5JYP
| Allosteric inhibition of Kidney Isoform of Glutaminase | Descriptor: | 2-phenyl-~{N}-[5-[(1~{S},3~{S})-3-[5-(2-phenylethanoylamino)-1,3,4-thiadiazol-2-yl]cyclohexyl]-1,3,4-thiadiazol-2-yl]ethanamide, Glutaminase kidney isoform, mitochondrial | Authors: | Ramachandran, S, Sivaraman, J. | Deposit date: | 2016-05-15 | Release date: | 2016-08-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Structural basis for exploring the allosteric inhibition of human kidney type glutaminase. Oncotarget, 7, 2016
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7ZL3
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8BYR
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5YY5
| Structural definition of a unique neutralization epitope on the receptor-binding domain of MERS-CoV spike glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain, Light chain, ... | Authors: | Zhang, S, Wang, P, Zhou, P, Wang, X, Zhang, L. | Deposit date: | 2017-12-08 | Release date: | 2018-08-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein Cell Rep, 24, 2018
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6H42
| crystal structure of the human TGT catalytic subunit QTRT1 | Descriptor: | BROMIDE ION, CHLORIDE ION, GLUTAMIC ACID, ... | Authors: | Johannsson, S, Neumann, P, Ficner, R. | Deposit date: | 2018-07-20 | Release date: | 2018-09-05 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal Structure of the Human tRNA Guanine Transglycosylase Catalytic Subunit QTRT1. Biomolecules, 8, 2018
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6FXB
| Bovine beta-lactoglobulin variant A at pH 4.0 | Descriptor: | DI(HYDROXYETHYL)ETHER, Major allergen beta-lactoglobulin, NITRATE ION | Authors: | Khan, S, Ipsen, R, Almdal, K, Svensson, B, Harris, P. | Deposit date: | 2018-03-08 | Release date: | 2018-05-23 | Last modified: | 2019-02-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Revealing the Dimeric Crystal and Solution Structure of beta-Lactoglobulin at pH 4 and Its pH and Salt Dependent Monomer-Dimer Equilibrium. Biomacromolecules, 19, 2018
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6OAP
| Crystal structure of a dual sensor histidine kinase in the green-light absorbing Pg state | Descriptor: | Dual sensor histidine kinase, MAGNESIUM ION, PHYCOCYANOBILIN | Authors: | Heewhan, S, Zhong, R, Xiaoli, Z, Sepalika, B, Xiaojing, Y. | Deposit date: | 2019-03-18 | Release date: | 2019-09-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural basis of molecular logic OR in a dual-sensor histidine kinase. Proc.Natl.Acad.Sci.USA, 116, 2019
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5ZXV
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5E59
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8QSM
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8QSL
| Cryo-EM structure of human SLC15A4 dimer in outward open state in LMNG | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Rehan, S, Matsuoka, R, Jazayeri, A, Duerr, K.L. | Deposit date: | 2023-10-10 | Release date: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (2.81 Å) | Cite: | Cryo-EM structure of human SLC15A4 dimer in outward open state in LMNG To Be Published
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8QSN
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8QSK
| Cryo-EM structure of human SLC15A4 dimer in outward open state in MSP1D1 nanodisc | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Rehan, S, Matsuoka, R, Jazayeri, A, Duerr, K.L. | Deposit date: | 2023-10-10 | Release date: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structure of human SLC15A4 dimer in outward open state in MSP1D1 nanodisc To Be Published
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5BN4
| Structure of a unique ATP synthase NeqA-NeqB in complex with ANP from Nanoarcheaum equitans | Descriptor: | MAGNESIUM ION, NEQ263, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J. | Deposit date: | 2015-05-25 | Release date: | 2015-09-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.699 Å) | Cite: | Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans J.Biol.Chem., 290, 2015
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5BO5
