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PDB: 162 件

4AQF
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X-ray crystallographic structure of Crimean-congo haemorrhagic fever virus nucleoprotein
分子名称: NUCLEOPROTEIN, SULFATE ION
著者Wang, Y, Dutta, S, Karlberg, H, Devignot, S, Weber, F, Hao, Q, Tan, Y.J, Mirazimi, A, Kotaka, M.
登録日2012-04-17
公開日2012-09-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of Crimean-Congo Haemorraghic Fever Virus Nucleoprotein: Superhelical Homo-Oligomers and the Role of Caspase-3 Cleavage.
J.Virol., 86, 2012
4AQG
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BU of 4aqg by Molmil
X-ray crystallographic structure of Crimean-congo haemorrhagic fever virus nucleoprotein
分子名称: NUCLEOPROTEIN, SULFATE ION
著者Wang, Y, Dutta, S, Karlberg, H, Devignot, S, Weber, F, Hao, Q, Tan, Y.J, Mirazimi, A, Kotaka, M.
登録日2012-04-17
公開日2012-09-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Crimean-Congo Haemorraghic Fever Virus Nucleoprotein: Superhelical Homo-Oligomers and the Role of Caspase-3 Cleavage.
J.Virol., 86, 2012
3U4H
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BU of 3u4h by Molmil
CD38 structure-based inhibitor design using the N1-cyclic inosine 5'-diphosphate ribose template
分子名称: 8-Amino-N1-Cyclic Inosine 5'-Diphosphoribose, ADP-ribosyl cyclase 1
著者Liu, Q, Hao, Q, Lee, H.C, Graeff, R.
登録日2011-10-08
公開日2012-10-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.878 Å)
主引用文献CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5'-Diphosphate Ribose Template
Plos One, 8, 2013
4OIC
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Crystal structrual of a soluble protein
分子名称: (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Bet v I allergen-like, CHLORIDE ION, ...
著者He, Y, Hao, Q, Li, W, Yan, C, Yan, N, Yin, P.
登録日2014-01-19
公開日2015-01-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Identification and characterization of ABA receptors in Oryza sativa
Plos One, 9, 2014
4NZW
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BU of 4nzw by Molmil
Crystal Structure of STK25-MO25 Complex
分子名称: 5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, Calcium-binding protein 39, Serine/threonine-protein kinase 25
著者Feng, M, Hao, Q, Zhou, Z.C.
登録日2013-12-13
公開日2014-12-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.583 Å)
主引用文献Structural insights into regulatory mechanisms of MO25-mediated kinase activation.
J.Struct.Biol., 186, 2014
4R8M
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BU of 4r8m by Molmil
Human SIRT2 crystal structure in complex with BHJH-TM1
分子名称: BHJH-TM1 peptide, NAD-dependent protein deacetylase sirtuin-2, ZINC ION, ...
著者Teng, Y.B, Hao, Q, Lin, H.N, Jing, H.
登録日2014-09-02
公開日2015-03-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Efficient Demyristoylase Activity of SIRT2 Revealed by Kinetic and Structural Studies
Sci Rep, 5, 2015
2OQU
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BU of 2oqu by Molmil
High Pressure Cryocooling of Capillary Sample Cryoprotection and Diffraction Phasing at Long Wavelengths
分子名称: CALCIUM ION, Elastase-1, SULFATE ION, ...
著者Kim, C.U, Hao, Q, Gruner, S.M.
登録日2007-02-01
公開日2007-05-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High-pressure cryocooling for capillary sample cryoprotection and diffraction phasing at long wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
2OQN
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High Pressure Cryocooling of Capillary Sample Cryoprotection and Diffraction Phasing at Long Wavelengths
分子名称: D(-)-TARTARIC ACID, Thaumatin-1
著者Kim, C.U, Hao, Q, Gruner, S.M.
登録日2007-01-31
公開日2007-05-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High-pressure cryocooling for capillary sample cryoprotection and diffraction phasing at long wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
5H6Y
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BU of 5h6y by Molmil
The BPTF Bromodomain Recognising H4K12Cr peptide
分子名称: GLY-KCR-GLY, Nucleosome-remodeling factor subunit BPTF
著者Wang, Y, Hao, Q.
登録日2016-11-15
公開日2017-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The BPTF Bromodomain Recognising H4K12Cr peptide
To Be Published
5J5L
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CRYSTAL STRUCTURE OF AFMP4P IN COMPLEX WITH ARACHIDONIC ACID
分子名称: ARACHIDONIC ACID, Uncharacterized protein
著者Zhang, H, Hao, Q.
登録日2016-04-03
公開日2017-04-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A Novel Class Of Virulence Factors In Penicillium Marneffei And Aspergillus Fumigatus Enhances Intracellular Survival In Monocytes By Arachidonic Acid Binding
To Be Published
5WTD
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BU of 5wtd by Molmil
Structure of human serum transferrin bound ruthenium at N-lobe
分子名称: FE (III) ION, MALONATE ION, RUTHENIUM ION, ...
著者Sun, H, Wang, M, Lai, T.P, Zhang, H, Hao, Q.
登録日2016-12-11
公開日2017-12-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake.
J.Inorg.Biochem., 234, 2022
5WYI
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BU of 5wyi by Molmil
The Yaf9 YEATS domain Recognizing H3K122suc Peptide
分子名称: (2S)-2-azanyl-6-[(4-hydroxy-4-oxo-butanoyl)amino]hexanoic acid, ILE-MET-PRO-LYS-ASP-ILE-GLN-LEU, SUCCINIC ACID, ...
著者Wang, Y, Hao, Q.
