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PDB: 106 件

2HLW
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Solution Structure of the Human Ubiquitin-conjugating Enzyme Variant Uev1a
分子名称: Ubiquitin-conjugating enzyme E2 variant 1
著者Hau, D.D, Lewis, M.J, Saltibus, L.F, Pastushok, L, Xiao, W, Spyracopoulos, L.
登録日2006-07-10
公開日2006-09-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure and interactions of the ubiquitin-conjugating enzyme variant human uev1a: implications for enzymatic synthesis of polyubiquitin chains(,).
Biochemistry, 45, 2006
3ZDV
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Crystal structure of the LecB lectin from Pseudomonas aeruginosa in complex with Methyl 6-(2,4,6-trimethylphenylsulfonylamido)-6-deoxy-alpha-D-mannopyranoside
分子名称: 1,2-ETHANEDIOL, 2,4,6-trimethylbenzenesulfonamide, CALCIUM ION, ...
著者Hauck, D, Joachim, I, Frommeyer, B, Varrot, A, Philipp, B, MOller, H.M, Imberty, A, Exner, T.E, Titz, A.
登録日2012-11-30
公開日2013-09-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Discovery of Two Classes of Potent Glycomimetic Inhibitors of Pseudomonas Aeruginosa Lecb with Distinct Binding Modes.
Acs Chem.Biol., 8, 2013
5NR6
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NMR structure and 1H, 13C and 15N signal assignments for Dictyostelium discoidans MATB protein S71A mutant
分子名称: MatB protein
著者Neuhaus, D, Hedgethorne, K, Yang, J.-C.
登録日2017-04-22
公開日2017-09-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Homeodomain-like DNA binding proteins control the haploid-to-diploid transition in Dictyostelium.
Sci Adv, 3, 2017
5NR5
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NMR structure and 1H, 13C and 15N signal assignments for Dictyostelium discoideum MATA protein
分子名称: MatA protein
著者Neuhaus, D, Hedgethorne, K, Yang, J.-C.
登録日2017-04-22
公開日2017-09-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Homeodomain-like DNA binding proteins control the haploid-to-diploid transition in Dictyostelium.
Sci Adv, 3, 2017
1ZFD
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SWI5 ZINC FINGER DOMAIN 2, NMR, 45 STRUCTURES
分子名称: SWI5, ZINC ION
著者Neuhaus, D, Nakaseko, Y, Schwabe, J.W.R, Rhodes, D, Klug, A.
登録日1996-04-04
公開日1996-10-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structures of two zinc-finger domains from SWI5 obtained using two-dimensional 1H nuclear magnetic resonance spectroscopy. A zinc-finger structure with a third strand of beta-sheet.
J.Mol.Biol., 228, 1992
1Q1P
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E-Cadherin activation
分子名称: CALCIUM ION, Epithelial-cadherin
著者Haussinger, D, Stetefeld, J.
登録日2003-07-22
公開日2004-04-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Proteolytic E-cadherin activation followed by solution NMR and X-ray crystallography.
Embo J., 23, 2004
2KQD
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First PBZ domain of human APLF protein in complex with ribofuranosyladenosine
分子名称: ADENOSINE, Aprataxin and PNK-like factor, ZINC ION, ...
著者Neuhaus, D, Eustermann, S, Brockmann, C, Yang, J.
登録日2009-11-04
公開日2010-01-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).
Nat.Struct.Mol.Biol., 17, 2010
2KQE
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Second PBZ domain of human APLF protein in complex with ribofuranosyladenosine
分子名称: ADENOSINE, Aprataxin and PNK-like factor, ZINC ION, ...
著者Neuhaus, D, Eustermann, S, Brockmann, C, Yang, J.
登録日2009-11-04
公開日2010-01-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).
Nat.Struct.Mol.Biol., 17, 2010
2L30
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Human PARP-1 zinc finger 1
分子名称: Poly [ADP-ribose] polymerase 1, ZINC ION
著者Neuhaus, D, Eustermann, S, Yang, J, Videler, H.
登録日2010-08-30
公開日2011-02-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger.
J.Mol.Biol., 407, 2011
2LD1
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Structures and chemical shift assignments for the ADD domain of the ATRX protein
分子名称: Transcriptional regulator ATRX, ZINC ION
著者Neuhaus, D, Yang, J.
登録日2011-05-13
公開日2011-06-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural consequences of disease-causing mutations in the ATRX-DNMT3-DNMT3L (ADD) domain of the chromatin-associated protein ATRX.
Proc.Natl.Acad.Sci.USA, 104, 2007
2L31
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Human PARP-1 zinc finger 2
分子名称: Poly [ADP-ribose] polymerase 1, ZINC ION
著者Neuhaus, D, Eustermann, S, Yang, J, Videler, H.
登録日2010-08-30
公開日2011-02-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger.
J.Mol.Biol., 407, 2011
2KQC
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Second PBZ domain of human APLF protein
分子名称: Aprataxin and PNK-like factor, ZINC ION
著者Neuhaus, D, Eustermann, S, Brockmann, C, Yang, J.
登録日2009-11-04
公開日2010-01-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).
Nat.Struct.Mol.Biol., 17, 2010
2KQB
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First PBZ domain of human APLF protein
分子名称: Aprataxin and PNK-like factor, ZINC ION
著者Neuhaus, D, Eustermann, S, Brockmann, C, Yang, J.
登録日2009-11-04
公開日2010-01-19
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).
Nat.Struct.Mol.Biol., 17, 2010
2N8A
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1H, 13C and 15N chemical shift assignments and solution structure for PARP-1 F1F2 domains in complex with a DNA single-strand break
分子名称: DNA (45-MER), Poly [ADP-ribose] polymerase 1, ZINC ION
著者Neuhaus, D, Eustermann, S, Yang, J, Wu, W.
登録日2015-10-08
公開日2015-12-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1.
Mol.Cell, 60, 2015
1T2V
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Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide
分子名称: BRCTide-7PS, Breast cancer type 1 susceptibility protein
著者Williams, R.S, Lee, M.S, Hau, D.D, Glover, J.N.M.
登録日2004-04-22
公開日2004-05-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1
Nat.Struct.Mol.Biol., 11, 2004
1ZGU
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Solution structure of the human Mms2-Ubiquitin complex
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 variant 2
著者Lewis, M.J, Saltibus, L.F, Hau, D.D, Xiao, W, Spyracopoulos, L.
登録日2005-04-22
公開日2006-04-04
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Basis for Non-Covalent Interaction Between Ubiquitin and the Ubiquitin Conjugating Enzyme Variant Human MMS2.
J.Biomol.Nmr, 34, 2006
2LH8
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BU of 2lh8 by Molmil
Syrian hamster prion protein with thiamine
分子名称: 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, Major prion protein
著者Perez-Pineiro, R, Bjorndahl, T.C, Berjanskii, M, Hau, D, Li, L, Huang, A, Lee, R, Gibbs, E, Ladner, C, Wei Dong, Y, Abera, A, Cashman, N.R, Wishart, D.
登録日2011-08-05
公開日2011-09-14
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The prion protein binds thiamine.
Febs J., 278, 2011
2JMD
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Solution Structure of the Ring Domain of Human TRAF6
分子名称: TNF receptor-associated factor 6, ZINC ION
著者Mercier, P, Lewis, M.J, Hau, D.D, Saltibus, L.F, Xiao, W, Spyracopoulos, L.
登録日2006-11-02
公開日2007-04-10
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Structure, interactions, and dynamics of the RING domain from human TRAF6
Protein Sci., 16, 2007
3ZNR
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HDAC7 bound with inhibitor TMP269
分子名称: HISTONE DEACETYLASE 7, N-{[4-(4-phenyl-1,3-thiazol-2-yl)tetrahydro-2H-pyran-4-yl]methyl}-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, POTASSIUM ION, ...
著者Lobera, m, madauss, k, pohlhaus, d, trump, r, nolan, m.
登録日2013-02-15
公開日2013-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Selective Class Iia Histone Deacetylase Inhibition Via a Non-Chelating Zinc Binding Group
Nat.Chem.Biol., 9, 2013
3ZNS
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HDAC7 bound with TFMO inhibitor tmp942
分子名称: HISTONE DEACETYLASE 7, N-{[1-methyl-4-(4-phenyl-1,3-thiazol-2-yl)piperidin-4-yl]methyl}-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, POTASSIUM ION, ...
著者Lobera, M, Madauss, K.P, Pohlhaus, D.T, Trump, R.P, Nolan, M.A.
登録日2013-02-15
公開日2013-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Selective Class Iia Histone Deacetylase Inhibition Via a Non-Chelating Zinc Binding Group
Nat.Chem.Biol., 9, 2013
3EYM
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Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion
分子名称: 2-tert-butylbenzene-1,4-diol, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
著者Russell, R.J, Kerry, P.S, Stevens, D.A, Steinhauer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J.
登録日2008-10-21
公開日2009-01-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion
Proc.Natl.Acad.Sci.USA, 105, 2008
2VRD
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THE STRUCTURE OF THE ZINC FINGER FROM THE HUMAN SPLICEOSOMAL PROTEIN U1C
分子名称: U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C, ZINC ION
著者Muto, Y, Pomeranz-Krummel, D, Oubridge, C, Hernandez, H, Robinson, C, Neuhaus, D, Nagai, K.
登録日2008-03-31
公開日2008-04-08
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Structure and Biochemical Properties of the Human Spliceosomal Protein U1C
J.Mol.Biol., 341, 2004
5MIH
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Crystal structure of the lectin LecA from Pseudomonas aeruginosa in complex with a phenyl-epoxy-galactopyranoside
分子名称: 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CALCIUM ION, PA-I galactophilic lectin, ...
著者Wagner, S, Hauk, D, Hofmann, M, Joachim, I, Sommer, R, Muller, R, Imberty, A, Varrot, A, Titz, A.
登録日2016-11-28
公開日2017-10-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging.
Angew. Chem. Int. Ed. Engl., 56, 2017
7BBF
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Crystal structure of ubiquitin charged Ube2N (Ube2N~Ub) in complex with Ube2V2
分子名称: Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
著者Kiss, L, Neuhaus, D, James, L.C.
登録日2020-12-17
公開日2021-01-27
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination.
Nat Commun, 12, 2021
6GYI
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Azurin fom Pseudomonas aeruginosa treated with hydrosulfide
分子名称: Azurin, CALCIUM ION, COPPER (II) ION
著者Palm, G.J, Kohlhause, D.
登録日2018-06-29
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Azurin and HS-: towards implementation of a sensor for HS-detection.
Eur J Inorg Chem, 2019

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