| Structure of a unique ATP synthase subunit NeqB from Nanoarcheaum equitans | Descriptor: | MAGNESIUM ION, NEQ263, SULFATE ION | Authors: | Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J. | Deposit date: | 2015-05-27 | Release date: | 2015-09-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.808 Å) | Cite: | Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans J.Biol.Chem., 290, 2015
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8GWR
| Near full length Kidney type Glutaminase in complex with 2,2-Dimethyl-2,3-Dihydrobenzo[a] Phenanthridin-4(1H)-one (DDP) | Descriptor: | 2,2-dimethyl-1,3-dihydrobenzo[a]phenanthridin-4-one, Glutaminase kidney isoform, mitochondrial | Authors: | Shankar, S, Jobichen, C, Sivaraman, J. | Deposit date: | 2022-09-17 | Release date: | 2022-12-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | A novel allosteric site employs a conserved inhibition mechanism in human kidney-type glutaminase. Febs J., 290, 2023
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8K70
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5AEI
| Designed Armadillo repeat protein YIIIM5AII in complex with peptide (KR)5 | Descriptor: | ACETATE ION, CALCIUM ION, DESIGNED ARMADILLO REPEAT PROTEIN YIIIM5AII, ... | Authors: | Hansen, S, Tremmel, D, Madhurantakam, C, Reichen, C, Mittl, P, Plueckthun, A. | Deposit date: | 2015-08-31 | Release date: | 2016-03-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structure and Energetic Contributions of a Designed Modular Peptide-Binding Protein with Picomolar Affinity. J.Am.Chem.Soc., 138, 2016
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8HY5
| Structure of D-amino acid oxidase mutant R38H | Descriptor: | 1,2-ETHANEDIOL, BENZOIC ACID, D-amino-acid oxidase, ... | Authors: | Khan, S, Upadhyay, S, Dave, U, Kumar, A, Gomes, J. | Deposit date: | 2023-01-05 | Release date: | 2023-01-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and mechanistic insights into ALS patient derived mutations in D-amino acid oxidase. Int.J.Biol.Macromol., 256, 2023
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5DTD
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7UM7
| CryoEM structure of Go-coupled 5-HT5AR in complex with Methylergometrine | Descriptor: | (8beta)-N-[(2S)-1-hydroxybutan-2-yl]-6-methyl-9,10-didehydroergoline-8-carboxamide, 5-hydroxytryptamine receptor 5A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhang, S, Fay, J.F, Roth, B.L. | Deposit date: | 2022-04-06 | Release date: | 2022-07-20 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | Inactive and active state structures template selective tools for the human 5-HT 5A receptor. Nat.Struct.Mol.Biol., 29, 2022
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7UM5
| CryoEM structure of Go-coupled 5-HT5AR in complex with 5-CT | Descriptor: | 3-(2-azanylethyl)-1H-indole-5-carboxamide, 5-hydroxytryptamine receptor 5A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhang, S, Fay, J.F, Roth, B.L. | Deposit date: | 2022-04-06 | Release date: | 2022-07-20 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | Inactive and active state structures template selective tools for the human 5-HT 5A receptor. Nat.Struct.Mol.Biol., 29, 2022
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7UM6
| CryoEM structure of Go-coupled 5-HT5AR in complex with Lisuride | Descriptor: | 5-hydroxytryptamine receptor 5A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhang, S, Fay, J.F, Roth, B.L. | Deposit date: | 2022-04-06 | Release date: | 2022-07-20 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Inactive and active state structures template selective tools for the human 5-HT 5A receptor. Nat.Struct.Mol.Biol., 29, 2022
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5E3L
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5BN5
| Structural basis for a unique ATP synthase core complex from Nanoarcheaum equitans | Descriptor: | NEQ263, SULFATE ION, V-type ATP synthase alpha chain | Authors: | Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J. | Deposit date: | 2015-05-25 | Release date: | 2015-09-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.997 Å) | Cite: | Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans J.Biol.Chem., 290, 2015
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