5VF3
 
 | | Bacteriophage T4 isometric capsid | | Descriptor: | Capsid vertex protein gp24, Highly immunogenic outer capsid protein, Major capsid protein, ... | | Authors: | Chen, Z, Sun, L, Zhang, Z, Fokine, A, Padilla-Sanchez, V, Hanein, D, Jiang, W, Rossmann, M.G, Rao, V.B. | | Deposit date: | 2017-04-06 | | Release date: | 2017-09-13 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structure of the bacteriophage T4 isometric head at 3.3- angstrom resolution and its relevance to the assembly of icosahedral viruses.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8HPA
 | | Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in a DNA binding form | | Descriptor: | DNA (5'-D(*CP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*TP*AP*C)-3'), DNA (5'-D(P*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*CP*G)-3'), DNA polymerase, ... | | Authors: | Xu, Y, Wu, Y, Zhang, Y, Fan, R, Yang, Y, Li, D, Yang, B, Zhang, Z, Dong, C. | | Deposit date: | 2022-12-12 | | Release date: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Structure of DNA replication machinery from human monkeypox virus
To Be Published
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4E57
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8A5Y
 | | S. cerevisiae apo unphosphorylated APC/C. | | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ... | | Authors: | Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J. | | Deposit date: | 2022-06-16 | | Release date: | 2022-08-31 | | Last modified: | 2023-07-26 | | Method: | ELECTRON MICROSCOPY (4.9 Å) | | Cite: | Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex and comparison to apo unphosphorylated and phosphorylated states
To Be Published
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6BF8
 | | Cryo-EM structure of human insulin degrading enzyme in complex with insulin | | Descriptor: | Insulin-degrading enzyme | | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | | Deposit date: | 2017-10-26 | | Release date: | 2018-04-04 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
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6BFC
 | | Cryo-EM structure of human insulin degrading enzyme in complex with insulin | | Descriptor: | Insulin, Insulin-degrading enzyme | | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | | Deposit date: | 2017-10-26 | | Release date: | 2017-12-27 | | Last modified: | 2021-04-28 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
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6B7Y
 | | Cryo-EM structure of human insulin degrading enzyme | | Descriptor: | Insulin-degrading enzyme | | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | | Deposit date: | 2017-10-05 | | Release date: | 2017-11-08 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (6.5 Å) | | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
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6B3Q
 | | Cryo-EM structure of human insulin degrading enzyme in complex with insulin | | Descriptor: | Insulin, Insulin-degrading enzyme | | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | | Deposit date: | 2017-09-22 | | Release date: | 2017-11-22 | | Last modified: | 2021-04-28 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
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6BF6
 | | Cryo-EM structure of human insulin degrading enzyme | | Descriptor: | Insulin-degrading enzyme | | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | | Deposit date: | 2017-10-26 | | Release date: | 2018-02-07 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (6.5 Å) | | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
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6B7Z
 | | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11 heavy chain and FAB H11 light chain | | Descriptor: | FAB H11 heavy chain, FAB H11 light chain, Insulin-degrading enzyme | | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | | Deposit date: | 2017-10-05 | | Release date: | 2018-01-10 | | Last modified: | 2021-04-28 | | Method: | ELECTRON MICROSCOPY (6.5 Å) | | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
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6BF9
 | | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain | | Descriptor: | Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme | | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | | Deposit date: | 2017-10-26 | | Release date: | 2018-02-07 | | Last modified: | 2021-04-28 | | Method: | ELECTRON MICROSCOPY (7.2 Å) | | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
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6BF7
 | | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain | | Descriptor: | Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme | | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | | Deposit date: | 2017-10-26 | | Release date: | 2018-02-07 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (6.5 Å) | | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
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7U5J
 | | Cryo-EM Structure of ALDOA | | Descriptor: | Fructose-bisphosphate aldolase | | Authors: | Morgan, C.E, Zhang, Z, Yu, E.W. | | Deposit date: | 2022-03-02 | | Release date: | 2022-12-14 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.96 Å) | | Cite: | Toward structural-omics of the bovine retinal pigment epithelium.
Cell Rep, 41, 2022
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7U5M
 | | Cryo-EM Structure of GAPDH | | Descriptor: | Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Morgan, C.E, Zhang, Z, Yu, E.W. | | Deposit date: | 2022-03-02 | | Release date: | 2022-12-14 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.28 Å) | | Cite: | Toward structural-omics of the bovine retinal pigment epithelium.
Cell Rep, 41, 2022
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7U5N
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7U5I
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8XV2
 | | Thiamine-bound human SLC19A3 | | Descriptor: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, Soluble cytochrome b562,Thiamine transporter 2 | | Authors: | Dang, Y, Wang, G.P, Zhang, Z. | | Deposit date: | 2024-01-14 | | Release date: | 2024-03-27 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Substrate and drug recognition mechanisms of SLC19A3.
Cell Res., 34, 2024
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8XV5
 | | Pyridoxamine-bound human SLC19A3 | | Descriptor: | 4-(AMINOMETHYL)-5-(HYDROXYMETHYL)-2-METHYLPYRIDIN-3-OL, Soluble cytochrome b562,Thiamine transporter 2 | | Authors: | Dang, Y, Wang, G.P, Zhang, Z. | | Deposit date: | 2024-01-14 | | Release date: | 2024-03-27 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Substrate and drug recognition mechanisms of SLC19A3.
Cell Res., 34, 2024
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8XV9
 | | Fedratinib-bound human SLC19A3 | | Descriptor: | N-tert-butyl-3-{[5-methyl-2-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]amino}benzenesulfonamide, Soluble cytochrome b562,Thiamine transporter 2 | | Authors: | Dang, Y, Wang, G.P, Zhang, Z. | | Deposit date: | 2024-01-14 | | Release date: | 2024-03-27 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Substrate and drug recognition mechanisms of SLC19A3.
Cell Res., 34, 2024
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5KQG
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8A61
 | | S. cerevisiae apo phosphorylated APC/C | | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ... | | Authors: | Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J. | | Deposit date: | 2022-06-16 | | Release date: | 2022-08-31 | | Method: | ELECTRON MICROSCOPY (5.4 Å) | | Cite: | Cryo-EM structure of the S. cerevisiae apo phosphorylated APC/C
To Be Published
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8A3T
 | | S. cerevisiae APC/C-Cdh1 complex | | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ... | | Authors: | Barford, D, Vazquez-Fernandez, E, Zhang, Z, Yang, J. | | Deposit date: | 2022-06-09 | | Release date: | 2022-08-31 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex
To Be Published
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6B70
 | | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain and insulin | | Descriptor: | FAB H11-E heavy chain, FAB H11-E light chain, Insulin, ... | | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | | Deposit date: | 2017-10-03 | | Release date: | 2017-12-27 | | Last modified: | 2021-04-28 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
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5KQL
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5KQP
 | | Crystal structure of Apo-form LMW-PTP | | Descriptor: | Low molecular weight phosphotyrosine protein phosphatase | | Authors: | Wang, J, Zhang, Z.-Y, Yu, Z.-H. | | Deposit date: | 2016-07-06 | | Release date: | 2016-10-12 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.052 Å) | | Cite: | Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism.
J.Med.Chem., 2016
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