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PDB: 687 results

7KDW
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BU of 7kdw by Molmil
Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to Compound 6 (HZ01052)
Descriptor: 1,2-ETHANEDIOL, Nucleosome-remodeling factor subunit BPTF, cyclopropyl[7-({2-[(prop-2-yn-1-yl)amino]pyrimidin-4-yl}amino)-3,4-dihydroquinolin-1(2H)-yl]methanone
Authors:Chan, A, Schonbrunn, E.
Deposit date:2020-10-09
Release date:2020-12-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development
Organic and Biomolecular Chemistry, 18(27), 2020
7KDZ
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BU of 7kdz by Molmil
Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to TP-238
Descriptor: 1,2-ETHANEDIOL, 6-{4-[3-(dimethylamino)propoxy]phenyl}-2-(methylsulfonyl)-N-[3-(1H-pyrazol-1-yl)propyl]pyrimidin-4-amine, Nucleosome-remodeling factor subunit BPTF
Authors:Chan, A, Schonbrunn, E.
Deposit date:2020-10-09
Release date:2020-12-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development
Organic & Biomolecular Chemistry, 18(27), 2020
7K6R
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BU of 7k6r by Molmil
Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to GSK4027
Descriptor: 1,2-ETHANEDIOL, 4-bromo-2-methyl-5-[[(3~{R},5~{R})-1-methyl-5-phenyl-piperidin-3-yl]amino]pyridazin-3-one, Nucleosome-remodeling factor subunit BPTF
Authors:Chan, A, Schonbrunn, E.
Deposit date:2020-09-21
Release date:2020-12-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development.
Org.Biomol.Chem., 18, 2020
2GXB
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BU of 2gxb by Molmil
Crystal Structure of The Za Domain bound to Z-RNA
Descriptor: 5'-R(P*(DU)P*CP*GP*CP*GP*CP*G)-3', Double-stranded RNA-specific adenosine deaminase, SODIUM ION
Authors:Athanasiadis, A, Placido, D, Rich, A.
Deposit date:2006-05-08
Release date:2007-05-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:A Left-Handed RNA Double Helix Bound by the Zalpha Domain of the RNA-Editing Enzyme ADAR1.
Structure, 15, 2007
1I9S
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BU of 1i9s by Molmil
CRYSTAL STRUCTURE OF THE RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME
Descriptor: CACODYLATE ION, ISOPROPYL ALCOHOL, MAGNESIUM ION, ...
Authors:Changela, A, Ho, C.K, Martins, A, Shuman, S, Mondragon, A.
Deposit date:2001-03-20
Release date:2001-05-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme.
EMBO J., 20, 2001
1I7D
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BU of 1i7d by Molmil
NONCOVALENT COMPLEX OF E.COLI DNA TOPOISOMERASE III WITH AN 8-BASE SINGLE-STRANDED DNA OLIGONUCLEOTIDE
Descriptor: 5'-D(*CP*GP*CP*AP*AP*CP*TP*T)-3', CHLORIDE ION, DNA TOPOISOMERASE III, ...
Authors:Changela, A, DiGate, R.J, Mondragon, A.
Deposit date:2001-03-08
Release date:2001-06-29
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of a complex of a type IA DNA topoisomerase with a single-stranded DNA molecule.
Nature, 411, 2001
1I9T
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BU of 1i9t by Molmil
CRYSTAL STRUCTURE OF THE OXIDIZED RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME
Descriptor: CACODYLATE ION, ISOPROPYL ALCOHOL, MAGNESIUM ION, ...
Authors:Changela, A, Ho, C.K, Martins, A, Shuman, S, Mondragon, A.
Deposit date:2001-03-20
Release date:2001-05-23
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme.
EMBO J., 20, 2001
3RSC
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BU of 3rsc by Molmil
Crystal Structure of CalG2, Calicheamicin Glycosyltransferase, TDP and calicheamicin T0 bound form
Descriptor: CalG2, Calicheamicin T0, PHOSPHATE ION, ...
Authors:Chang, A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2011-05-02
Release date:2011-08-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Proc.Natl.Acad.Sci.USA, 108, 2011
5XMX
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BU of 5xmx by Molmil
Co-crystal structure of Inhibitor compound in complex with human PPARdelta LBD
Descriptor: (E)-6-[2-[[[4-(furan-2-yl)phenyl]carbonyl-methyl-amino]methyl]phenoxy]-4-methyl-hex-4-enoic acid, Peroxisome proliferator-activated receptor delta
Authors:Lakshminarasimhan, A, Rani, S.T, Senaiar, R.S, Krishnamurthy, N.
