6JCJ
| Structure of crolibulin in complex with tubulin | 分子名称: | (4R)-2,7,8-triamino-4-(3-bromo-4,5-dimethoxyphenyl)-4H-1-benzopyran-3-carbonitrile, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Zhang, Z, Yang, J. | 登録日 | 2019-01-29 | 公開日 | 2019-03-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular mechanism of crolibulin in complex with tubulin provides a rationale for drug design. Biochem. Biophys. Res. Commun., 511, 2019
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4OV4
| Isopropylmalate synthase binding with ketoisovalerate | 分子名称: | 2-isopropylmalate synthase, 3-METHYL-2-OXOBUTANOIC ACID, ZINC ION | 著者 | Zhang, Z, Wu, J, Wang, C, Zhang, P. | 登録日 | 2014-02-20 | 公開日 | 2014-08-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Subdomain II of alpha-isopropylmalate synthase is essential for activity: inferring a mechanism of feedback inhibition. J.Biol.Chem., 289, 2014
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3RL7
| Crystal structure of hDLG1-PDZ1 complexed with APC | 分子名称: | 11-mer peptide from Adenomatous polyposis coli protein, Disks large homolog 1 | 著者 | Zhang, Z, Li, H, Wu, G. | 登録日 | 2011-04-19 | 公開日 | 2011-12-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular basis for the recognition of adenomatous polyposis coli by the Discs Large 1 protein. Plos One, 6, 2011
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4OV9
| Structure of isopropylmalate synthase binding with alpha-isopropylmalate | 分子名称: | (2S)-2-hydroxy-2-(propan-2-yl)butanedioic acid, ZINC ION, isopropylmalate synthase | 著者 | Zhang, Z, Wu, J, Wang, C, Zhang, P. | 登録日 | 2014-02-20 | 公開日 | 2014-08-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Subdomain II of alpha-isopropylmalate synthase is essential for activity: inferring a mechanism of feedback inhibition. J.Biol.Chem., 289, 2014
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6L4K
| Human serum albumin-Palmitic acid-Cu compound | 分子名称: | 2-bromanyl-9-ethyl-~{N},~{N},7-trimethyl-3-thia-1$l^{4},5,6$l^{4},10-tetraza-2$l^{4}-cupratricyclo[6.4.0.0^{2,6}]dodeca-1(8),4,6,9,11-pentaen-4-amine, PALMITIC ACID, Serum albumin | 著者 | Zhang, Z.L. | 登録日 | 2019-10-17 | 公開日 | 2020-10-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | A novel brain-tumor-inhibiting copper(II) compound based on a human serum albumin-cell penetrating peptide conjugate To Be Published
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3T7U
| A NeW Crystal structure of APC-ARM | 分子名称: | Adenomatous polyposis coli protein, PHOSPHATE ION | 著者 | Zhang, Z, Wu, G. | 登録日 | 2011-07-31 | 公開日 | 2011-12-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of the armadillo repeat domain of adenomatous polyposis coli which reveals its inherent flexibility Biochem.Biophys.Res.Commun., 412, 2011
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6IVY
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6J9R
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4MBY
| Structure of B-Lymphotropic Polyomavirus VP1 in complex with 3'-sialyllactose | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Khan, Z.M, Neu, U, Stehle, T. | 登録日 | 2013-08-21 | 公開日 | 2013-12-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Structures of B-Lymphotropic Polyomavirus VP1 in Complex with Oligosaccharide Ligands. Plos Pathog., 9, 2013
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4MBX
| Structure of unliganded B-Lymphotropic Polyomavirus VP1 | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Major Capsid Protein VP1 | 著者 | Khan, Z.M, Neu, U, Schuch, B, Stehle, T. | 登録日 | 2013-08-21 | 公開日 | 2013-12-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structures of B-Lymphotropic Polyomavirus VP1 in Complex with Oligosaccharide Ligands. Plos Pathog., 9, 2013
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4MBZ
| Structure of B-Lymphotropic Polyomavirus VP1 in complex with 3'-sialyllactosamine | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Khan, Z.M, Neu, U, Stehle, T. | 登録日 | 2013-08-21 | 公開日 | 2013-12-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structures of B-Lymphotropic Polyomavirus VP1 in Complex with Oligosaccharide Ligands. Plos Pathog., 9, 2013
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7DFV
