3RC0
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![BU of 3rc0 by Molmil](/molmil-images/mine/3rc0) | Human SETD6 in complex with RelA Lys310 peptide | 分子名称: | 1,2-ETHANEDIOL, N-lysine methyltransferase SETD6, S-ADENOSYLMETHIONINE, ... | 著者 | Chang, Y, Levy, D, Horton, J.R, Peng, J, Zhang, X, Gozani, O, Cheng, X. | 登録日 | 2011-03-30 | 公開日 | 2011-05-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling. Nucleic Acids Res., 39, 2011
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6UTU
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![BU of 6utu by Molmil](/molmil-images/mine/6utu) | Crystal structure of minor pseudopilin ternary complex of XcpVWX from the Type 2 secretion system of Pseudomonas aeruginosa in the P3 space group | 分子名称: | CALCIUM ION, Type II secretion system protein I, Type II secretion system protein J, ... | 著者 | Zhang, Y, Wang, S, Jia, Z. | 登録日 | 2019-10-30 | 公開日 | 2020-09-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | In Situ Proteolysis Condition-Induced Crystallization of the XcpVWX Complex in Different Lattices. Int J Mol Sci, 21, 2020
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3QXY
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![BU of 3qxy by Molmil](/molmil-images/mine/3qxy) | Human SETD6 in complex with RelA Lys310 | 分子名称: | 1,2-ETHANEDIOL, N-lysine methyltransferase SETD6, S-ADENOSYLMETHIONINE, ... | 著者 | Chang, Y, Levy, D, Horton, J.R, Peng, J, Zhang, X, Gozani, O, Cheng, X. | 登録日 | 2011-03-02 | 公開日 | 2011-05-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling. Nucleic Acids Res., 39, 2011
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8CZJ
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![BU of 8czj by Molmil](/molmil-images/mine/8czj) | A bacteria Zrt/Irt-like protein in the apo state | 分子名称: | Putative membrane protein, SULFATE ION, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate | 著者 | Zhang, Y, Hu, J. | 登録日 | 2022-05-24 | 公開日 | 2023-02-22 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.751 Å) | 主引用文献 | Structural insights into the elevator-type transport mechanism of a bacterial ZIP metal transporter. Nat Commun, 14, 2023
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3OMW
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![BU of 3omw by Molmil](/molmil-images/mine/3omw) | Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II | 分子名称: | CG14216 | 著者 | Zhang, Y, Zhang, M, Zhang, Y. | 登録日 | 2010-08-27 | 公開日 | 2011-01-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8701 Å) | 主引用文献 | Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue. Biochem.J., 434, 2011
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8E4V
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7BZ2
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![BU of 7bz2 by Molmil](/molmil-images/mine/7bz2) | Cryo-EM structure of the formoterol-bound beta2 adrenergic receptor-Gs protein complex. | 分子名称: | Beta2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhang, Y.N, Yang, F, Ling, S.L, Lv, P, Zhou, Y.X, Fang, W, Sun, W, Shi, P, Tian, C.L. | 登録日 | 2020-04-26 | 公開日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | 主引用文献 | Single-particle cryo-EM structural studies of the beta2AR-Gs complex bound with a full agonist formoterol. Cell Discov, 6, 2020
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3QO2
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![BU of 3qo2 by Molmil](/molmil-images/mine/3qo2) | Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9 | 分子名称: | 1,2-ETHANEDIOL, Histone H3 peptide, M-phase phosphoprotein 8 | 著者 | Chang, Y, Horton, J.R, Bedford, M.T, Zhang, X, Cheng, X. | 登録日 | 2011-02-09 | 公開日 | 2011-04-06 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9: potential effect of phosphorylation on methyl-lysine binding. J.Mol.Biol., 408, 2011
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3OG7
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![BU of 3og7 by Molmil](/molmil-images/mine/3og7) | B-Raf Kinase V600E oncogenic mutant in complex with PLX4032 | 分子名称: | AKAP9-BRAF fusion protein, N-(3-{[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide | 著者 | Zhang, Y, Zhang, K.Y, Zhang, C. | 登録日 | 2010-08-16 | 公開日 | 2010-09-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Nature, 467, 2010