Deposit date:2017-05-16
Release date:2018-05-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Novel highly selective peroxisome proliferator-activated receptor delta (PPAR delta) modulators with pharmacokinetic properties suitable for once-daily oral dosing.
Bioorg. Med. Chem. Lett., 27, 2017
1YN9
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BU of 1yn9 by Molmil
Crystal structure of baculovirus RNA 5'-phosphatase complexed with phosphate
Descriptor: PHOSPHATE ION, polynucleotide 5'-phosphatase
Authors:Changela, A, Martins, A, Shuman, S, Mondragon, A.
Deposit date:2005-01-24
Release date:2005-02-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of baculovirus RNA triphosphatase complexed with phosphate
J.Biol.Chem., 280, 2005
6IF7
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BU of 6if7 by Molmil
Crystal Structure of AA10 Lytic Polysaccharide Monooxygenase from Tectaria macrodonta
Descriptor: COPPER (II) ION, Chitin binding protein, GLYCEROL, ...
Authors:Archana, A, Yadav, S.K, Singh, P.K, Vasudev, P.G.
Deposit date:2018-09-18
Release date:2019-04-24
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Insecticidal fern protein Tma12 is possibly a lytic polysaccharide monooxygenase.
Planta, 249, 2019
2H3H
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BU of 2h3h by Molmil
Crystal structure of the liganded form of Thermotoga maritima glucose binding protein
Descriptor: Sugar ABC transporter, periplasmic sugar-binding protein, beta-D-glucopyranose
Authors:Changela, A, Tian, Y.
Deposit date:2006-05-22
Release date:2007-05-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose-binding protein.
Protein Sci., 16, 2007
4AP4
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BU of 4ap4 by Molmil
Rnf4 - ubch5a - ubiquitin heterotrimeric complex
Descriptor: E3 UBIQUITIN LIGASE RNF4, UBIQUITIN C, UBIQUITIN-CONJUGATING ENZYME E2 D1, ...
Authors:Plechanovova, A, Hay, R.T, Tatham, M.H, Jaffray, E, Naismith, J.H.
Deposit date:2012-03-30
Release date:2012-07-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structure of a Ring E3 Ligase and Ubiquitin-Loaded E2 Primed for Catalysis
Nature, 489, 2012
2O5C
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BU of 2o5c by Molmil
Structure of E. coli topoisomerase III in complex with an 8-base single stranded oligonucleotide. Frozen in glucose pH 5.5
Descriptor: 5'-D(*CP*GP*CP*AP*AP*CP*TP*T)-3', CHLORIDE ION, DNA topoisomerase 3, ...
Authors:Changela, A, DiGate, R.J, Mondragon, A.
Deposit date:2006-12-05
Release date:2007-04-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Studies of E. coli Topoisomerase III-DNA Complexes Reveal a Novel Type IA Topoisomerase-DNA Conformational Intermediate.
J.Mol.Biol., 368, 2007
2O19
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BU of 2o19 by Molmil
Structure of E. coli topoisomersae III in complex with an 8-base single stranded oligonucleotide. Frozen in glycerol at pH 5.5
Descriptor: 5'-D(*CP*GP*CP*AP*AP*CP*TP*T)-3', ACETIC ACID, CHLORIDE ION, ...
Authors:Changela, A, DiGate, R, Mondragon, A.
Deposit date:2006-11-28
Release date:2007-04-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural Studies of E. coli Topoisomerase III-DNA Complexes Reveal a Novel Type IA Topoisomerase-DNA Conformational Intermediate.
J.Mol.Biol., 368, 2007
2O54
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BU of 2o54 by Molmil
Structure of E. coli topoisomerase III in complex with an 8-base single stranded oligonucleotide. Frozen in glycerol at pH 7.0
Descriptor: 5'-D(*CP*GP*CP*AP*AP*CP*TP*T)-3', ACETIC ACID, CHLORIDE ION, ...
Authors:Changela, A, Digate, R.J, Mondragon, A.
Deposit date:2006-12-05
Release date:2007-04-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Studies of E. coli Topoisomerase III-DNA Complexes Reveal a Novel Type IA Topoisomerase-DNA Conformational Intermediate.
J.Mol.Biol., 368, 2007
2O5E
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BU of 2o5e by Molmil
Structure of E. coli topoisomerase III in complex with an 8-base single stranded oligonucleotide. Frozen in glucose pH 7.0
Descriptor: 5'-D(*CP*GP*CP*AP*AP*CP*TP*T)-3', CHLORIDE ION, DNA topoisomerase 3, ...
