6W9Z
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![BU of 6w9z by Molmil](/molmil-images/mine/6w9z) | De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release | 分子名称: | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, De novo designed receptor transmembrane domain ProMP C2.1 | 著者 | Call, M.J, Call, M.E, Chandler, N.J, Nguyen, J.V, Trenker, R. | 登録日 | 2020-03-24 | 公開日 | 2021-03-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release To Be Published
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6WA0
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6W9Y
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![BU of 6w9y by Molmil](/molmil-images/mine/6w9y) | De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release | 分子名称: | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, De novo designed receptor transmembrane domain proMP 1.2 | 著者 | Call, M.J, Call, M.E, Chandler, N.J, Nguyen, J.V, Trenker, R. | 登録日 | 2020-03-24 | 公開日 | 2021-03-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release To Be Published
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1XHO
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![BU of 1xho by Molmil](/molmil-images/mine/1xho) | Chorismate mutase from Clostridium thermocellum Cth-682 | 分子名称: | Chorismate mutase, UNKNOWN ATOM OR ION | 著者 | Xu, H, Chen, L, Lee, D, Habel, J.E, Nguyen, J, Chang, S.-H, Kataeva, I, Chang, J, Zhao, M, Yang, H, Horanyi, P, Florence, Q, Tempel, W, Zhou, W, Lin, D, Zhang, H, Praissman, J, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Ljungdahl, L, Liu, Z.-J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2004-09-20 | 公開日 | 2004-11-23 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Away from the edge II: in-house Se-SAS phasing with chromium radiation. Acta Crystallogr.,Sect.D, 61, 2005
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1XMA
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![BU of 1xma by Molmil](/molmil-images/mine/1xma) | Structure of a transcriptional regulator from Clostridium thermocellum Cth-833 | 分子名称: | MERCURY (II) ION, Predicted transcriptional regulator, UNKNOWN ATOM OR ION | 著者 | Yang, H, Chen, L, Lee, D, Habel, J, Nguyen, J, Chang, S.-H, Kataeva, I, Xu, H, Chang, J, Zhao, M, Horanyi, P, Florence, Q, Zhou, W, Tempel, W, Lin, D, Praissman, J, Zhang, H, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Ljungdahl, L, Liu, Z.-J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2004-10-01 | 公開日 | 2004-12-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Structure of a transcriptional regulator from Clostridium thermocellum Cth-833 To be published
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1XRG
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![BU of 1xrg by Molmil](/molmil-images/mine/1xrg) | Conserved hypothetical protein from Clostridium thermocellum Cth-2968 | 分子名称: | Putative translation initiation inhibitor, yjgF family, UNKNOWN ATOM OR ION | 著者 | Zhao, M, Chang, J, Habel, J, Kataeva, I, Xu, H, Chen, L, Lee, D, Nguyen, J, Chang, S.-H, Horanyi, P, Florence, Q, Zhou, W, Tempel, W, Lin, D, Zhang, H, Arendall III, W.B, Ljundahl, L, Liu, Z.-J, Rose, J, Richardson, J.S, Richardson, D.C, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2004-10-14 | 公開日 | 2004-12-14 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Conserved hypothetical protein from Clostridium thermocellum Cth-2968 To be published
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1YBY
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![BU of 1yby by Molmil](/molmil-images/mine/1yby) | Conserved hypothetical protein Cth-95 from Clostridium thermocellum | 分子名称: | Translation elongation factor P, UNKNOWN ATOM OR ION | 著者 | Zhao, M, Zhou, W, Chang, J, Habel, J, Kataeva, I, Xu, H, Chen, L, Lee, D, Nguyen, J, Chang, S.-H, Horanyi, P, Florence, Q, Tempel, W, Lin, D, Zhang, H, Ljundahl, L, Liu, Z.-J, Rose, J, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2004-12-21 | 公開日 | 2005-02-01 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Conserved hypothetical protein Cth-95 from Clostridium thermocellum To be published
