![BU of 7pep by Molmil](/molmil-images/mine/7pep) | Crystal Structure of a Class D Carbapenemase Complexed with Hydrolyzed Imipenem | Descriptor: | (2R,4S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-[(2-{[(Z)-iminomethyl]amino}ethyl)sulfanyl]-3,4-dihydro-2H-pyrrole-5-ca rboxylic acid, 1-BUTANOL, BROMIDE ION, ... | Authors: | Zhou, Q, He, Y, Jin, Y. | Deposit date: | 2021-08-11 | Release date: | 2022-08-24 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity Acs Cent.Sci., 2023
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7PSF
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7PSE
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![BU of 7pse by Molmil](/molmil-images/mine/7pse) | Crystal Structure of a Class D Carbapenemase_K73ALY Complexed with Oxacillin | Descriptor: | (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid, 1-BUTANOL, Beta-lactamase, ... | Authors: | Zhou, Q, He, Y, Jin, Y. | Deposit date: | 2021-09-23 | Release date: | 2022-10-05 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity Acs Cent.Sci., 2023
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3FYH
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![BU of 3fyh by Molmil](/molmil-images/mine/3fyh) | Recombinase in complex with ADP and metatungstate | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA repair and recombination protein radA, MAGNESIUM ION, ... | Authors: | Li, Y, He, Y, Luo, Y. | Deposit date: | 2009-01-22 | Release date: | 2009-09-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of an archaeal Rad51 homologue in complex with a metatungstate inhibitor. Biochemistry, 48, 2009
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7KJS
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![BU of 7kjs by Molmil](/molmil-images/mine/7kjs) | Crystal structure of CDK2/cyclin E in complex with PF-06873600 | Descriptor: | 6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-{[1-(methylsulfonyl)piperidin-4-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, Cyclin-dependent kinase 2, G1/S-specific cyclin-E1 | Authors: | McTigue, M.A, He, Y, Ferre, R.A. | Deposit date: | 2020-10-26 | Release date: | 2021-06-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.187 Å) | Cite: | Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer. J.Med.Chem., 64, 2021
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5W0P
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![BU of 5w0p by Molmil](/molmil-images/mine/5w0p) | Crystal structure of rhodopsin bound to visual arrestin determined by X-ray free electron laser | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endolysin,Rhodopsin,S-arrestin | Authors: | Zhou, X.E, He, Y, de Waal, P.W, Gao, X, Kang, Y, Van Eps, N, Yin, Y, Pal, K, Goswami, D, White, T.A, Barty, A, Latorraca, N.R, Chapman, H.N, Hubbell, W.L, Dror, R.O, Stevens, R.C, Cherezov, V, Gurevich, V.V, Griffin, P.R, Ernst, O.P, Melcher, K, Xu, H.E. | Deposit date: | 2017-05-31 | Release date: | 2017-08-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.013 Å) | Cite: | Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors. Cell, 170, 2017
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3ETL
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![BU of 3etl by Molmil](/molmil-images/mine/3etl) | RadA recombinase from Methanococcus maripaludis in complex with AMPPNP | Descriptor: | DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Li, Y, He, Y, Luo, Y. | Deposit date: | 2008-10-08 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis. Acta Crystallogr.,Sect.D, 65, 2009
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3ERG
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![BU of 3erg by Molmil](/molmil-images/mine/3erg) | Crystal structure of Gtt2 from Saccharomyces cerevisiae in complex with glutathione sulfnate | Descriptor: | GLUTATHIONE SULFONIC ACID, Glutathione S-transferase 2 | Authors: | Ma, X.X, Jiang, Y.L, He, Y.X, Chen, Y.X, Zhou, C.Z. | Deposit date: | 2008-10-02 | Release date: | 2009-10-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of yeast glutathione-S-transferase Gtt2 reveal a new catalytic type of GST family. Embo Rep., 10, 2009
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6VAG
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![BU of 6vag by Molmil](/molmil-images/mine/6vag) | Crystal structure of the oligomerization domain of phosphoprotein from parainfluenza virus 5 | Descriptor: | GLYCEROL, Phosphoprotein | Authors: | Aggarwal, M, Abdella, R, He, Y, Lamb, R.A. | Deposit date: | 2019-12-17 | Release date: | 2020-02-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure of a paramyxovirus polymerase complex reveals a unique methyltransferase-CTD conformation. Proc.Natl.Acad.Sci.USA, 117, 2020
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3EW9
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![BU of 3ew9 by Molmil](/molmil-images/mine/3ew9) | RADA recombinase from METHANOCOCCUS MARIPALUDIS in complex with AMPPNP and potassium ions | Descriptor: | DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Li, Y, He, Y, Luo, Y. | Deposit date: | 2008-10-14 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis. Acta Crystallogr.,Sect.D, 65, 2009
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7TRD
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![BU of 7trd by Molmil](/molmil-images/mine/7trd) | Human telomerase catalytic core structure at 3.3 Angstrom | Descriptor: | Telomerase RNA, partial sequence, Telomerase reverse transcriptase, ... | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-01-28 | Release date: | 2022-04-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
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7TRF
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![BU of 7trf by Molmil](/molmil-images/mine/7trf) | Human telomerase catalytic core RNP with H2A/H2B | Descriptor: | Histone H2A, Histone H2B type 1-C/E/F/G/I, Telomerase RNA, ... | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-01-28 | Release date: | 2022-04-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
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7TRE
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![BU of 7tre by Molmil](/molmil-images/mine/7tre) | Human telomerase catalytic core with shelterin protein TPP1 | Descriptor: | Adrenocortical dysplasia protein homolog, Telomerase RNA, partial sequence, ... | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-01-28 | Release date: | 2022-04-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
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7TRC
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![BU of 7trc by Molmil](/molmil-images/mine/7trc) | Human telomerase H/ACA RNP at 3.3 Angstrom | Descriptor: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-01-28 | Release date: | 2022-04-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
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1JNB
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![BU of 1jnb by Molmil](/molmil-images/mine/1jnb) | CONNECTOR PROTEIN FROM BACTERIOPHAGE PHI29 | Descriptor: | UPPER COLLAR PROTEIN | Authors: | Simpson, A.A, Leiman, P.G, Tao, Y, He, Y, Badasso, M.O, Jardine, P.J, Anderson, D.L, Rossmann, M.G. | Deposit date: | 2001-07-23 | Release date: | 2001-08-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure determination of the head-tail connector of bacteriophage phi29. Acta Crystallogr.,Sect.D, 57, 2001
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3EWA
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![BU of 3ewa by Molmil](/molmil-images/mine/3ewa) | RADA recombinase from METHANOCOCCUS MARIPALUDIS in complex with AMPPNP and ammonium ions | Descriptor: | DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Li, Y, He, Y, Luo, Y. | Deposit date: | 2008-10-14 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis. Acta Crystallogr.,Sect.D, 65, 2009
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5W5Y
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![BU of 5w5y by Molmil](/molmil-images/mine/5w5y) | RNA polymerase I Initial Transcribing Complex | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Han, Y, He, Y. | Deposit date: | 2017-06-16 | Release date: | 2017-07-26 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural mechanism of ATP-independent transcription initiation by RNA polymerase I. Elife, 6, 2017
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5W66
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![BU of 5w66 by Molmil](/molmil-images/mine/5w66) | RNA polymerase I Initial Transcribing Complex State 3 | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Han, Y, He, Y. | Deposit date: | 2017-06-16 | Release date: | 2017-07-26 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural mechanism of ATP-independent transcription initiation by RNA polymerase I. Elife, 6, 2017
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