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3OMX
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![BU of 3omx by Molmil](/molmil-images/mine/3omx) | Crystal structure of Ssu72 with vanadate complex | 分子名称: | CG14216, VANADATE ION | 著者 | Zhang, Y, Zhang, M, Zhang, Y. | 登録日 | 2010-08-27 | 公開日 | 2011-01-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3366 Å) | 主引用文献 | Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue. Biochem.J., 434, 2011
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5GSN
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![BU of 5gsn by Molmil](/molmil-images/mine/5gsn) | Tmm in complex with methimazole | 分子名称: | 1-METHYL-1,3-DIHYDRO-2H-IMIDAZOLE-2-THIONE, FLAVIN-ADENINE DINUCLEOTIDE, Flavin-containing monooxygenase, ... | 著者 | Zhang, Y.Z, Li, C.Y. | 登録日 | 2016-08-16 | 公開日 | 2017-01-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.203 Å) | 主引用文献 | Structural mechanism for bacterial oxidation of oceanic trimethylamine into trimethylamine N-oxide Mol. Microbiol., 103, 2017
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1N6G
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![BU of 1n6g by Molmil](/molmil-images/mine/1n6g) | The structure of immature Dengue-2 prM particles | 分子名称: | major envelope protein E | 著者 | Zhang, Y, Corver, J, Chipman, P.R, Zhang, W, Pletnev, S.V, Sedlak, D, Baker, T.S, Strauss, J.H, Kuhn, R.J, Rossmann, M.G. | 登録日 | 2002-11-10 | 公開日 | 2003-06-03 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (16 Å) | 主引用文献 | Structures of Immature flavivirus particles EMBO J., 22, 2003
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1NA4
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![BU of 1na4 by Molmil](/molmil-images/mine/1na4) | The structure of immature Yellow Fever virus particle | 分子名称: | major envelope protein E | 著者 | Zhang, Y, Corver, J, Chipman, P.R, Lenches, E, Zhang, W, Pletnev, S.V, Sedlak, D, Baker, T.S, Strauss, J.H, Kuhn, R.J, Rossmann, M.G. | 登録日 | 2002-11-26 | 公開日 | 2003-12-09 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY | 主引用文献 | Structures of immature flavivirus particles EMBO J., 22, 2003
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7D0A
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![BU of 7d0a by Molmil](/molmil-images/mine/7d0a) | Acinetobacter MlaFEDB complex in ADP-vanadate trapped Vclose conformation | 分子名称: | ABC transporter ATP-binding protein, ADENOSINE-5'-DIPHOSPHATE, Anti-sigma factor antagonist, ... | 著者 | Zhang, Y.Y, Fan, Q.X, Chi, X.M, Zhou, Q, Li, Y.Y. | 登録日 | 2020-09-09 | 公開日 | 2020-12-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM structures of Acinetobacter baumannii glycerophospholipid transporter. Cell Discov, 6, 2020
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7D09
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![BU of 7d09 by Molmil](/molmil-images/mine/7d09) | Acinetobacter MlaFEDB complex in ATP-bound Vtrans2 conformation | 分子名称: | ABC transporter ATP-binding protein, ADENOSINE-5'-TRIPHOSPHATE, Anti-sigma factor antagonist, ... | 著者 | Zhang, Y.Y, Fan, Q.X, Chi, X.M, Zhou, Q, Li, Y.Y. | 登録日 | 2020-09-09 | 公開日 | 2020-12-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM structures of Acinetobacter baumannii glycerophospholipid transporter. Cell Discov, 6, 2020
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1VZT
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![BU of 1vzt by Molmil](/molmil-images/mine/1vzt) | ROLES OF INDIVIDUAL RESIDUES OF ALPHA-1,3 GALACTOSYLTRANSFERASES IN SUBSTRATE BINDING AND CATALYSIS | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ... | 著者 | Zhang, Y, Swaminathan, G.J, Deshpande, A, Natesh, R, Xie, X, Acharya, K.R, Brew, K. | 登録日 | 2004-05-26 | 公開日 | 2005-05-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Roles of Individual Enzyme-Substrate Interactions by Alpha-1,3-Galactosyltransferase in Catalysis and Specificity. Biochemistry, 42, 2003