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1YBX
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![BU of 1ybx by Molmil](/molmil-images/mine/1ybx) | Conserved hypothetical protein Cth-383 from Clostridium thermocellum | 分子名称: | Conserved hypothetical protein, UNKNOWN ATOM OR ION | 著者 | Tempel, W, Chang, J, Zhao, M, Habel, J, Kataeva, I, Xu, H, Chen, L, Lee, D, Nguyen, J, Chang, S.-H, Horanyi, P, Florence, Q, Zhou, W, Lin, D, Zhang, H, Ljundahl, L, Liu, Z.-J, Rose, J, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2004-12-21 | 公開日 | 2005-02-01 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Conserved hypothetical protein Cth-383 from Clostridium thermocellum To be published
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1ZD0
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![BU of 1zd0 by Molmil](/molmil-images/mine/1zd0) | Crystal structure of Pfu-542154 conserved hypothetical protein | 分子名称: | MAGNESIUM ION, METHANOL, UNKNOWN ATOM OR ION, ... | 著者 | Habel, J.E, Liu, Z.J, Horanyi, P.S, Florence, Q.J.T, Tempel, W, Zhou, W, Chen, L, Lee, D, Nguyen, J, Chang, S.H, Bereton, P, Izumi, M, Jenny Jr, F.E, Poole II, F.L, Shah, C, Sugar, F.J, Adams, M.W.W, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2005-04-13 | 公開日 | 2005-05-17 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of Pfu-542154 conserved hypothetical protein To be Published
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4PHU
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![BU of 4phu by Molmil](/molmil-images/mine/4phu) | Crystal structure of Human GPR40 bound to allosteric agonist TAK-875 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DIMETHYL SULFOXIDE, Free fatty acid receptor 1,Lysozyme, ... | 著者 | Srivastava, A, Yano, J.K, Hirozane, Y, Kefala, G, Snell, G, Lane, W, Gruswitz, F, Ivetac, A, Aertgeerts, K, Nguyen, J, Jennings, A, Okada, K. | 登録日 | 2014-05-07 | 公開日 | 2014-07-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.332 Å) | 主引用文献 | High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875. Nature, 513, 2014
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3LIN
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![BU of 3lin by Molmil](/molmil-images/mine/3lin) | crystal structure of HTLV protease complexed with the inhibitor, KNI-10562 | 分子名称: | N-[(2S,3S)-4-{(4R)-4-[(2,2-dimethylpropyl)carbamoyl]-5,5-dimethyl-1,3-thiazolidin-3-yl}-3-hydroxy-4-oxo-1-phenylbutan-2-yl]-N~2~-{(2S)-2-[(methoxycarbonyl)amino]-2-phenylacetyl}-3-methyl-L-valinamide, Protease | 著者 | Satoh, T, Li, M, Nguyen, J, Kiso, Y, Wlodawer, A, Gustchina, A. | 登録日 | 2010-01-25 | 公開日 | 2010-07-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease. J.Mol.Biol., 401, 2010
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3LIY
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![BU of 3liy by Molmil](/molmil-images/mine/3liy) | crystal structure of HTLV protease complexed with Statine-containing peptide inhibitor | 分子名称: | DI(HYDROXYETHYL)ETHER, Protease, statine-containing inhibitor | 著者 | Satoh, T, Li, M, Nguyen, J, Kiso, Y, Wlodawer, A, Gustchina, A. | 登録日 | 2010-01-25 | 公開日 | 2010-07-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease. J.Mol.Biol., 401, 2010
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7TB6
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![BU of 7tb6 by Molmil](/molmil-images/mine/7tb6) | Structure of S. maltophilia CapW | 分子名称: | S. maltophilia CapW, SULFATE ION | 著者 | Blankenchip, C.L, Nguyen, J.V, Lau, R.K, Ye, Q, Corbett, K.D. | 登録日 | 2021-12-21 | 公開日 | 2022-01-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Control of bacterial immune signaling by a WYL domain transcription factor. Nucleic Acids Res., 50, 2022
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7TB5
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![BU of 7tb5 by Molmil](/molmil-images/mine/7tb5) | Structure of P. aeruginosa PA17 CapW | 分子名称: | SULFATE ION, WYL domain-containing protein | 著者 | Blankenchip, C.L, Nguyen, J.V, Lau, R.K, Ye, Q, Corbett, K.D. | 登録日 | 2021-12-21 | 公開日 | 2022-01-19 | 最終更新日 | 2022-06-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Control of bacterial immune signaling by a WYL domain transcription factor. Nucleic Acids Res., 50, 2022