Authors:Changela, A, DiGate, R.J, Mondragon, A.
Deposit date:2006-12-05
Release date:2007-04-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Studies of E. coli Topoisomerase III-DNA Complexes Reveal a Novel Type IA Topoisomerase-DNA Conformational Intermediate.
J.Mol.Biol., 368, 2007
9CZ1
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BU of 9cz1 by Molmil
Cryo-EM structure of a 'hat' portion of FtsH.HflK.HflC complex
Descriptor: Modulator of FtsH protease HflC, Modulator of FtsH protease HflK
Authors:Ghanbarpour, A, Sauer, R.T, Davis, J.H.
Deposit date:2024-08-03
Release date:2024-11-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of a 'hat' portion of FtsH.HflK.HflC complex
To Be Published
1XMK
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BU of 1xmk by Molmil
The Crystal structure of the Zb domain from the RNA editing enzyme ADAR1
Descriptor: CADMIUM ION, CHLORIDE ION, Double-stranded RNA-specific adenosine deaminase, ...
Authors:Athanasiadis, A, Placido, D, Maas, S, Brown II, B.A, Lowenhaupt, K, Rich, A.
Deposit date:2004-10-03
Release date:2005-08-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:The Crystal Structure of the Z[beta] Domain of the RNA-editing Enzyme ADAR1 Reveals Distinct Conserved Surfaces Among Z-domains.
J.Mol.Biol., 351, 2005
9CZ2
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BU of 9cz2 by Molmil
Cryo-EM structure of a nautilus-like HflK/C assembly in complex with FtsH AAA protease
Descriptor: ATP-dependent zinc metalloprotease FtsH, Modulator of FtsH protease HflC, Modulator of FtsH protease HflK
Authors:Ghanbarpour, A, Sauer, R.T, Davis, J.H.
Deposit date:2024-08-03
Release date:2024-11-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-EM structure of a nautilus-like HflK/C assembly in complex with FtsH AAA protease
To Be Published
3TSR
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BU of 3tsr by Molmil
X-ray structure of mouse ribonuclease inhibitor complexed with mouse ribonuclease 1
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ribonuclease inhibitor, ...
Authors:Chang, A, Lomax, J.E, Bingman, C.A, Raines, R.T, Phillips Jr, G.N.
Deposit date:2011-09-13
Release date:2012-09-19
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.1999 Å)
Cite:Functional evolution of ribonuclease inhibitor: insights from birds and reptiles.
J.Mol.Biol., 426, 2014
3TOS
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BU of 3tos by Molmil
Crystal Structure of CalS11, Calicheamicin Methyltransferase
Descriptor: 1,2-ETHANEDIOL, CalS11, GLUTAMIC ACID, ...
Authors:Chang, A, Aceti, D.J, Beebe, E.T, Makino, S.-I, Wrobel, R.L, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2011-09-06
Release date:2011-10-05
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal Structure of CalS11, Calicheamicin methyltransferase
To be Published
2O59
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BU of 2o59 by Molmil
Structure of E. coli topoisomerase III in complex with an 8-base single stranded oligonucleotide. Frozen in glycerol pH 8.0
Descriptor: 5'-D(*CP*GP*CP*AP*AP*CP*TP*T)-3', ACETIC ACID, CHLORIDE ION, ...
Authors:Changela, A, DiGate, R.J, Mondragon, A.
Deposit date:2006-12-05
Release date:2007-04-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Studies of E. coli Topoisomerase III-DNA Complexes Reveal a Novel Type IA Topoisomerase-DNA Conformational Intermediate.
J.Mol.Biol., 368, 2007
4JMQ
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BU of 4jmq by Molmil
Crystal structure of pb9: The Dit of bacteriophage T5.
Descriptor: Bacteriophage T5 distal tail protein
Authors:Flayhan, A, Vellieux, F.M.D, Girard, E, Maury, O, Boulanger, P, Breyton, C.
Deposit date:2013-03-14
Release date:2013-11-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.895 Å)
Cite:Crystal Structure of pb9, the Distal Tail Protein of Bacteriophage T5: a Conserved Structural Motif among All Siphophages.
J.Virol., 88, 2014
1IAZ
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BU of 1iaz by Molmil
EQUINATOXIN II
Descriptor: EQUINATOXIN II, SULFATE ION
Authors:Athanasiadis, A, Anderluh, G, Macek, P, Turk, D.
Deposit date:2001-03-24
Release date:2001-04-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the soluble form of equinatoxin II, a pore-forming toxin from the sea anemone Actinia equina.
Structure, 9, 2001

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