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5E1R
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8JOO
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![BU of 8joo by Molmil](/molmil-images/mine/8joo) | Crystal structure of cytochrome P450 IkaD from Streptomyces sp. ZJ306, in complex with the substrate ikarugamycin | 分子名称: | (1Z,3E,5S,7R,8R,10R,11R,12S,15R,16S,18Z,25S)-11-ethyl-2-hydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.05,16.07,15.08,12]octacosa-1(2),3,13,18-tetraene-20,27,28-trione, Cytochrome P450, FORMIC ACID, ... | 著者 | Zhang, Y.L, Zhang, L.P, Zhang, C.S. | 登録日 | 2023-06-08 | 公開日 | 2023-11-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates. Angew.Chem.Int.Ed.Engl., 62, 2023
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2ZUC
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4DC2
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![BU of 4dc2 by Molmil](/molmil-images/mine/4dc2) | Structure of PKC in Complex with a Substrate Peptide from Par-3 | 分子名称: | ADENINE, Partitioning defective 3 homolog, Protein kinase C iota type | 著者 | Shang, Y, Wang, C, Yu, J, Zhang, M. | 登録日 | 2012-01-17 | 公開日 | 2012-07-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Substrate recognition mechanism of atypical protein kinase Cs revealed by the structure of PKC iota in complex with a substrate peptide from Par-3 Structure, 20, 2012
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1PQN
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![BU of 1pqn by Molmil](/molmil-images/mine/1pqn) | dominant negative human hDim1 (hDim1 1-128) | 分子名称: | Spliceosomal U5 snRNP-specific 15 kDa protein | 著者 | Zhang, Y.Z, Cheng, H, Gould, K.L, Golemis, E.A, Roder, H. | 登録日 | 2003-06-18 | 公開日 | 2003-08-26 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure, stability and function of hDim1 investigated by NMR, circular
dichroism and mutational analysis Biochemistry, 42, 2003
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7F7G
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![BU of 7f7g by Molmil](/molmil-images/mine/7f7g) | a linear Peptide Inhibitors in complex with GK domain | 分子名称: | DLG4 GK domain, UNK-ARG-ILE-ARG-ARG-ASP-GLU-TYR-LEU-LYS-ALA-ILE-GLN-UNK | 著者 | Shang, Y, Huang, X, Li, X, Zhang, M. | 登録日 | 2021-06-29 | 公開日 | 2022-02-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.446 Å) | 主引用文献 | Entropy of stapled peptide inhibitors in free state is the major contributor to the improvement of binding affinity with the GK domain. Rsc Chem Biol, 2, 2021
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3OPW
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![BU of 3opw by Molmil](/molmil-images/mine/3opw) | Crystal Structure of the Rph1 catalytic core | 分子名称: | DNA damage-responsive transcriptional repressor RPH1 | 著者 | Chang, Y, Wu, J, Tong, X, Zhou, J, Ding, J. | 登録日 | 2010-09-02 | 公開日 | 2010-12-22 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism Biochem.J., 433, 2011
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7F7I
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![BU of 7f7i by Molmil](/molmil-images/mine/7f7i) | Stapled Peptide Inhibitor in complex with PSD95 GK domain | 分子名称: | ACE-ARG-ILE-ARG-ARG-ASP-GLU-TYR-LEU-LYZ-ALA-ILE-GLN-NH2, Disks large homolog 4 | 著者 | Shang, Y, Huang, X, Li, X, Zhang, M. | 登録日 | 2021-06-29 | 公開日 | 2022-04-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.595 Å) | 主引用文献 | Entropy of stapled peptide inhibitors in free state is the major contributor to the improvement of binding affinity with the GK domain. Rsc Chem Biol, 2, 2021
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3OPT
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![BU of 3opt by Molmil](/molmil-images/mine/3opt) | Crystal structure of the Rph1 catalytic core with a-ketoglutarate | 分子名称: | 2-OXOGLUTARIC ACID, DNA damage-responsive transcriptional repressor RPH1, NICKEL (II) ION | 著者 | Chang, Y, Wu, J, Tong, X, Zhou, J, Ding, J. | 登録日 | 2010-09-02 | 公開日 | 2010-12-22 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism Biochem.J., 433, 2011
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