5MIH

Crystal structure of the lectin LecA from Pseudomonas aeruginosa in complex with a phenyl-epoxy-galactopyranoside

Summary for 5MIH

Entry DOI	10.2210/pdb5mih/pdb
Descriptor	PA-I galactophilic lectin, CALCIUM ION, phenyl 6,7-anhydro-D-glycero-beta-D-galacto-heptopyranoside, ... (5 entities in total)
Functional Keywords	lectin, galactose binding protein, covalent lectin inhibition, sugar binding protein
Biological source	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Cellular location	Cytoplasm: Q05097
Total number of polymer chains	4
Total formula weight	52522.16
Authors	Wagner, S.,Hauk, D.,Hofmann, M.,Joachim, I.,Sommer, R.,Muller, R.,Imberty, A.,Varrot, A.,Titz, A. (deposition date: 2016-11-28, release date: 2017-10-11, Last modification date: 2024-01-17)
Primary citation	Wagner, S.,Hauck, D.,Hoffmann, M.,Sommer, R.,Joachim, I.,Muller, R.,Imberty, A.,Varrot, A.,Titz, A. Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging. Angew. Chem. Int. Ed. Engl., 56:16559-16564, 2017 Cited by PubMed: 28960731 DOI: 10.1002/anie.201709368 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation