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PDB: 2049 results

5JYP
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BU of 5jyp by Molmil
Allosteric inhibition of Kidney Isoform of Glutaminase
Descriptor: 2-phenyl-~{N}-[5-[(1~{S},3~{S})-3-[5-(2-phenylethanoylamino)-1,3,4-thiadiazol-2-yl]cyclohexyl]-1,3,4-thiadiazol-2-yl]ethanamide, Glutaminase kidney isoform, mitochondrial
Authors:Ramachandran, S, Sivaraman, J.
Deposit date:2016-05-15
Release date:2016-08-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Structural basis for exploring the allosteric inhibition of human kidney type glutaminase.
Oncotarget, 7, 2016
7ZL3
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BU of 7zl3 by Molmil
Signal peptide mimicry primes Sec61 for client-selective inhibition
Descriptor: Cyclic depsipeptide signal peptide mimic, Protein transport protein Sec61 subunit alpha, Protein transport protein Sec61 subunit beta, ...
Authors:Rehan, S, Paavilainen O, V.
Deposit date:2022-04-13
Release date:2023-03-22
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Signal peptide mimicry primes Sec61 for client-selective inhibition.
Nat.Chem.Biol., 19, 2023
8BYR
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BU of 8byr by Molmil
Crystal structure of MoaB2 protein from Mycobacterium smegmatis
Descriptor: Molybdopterin biosynthesis protein
Authors:Narasimhan, S, Sanderova, H, Zidek, L, Krasny, L.
Deposit date:2022-12-21
Release date:2024-07-10
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:MoaB2 binds to sA in Mycobacterium smegmatis and modulates its activity and biological stability
To Be Published
5YY5
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BU of 5yy5 by Molmil
Structural definition of a unique neutralization epitope on the receptor-binding domain of MERS-CoV spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain, Light chain, ...
Authors:Zhang, S, Wang, P, Zhou, P, Wang, X, Zhang, L.
Deposit date:2017-12-08
Release date:2018-08-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein
Cell Rep, 24, 2018
6H42
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BU of 6h42 by Molmil
crystal structure of the human TGT catalytic subunit QTRT1
Descriptor: BROMIDE ION, CHLORIDE ION, GLUTAMIC ACID, ...
Authors:Johannsson, S, Neumann, P, Ficner, R.
Deposit date:2018-07-20
Release date:2018-09-05
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal Structure of the Human tRNA Guanine Transglycosylase Catalytic Subunit QTRT1.
Biomolecules, 8, 2018
6FXB
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BU of 6fxb by Molmil
Bovine beta-lactoglobulin variant A at pH 4.0
Descriptor: DI(HYDROXYETHYL)ETHER, Major allergen beta-lactoglobulin, NITRATE ION
Authors:Khan, S, Ipsen, R, Almdal, K, Svensson, B, Harris, P.
Deposit date:2018-03-08
Release date:2018-05-23
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Revealing the Dimeric Crystal and Solution Structure of beta-Lactoglobulin at pH 4 and Its pH and Salt Dependent Monomer-Dimer Equilibrium.
Biomacromolecules, 19, 2018
6OAP
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BU of 6oap by Molmil
Crystal structure of a dual sensor histidine kinase in the green-light absorbing Pg state
Descriptor: Dual sensor histidine kinase, MAGNESIUM ION, PHYCOCYANOBILIN
Authors:Heewhan, S, Zhong, R, Xiaoli, Z, Sepalika, B, Xiaojing, Y.
Deposit date:2019-03-18
Release date:2019-09-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural basis of molecular logic OR in a dual-sensor histidine kinase.
Proc.Natl.Acad.Sci.USA, 116, 2019
5ZXV
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BU of 5zxv by Molmil
Structural definition of a unique neutralization epitope on the receptor-binding domain of MERS-CoV spike glycoprotein
Descriptor: MERS-CoV RBD, heavy chain, light chain
Authors:Zhang, S, Wang, X.
Deposit date:2018-05-21
Release date:2018-07-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (4.482 Å)
Cite:Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein
Cell Rep, 24, 2018
5E59
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BU of 5e59 by Molmil
Crystal structure of reduced state of a novel disulfide oxidoreductase from Deinococcus radiodurans
Descriptor: FrnE protein, GLYCEROL
Authors:Bihani, S.C, Panicker, L, Kumar, V.
Deposit date:2015-10-08
Release date:2016-10-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:drFrnE Represents a Hitherto Unknown Class of Eubacterial Cytoplasmic Disulfide Oxido-Reductases.
Antioxid. Redox Signal., 28, 2018
8QSM
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BU of 8qsm by Molmil
Cryo-EM structure of human SLC15A4 monomer in outward open state in LMNG
Descriptor: Solute carrier family 15 member 4
Authors:Rehan, S, Matsuoka, R, Jazayeri, A, Duerr, K.L.
Deposit date:2023-10-10
Release date:2023-10-25
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:Cryo-EM structure of human SLC15A4 monomer in outward open state in LMNG
To Be Published
8QSL
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Cryo-EM structure of human SLC15A4 dimer in outward open state in LMNG
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
Authors:Rehan, S, Matsuoka, R, Jazayeri, A, Duerr, K.L.
Deposit date:2023-10-10
Release date:2023-10-25
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Cryo-EM structure of human SLC15A4 dimer in outward open state in LMNG
To Be Published
8QSN
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Cryo-EM structure of human SLC15A4 monomer in outward open state in PMAL C8
Descriptor: Solute carrier family 15 member 4
Authors:Rehan, S, Matsuoka, R, Jazayeri, A, Duerr, K.L.
Deposit date:2023-10-10
Release date:2023-10-25
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Cryo-EM structure of human SLC15A4 monomer in outward open state in PMAL C8
To Be Published
8QSK
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BU of 8qsk by Molmil
Cryo-EM structure of human SLC15A4 dimer in outward open state in MSP1D1 nanodisc
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
Authors:Rehan, S, Matsuoka, R, Jazayeri, A, Duerr, K.L.
Deposit date:2023-10-10
Release date:2023-11-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of human SLC15A4 dimer in outward open state in MSP1D1 nanodisc
To Be Published
5BN4
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BU of 5bn4 by Molmil
Structure of a unique ATP synthase NeqA-NeqB in complex with ANP from Nanoarcheaum equitans
Descriptor: MAGNESIUM ION, NEQ263, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J.
Deposit date:2015-05-25
Release date:2015-09-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.699 Å)
Cite:Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans
J.Biol.Chem., 290, 2015
5BO5
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BU of 5bo5 by Molmil
Structure of a unique ATP synthase subunit NeqB from Nanoarcheaum equitans
Descriptor: MAGNESIUM ION, NEQ263, SULFATE ION
Authors:Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J.
Deposit date:2015-05-27
Release date:2015-09-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.808 Å)
Cite:Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans
J.Biol.Chem., 290, 2015
8GWR
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BU of 8gwr by Molmil
Near full length Kidney type Glutaminase in complex with 2,2-Dimethyl-2,3-Dihydrobenzo[a] Phenanthridin-4(1H)-one (DDP)
Descriptor: 2,2-dimethyl-1,3-dihydrobenzo[a]phenanthridin-4-one, Glutaminase kidney isoform, mitochondrial
Authors:Shankar, S, Jobichen, C, Sivaraman, J.
Deposit date:2022-09-17
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:A novel allosteric site employs a conserved inhibition mechanism in human kidney-type glutaminase.
Febs J., 290, 2023
8K70
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BU of 8k70 by Molmil
Structural basis for the distinct roles of non-conserved Pro116 and conserved Tyr124 of BCH domain of yeast p50RhoGAP
Descriptor: Putative Rho GTPase-activating protein C1565.02c, TETRAETHYLENE GLYCOL
Authors:Shankar, S, Sivaraman, J.
Deposit date:2023-07-26
Release date:2024-05-29
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural basis for the distinct roles of non-conserved Pro116 and conserved Tyr124 of BCH domain of yeast p50RhoGAP.