| Cryo-EM structure of plant NLR RPP1 tetramer core part | 分子名称: | NAD+ hydrolase (NADase) | 著者 | Ma, S.C, Lapin, D, Liu, L, Sun, Y, Song, W, Zhang, X.X, Logemann, E, Yu, D.L, Wang, J, Jirschitzka, J, Han, Z.F, SchulzeLefert, P, Parker, J.E, Chai, J.J. | 登録日 | 2020-11-10 | 公開日 | 2020-12-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | 主引用文献 | Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme. Science, 370, 2020
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2G99
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5HYX
| Plant peptide hormone receptor RGFR1 in complex with RGF1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PTR-SER-ASN-PRO-GLY-HIS-HIS-PRO-HYP-ARG-HIS-ASN, ... | 著者 | Song, W, Han, Z, Chai, J. | 登録日 | 2016-02-02 | 公開日 | 2017-01-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.596 Å) | 主引用文献 | Signature motif-guided identification of receptors for peptide hormones essential for root meristem growth Cell Res., 26, 2016
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5HZ1
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8WGV
| BA.2(S375) Spike (S6P)/hACE2 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Wei, X, Zhang, Z. | 登録日 | 2023-09-22 | 公開日 | 2024-02-28 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis. Nat.Immunol., 25, 2024
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8WGW
| Local refinement of RBD-ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Wei, X, Zhang, Z. | 登録日 | 2023-09-22 | 公開日 | 2024-02-28 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis. Nat.Immunol., 25, 2024
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9AYF
| Structure of human calcium-sensing receptor in complex with Gi1 (miniGi1) protein in detergent | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ... | 著者 | Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R. | 登録日 | 2024-03-07 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Promiscuous G-protein activation by the calcium-sensing receptor. Nature, 629, 2024
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9AVG
| Structure of human calcium-sensing receptor in complex with chimeric Gs (miniGis) protein in nanodiscs | 分子名称: | (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R. | 登録日 | 2024-03-02 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Promiscuous G-protein activation by the calcium-sensing receptor. Nature, 629, 2024
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9ASB
| Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in nanodiscs | 分子名称: | (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R. | 登録日 | 2024-02-24 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Promiscuous G-protein activation by the calcium-sensing receptor. Nature, 629, 2024
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9AVL
| Structure of human calcium-sensing receptor in complex with Gi3 protein in nanodiscs | 分子名称: | (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R. | 登録日 | 2024-03-04 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Promiscuous G-protein activation by the calcium-sensing receptor. Nature, 629, 2024
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9AXF
| Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in detergent | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ... | 著者 | Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R. | 登録日 | 2024-03-06 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Promiscuous G-protein activation by the calcium-sensing receptor. Nature, 629, 2024
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8WH8
| Structure of DDM1-nucleosome complex in ADP state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, DNA (antisense strand), ... | 著者 | Liu, Y, Zhang, Z, Du, J. | 登録日 | 2023-09-22 | 公開日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation. Nat.Plants, 10, 2024
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8WHA
| Structure of DDM1-nucleosome complex in the ADP-BeFx state with DDM1 bound to SHL2 and SHL-2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Liu, Y, Zhang, Z, Du, J. | 登録日 | 2023-09-22 | 公開日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (4.05 Å) | 主引用文献 | Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation. Nat.Plants, 10, 2024
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8WH9
| Structure of DDM1-nucleosome complex in ADP-BeFx state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Liu, Y, Zhang, Z, Du, J. | 登録日 | 2023-09-22 | 公開日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation. Nat.Plants, 10, 2024
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