3RSC
Crystal Structure of CalG2, Calicheamicin Glycosyltransferase, TDP and calicheamicin T0 bound form
Summary for 3RSC
Entry DOI | 10.2210/pdb3rsc/pdb |
Related | 3IAA |
Descriptor | CalG2, THYMIDINE-5'-DIPHOSPHATE, Calicheamicin T0, ... (5 entities in total) |
Functional Keywords | tdp, enediyne, structural genomics, psi-2, protein structure initiative, center for eukaryotic structural genomics, cesg, glycosyltransferase, transferase-antibiotic complex, enzyme discovery for natural product biosynthesis, natpro, transferase/antibiotic |
Biological source | Micromonospora echinospora |
Total number of polymer chains | 2 |
Total formula weight | 94010.23 |
Authors | Chang, A.,Helmich, K.E.,Singh, S.,Bingman, C.A.,Thorson, J.S.,Phillips Jr., G.N.,Center for Eukaryotic Structural Genomics (CESG),Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2011-05-02, release date: 2011-08-10, Last modification date: 2017-11-08) |
Primary citation | Chang, A.,Singh, S.,Helmich, K.E.,Goff, R.D.,Bingman, C.A.,Thorson, J.S.,Phillips, G.N. Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity. Proc.Natl.Acad.Sci.USA, 108:17649-17654, 2011 Cited by PubMed: 21987796DOI: 10.1073/pnas.1108484108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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