登録日2017-01-13
公開日2018-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Yaf9 YEATS domain Recognizing H3K122suc Peptide
To Be Published
5BNI
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Porcine CD38 complexed with complexed with a covalent intermediate, ribo-F-ribose-5'-phosphate
分子名称: Uncharacterized protein, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4S)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate
著者Ting, K.Y, Leung, C.F.P, Graeff, R.M, Lee, H.C, Hao, Q, Kotaka, M.
登録日2015-05-26
公開日2016-05-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Porcine CD38 exhibits prominent secondary NAD(+) cyclase activity.
Protein Sci., 25, 2016
8SL1
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BU of 8sl1 by Molmil
Cryo-EM structure of PAPP-A2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Judge, R.A, Stoll, V.S, Eaton, D, Hao, Q, Bratkowski, M.A.
登録日2023-04-20
公開日2023-11-08
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Cryo-EM structure of human PAPP-A2 and mechanism of substrate recognition.
Commun Chem, 6, 2023
5CSD
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BU of 5csd by Molmil
Ligand binding domain 2 of Penicillium marneffei MP1 protein in complex with arachidonic acids
分子名称: ARACHIDONIC ACID, Envelope glycoprotein, GLYCEROL
著者Lam, W.H, Zhang, H, Hao, Q.
登録日2015-07-23
公開日2016-07-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Talaromyces marneffei Mp1p Is a Virulence Factor that Binds and Sequesters a Key Proinflammatory Lipid to Dampen Host Innate Immune Response
Cell Chem Biol, 24, 2017
5E7X
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BU of 5e7x by Molmil
Ligand binding domain 1 of Penicillium marneffei MP1 protein in complex with palmitic acid
分子名称: ACETATE ION, Cell wall antigen, GLYCEROL, ...
著者Lam, W.H, Zhang, H, Hao, Q.
登録日2015-10-13
公開日2016-10-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Talaromyces marneffeiMp1 protein, a novel virulence factor, carries two arachidonic acid-binding domains to suppress inflammatory responses in hosts.
Infect. Immun., 2019
5ECF
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BU of 5ecf by Molmil
Ligand binding domain 1 of Penicillium marneffei MP1 protein complexed with arachidonic acids
分子名称: ARACHIDONIC ACID, Cell wall antigen
著者Lam, W.H, Zhang, H, Hao, Q.
登録日2015-10-20
公開日2016-10-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Talaromyces marneffeiMp1 protein, a novel virulence factor, carries two arachidonic acid-binding domains to suppress inflammatory responses in hosts
Infect. Immun., 2019
5F1K
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BU of 5f1k by Molmil
human CD38 in complex with nanobody MU1053
分子名称: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, nanobody MU1053
著者Zhang, H, Hao, Q.
登録日2015-11-30
公開日2016-06-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Immuno-targeting the multifunctional CD38 using nanobody
Sci Rep, 6, 2016
5F1O
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BU of 5f1o by Molmil
human CD38 in complex with nanobody MU551
分子名称: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, nanobody MU551
著者Zhang, H, Hao, Q.
登録日2015-11-30
公開日2016-06-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Immuno-targeting the multifunctional CD38 using nanobody
Sci Rep, 6, 2016
3QYT
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BU of 3qyt by Molmil
Diferric bound human serum transferrin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
著者Yang, N, Zhang, H, Wang, M, Hao, Q, Sun, H.
登録日2011-03-03
公開日2012-03-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe
Sci Rep, 2, 2012
3ROQ
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BU of 3roq by Molmil
Crystal structure of human CD38 in complex with compound CZ-46
分子名称: (2R,3R,4S,5S)-4-fluoro-3,5-dihydroxytetrahydrofuran-2-yl 2-phenylethyl hydrogen (S)-phosphate, ADP-ribosyl cyclase 1
著者Zhang, H, Lee, H.C, Hao, Q.
登録日2011-04-26
公開日2011-12-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Catalysis-based inhibitors of the calcium signaling function of CD38.
Biochemistry, 51, 2012
3ROM
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BU of 3rom by Molmil
Crystal structure of human CD38 in complex with compound CZ-48
分子名称: 2-deoxy-2-fluoro-5-O-thiophosphono-alpha-D-arabinofuranose, ADP-ribosyl cyclase 1
著者Zhang, H, Lee, H.C, Hao, Q.
登録日2011-04-26
公開日2011-12-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Catalysis-based inhibitors of the calcium signaling function of CD38.
Biochemistry, 51, 2012
3RAJ
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BU of 3raj by Molmil
Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7
分子名称: ADP-ribosyl cyclase 1, heavy chain of the Fab fragment of antibody HB7, light chain of the Fab fragment of antibody HB7
著者Zhang, H, Lee, H.C, Hao, Q.
登録日2011-03-28
公開日2011-04-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.044 Å)
主引用文献Engineering a novel cytosolic form of CD38 for cyclic ADP-ribose dependent signaling
To be Published
3RIY
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BU of 3riy by Molmil
Sirt5 is an NAD-dependent protein lysine demalonylase and desuccinylase
分子名称: NAD-dependent deacetylase sirtuin-5, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION, ...
著者Zhou, Y, Hao, Q.
登録日2011-04-14
公開日2011-11-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
Science, 334, 2011
3ROK
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BU of 3rok by Molmil
Crystal structure of human CD38 in complex with compound CZ-27
分子名称: 5-O-[(S)-butoxy(hydroxy)phosphoryl]-2-deoxy-2-fluoro-alpha-D-arabinofuranose, ADP-ribosyl cyclase 1
著者Zhang, H, Lee, H.C, Hao, Q.
登録日2011-04-26
公開日2011-12-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Catalysis-based inhibitors of the calcium signaling function of CD38.
Biochemistry, 51, 2012

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