3ZNR
HDAC7 bound with inhibitor TMP269
Summary for 3ZNR
Entry DOI | 10.2210/pdb3znr/pdb |
Related | 3ZNS |
Descriptor | HISTONE DEACETYLASE 7, ZINC ION, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | hydrolase, class iia hdacs, tfmo |
Biological source | HOMO SAPIENS |
Cellular location | Nucleus: Q8WUI4 |
Total number of polymer chains | 3 |
Total formula weight | 137696.58 |
Authors | Lobera, m.,madauss, k.,pohlhaus, d.,trump, r.,nolan, m. (deposition date: 2013-02-15, release date: 2013-03-27, Last modification date: 2024-05-08) |
Primary citation | Lobera, M.,Madauss, K.P.,Pohlhaus, D.T.,Wright, Q.G.,Trocha, M.,Schmidt, D.R.,Baloglu, E.,Trump, R.P.,Head, M.S.,Hofmann, G.A.,Murray-Thompson, M.,Schwartz, B.,Chakravorty, S.,Wu, Z.,Mander, P.K.,Kruidenier, L.,Reid, R.A.,Burkhart, W.,Turunen, B.J.,Rong, J.X.,Wagner, C.,Moyer, M.B.,Wells, C.,Hong, X.,Moore, J.T.,Williams, J.D.,Soler, D.,Ghosh, S.,Nolan, M.A. Selective Class Iia Histone Deacetylase Inhibition Via a Non-Chelating Zinc Binding Group Nat.Chem.Biol., 9:319-, 2013 Cited by PubMed: 23524983DOI: 10.1038/NCHEMBIO.1223 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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