Cell.Mol.Life Sci., 81, 2024
5AEI
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BU of 5aei by Molmil
Designed Armadillo repeat protein YIIIM5AII in complex with peptide (KR)5
Descriptor: ACETATE ION, CALCIUM ION, DESIGNED ARMADILLO REPEAT PROTEIN YIIIM5AII, ...
Authors:Hansen, S, Tremmel, D, Madhurantakam, C, Reichen, C, Mittl, P, Plueckthun, A.
Deposit date:2015-08-31
Release date:2016-03-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structure and Energetic Contributions of a Designed Modular Peptide-Binding Protein with Picomolar Affinity.
J.Am.Chem.Soc., 138, 2016
8HY5
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BU of 8hy5 by Molmil
Structure of D-amino acid oxidase mutant R38H
Descriptor: 1,2-ETHANEDIOL, BENZOIC ACID, D-amino-acid oxidase, ...
Authors:Khan, S, Upadhyay, S, Dave, U, Kumar, A, Gomes, J.
Deposit date:2023-01-05
Release date:2023-01-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and mechanistic insights into ALS patient derived mutations in D-amino acid oxidase.
Int.J.Biol.Macromol., 256, 2023
5DTD
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BU of 5dtd by Molmil
Crystal structure of Fis bound to 27bp DNA F1-8C (AAATTCGTTTGAATTTTGAGCGAATTT)
Descriptor: DNA (27-MER), DNA-binding protein Fis
Authors:Hancock, S.P, Cascio, D, Johnson, R.C.
Deposit date:2015-09-17
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.642 Å)
Cite:DNA Sequence Determinants Controlling Affinity, Stability and Shape of DNA Complexes Bound by the Nucleoid Protein Fis.
Plos One, 11, 2016
7UM7
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BU of 7um7 by Molmil
CryoEM structure of Go-coupled 5-HT5AR in complex with Methylergometrine
Descriptor: (8beta)-N-[(2S)-1-hydroxybutan-2-yl]-6-methyl-9,10-didehydroergoline-8-carboxamide, 5-hydroxytryptamine receptor 5A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Zhang, S, Fay, J.F, Roth, B.L.
Deposit date:2022-04-06
Release date:2022-07-20
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Inactive and active state structures template selective tools for the human 5-HT 5A receptor.
Nat.Struct.Mol.Biol., 29, 2022
7UM5
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BU of 7um5 by Molmil
CryoEM structure of Go-coupled 5-HT5AR in complex with 5-CT
Descriptor: 3-(2-azanylethyl)-1H-indole-5-carboxamide, 5-hydroxytryptamine receptor 5A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Zhang, S, Fay, J.F, Roth, B.L.
Deposit date:2022-04-06
Release date:2022-07-20
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Inactive and active state structures template selective tools for the human 5-HT 5A receptor.
Nat.Struct.Mol.Biol., 29, 2022
7UM6
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BU of 7um6 by Molmil
CryoEM structure of Go-coupled 5-HT5AR in complex with Lisuride
Descriptor: 5-hydroxytryptamine receptor 5A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhang, S, Fay, J.F, Roth, B.L.
Deposit date:2022-04-06
Release date:2022-07-20
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Inactive and active state structures template selective tools for the human 5-HT 5A receptor.
Nat.Struct.Mol.Biol., 29, 2022
5E3L
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BU of 5e3l by Molmil
Crystal structure of Fis bound to 27bp DNA F1-8G (AAATTGGTTTGAATTTTGAGCCAATTT)
Descriptor: DNA (27-MER), DNA-binding protein Fis
Authors:Hancock, S.P, Cascio, D, Johnson, R.C.
Deposit date:2015-10-03
Release date:2016-03-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:DNA Sequence Determinants Controlling Affinity, Stability and Shape of DNA Complexes Bound by the Nucleoid Protein Fis.
Plos One, 11, 2016
5BN5
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BU of 5bn5 by Molmil
Structural basis for a unique ATP synthase core complex from Nanoarcheaum equitans
Descriptor: NEQ263, SULFATE ION, V-type ATP synthase alpha chain
Authors:Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J.
Deposit date:2015-05-25
Release date:2015-09-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.997 Å)
Cite:Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans
J.Biol.Chem., 290, 2015

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PDB entries from 2024-10-09

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