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4DT5
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![BU of 4dt5 by Molmil](/molmil-images/mine/4dt5) | Crystal Structure of Rhagium inquisitor Antifreeze Protein | 分子名称: | Antifreeze protein, GLYCEROL, SULFATE ION | 著者 | Meng, W, Nguyen, J.B, Hakim, A, Thakral, D, Zhu, D.F. | 登録日 | 2012-02-20 | 公開日 | 2013-03-13 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Crystal structure of an insect antifreeze protein and its implications for ice binding. J.Biol.Chem., 288, 2013
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2A4K
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![BU of 2a4k by Molmil](/molmil-images/mine/2a4k) | 3-Oxoacyl-[acyl carrier protein] reductase from Thermus thermophilus TT0137 | 分子名称: | 3-oxoacyl-[acyl carrier protein] reductase, UNKNOWN ATOM OR ION | 著者 | Zhou, W, Ebihara, A, Tempel, W, Yokoyama, S, Chen, L, Kuramitsu, S, Nguyen, J, Chang, S.-H, Liu, Z.-J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-06-29 | 公開日 | 2006-01-10 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | 3-Oxoacyl-[acyl carrier protein] reductase from Thermus thermophilus TT0137 To be Published
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3LIQ
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![BU of 3liq by Molmil](/molmil-images/mine/3liq) | Crystal Structure of HTLV protease complexed with the inhibitor, KNI-10673 | 分子名称: | (4R)-3-[(2S,3S)-3-[[(2S)-2-[[(2S)-2-azanyl-2-phenyl-ethanoyl]amino]-3,3-dimethyl-butanoyl]amino]-2-hydroxy-4-phenyl-but anoyl]-5,5-dimethyl-N-(2-methylpropyl)-1,3-thiazolidine-4-carboxamide, Protease | 著者 | Satoh, T, Li, M, Nguyen, J, Kiso, Y, Wlodawer, A, Gustchina, A. | 登録日 | 2010-01-25 | 公開日 | 2010-07-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease. J.Mol.Biol., 401, 2010
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3LIT
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![BU of 3lit by Molmil](/molmil-images/mine/3lit) | The crystal structure of htlv protease complexed with the inhibitor KNI-10681 | 分子名称: | (4R)-3-[(2S,3S)-3-[[(2S)-2-[[(2S)-2-azanyl-2-phenyl-ethanoyl]amino]-3,3-dimethyl-butanoyl]amino]-2-hydroxy-4-phenyl-but anoyl]-5,5-dimethyl-N-[(2R)-3-methylbutan-2-yl]-1,3-thiazolidine-4-carboxamide, Protease | 著者 | Satoh, T, Li, M, Nguyen, J, Kiso, Y, Wlodawer, A, Gustchina, A. | 登録日 | 2010-01-25 | 公開日 | 2010-07-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease. J.Mol.Biol., 401, 2010
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1SHL
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![BU of 1shl by Molmil](/molmil-images/mine/1shl) | CASPASE-7 IN COMPLEX WITH FICA ALLOSTERIC INHIBITOR | 分子名称: | 5-FLUORO-1H-INDOLE-2-CARBOXYLIC ACID-(2-MERCAPTO-ETHYL)-AMIDE, Caspase-7 | 著者 | Hardy, J.A, Lam, J, Nguyen, J.T, O'Brien, T, Wells, J.A. | 登録日 | 2004-02-25 | 公開日 | 2004-08-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Discovery of an allosteric site in the caspases Proc.Natl.Acad.Sci.USA, 101, 2004
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3LIV
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![BU of 3liv by Molmil](/molmil-images/mine/3liv) | crystal structure of HTLV protease complexed with the inhibitor KNI-10683 | 分子名称: | (4R)-3-[(2S,3S)-3-[[(2S)-2-[[(2S)-2-azanyl-2-phenyl-ethanoyl]amino]-3,3-dimethyl-butanoyl]amino]-2-hydroxy-4-phenyl-but anoyl]-N-[(2R)-3,3-dimethylbutan-2-yl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide, Protease | 著者 | Satoh, T, Li, M, Nguyen, J, Kiso, Y, Wlodawer, A, Gustchina, A. | 登録日 | 2010-01-25 | 公開日 | 2010-07-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease. J.Mol.Biol., 401, 2010
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1SHJ
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![BU of 1shj by Molmil](/molmil-images/mine/1shj) | Caspase-7 in complex with DICA allosteric inhibitor | 分子名称: | 2-(2,4-DICHLORO-PHENOXY)-N-(2-MERCAPTO-ETHYL)-ACETAMIDE, Caspase-7, SULFATE ION | 著者 | Hardy, J.A, Lam, J, Nguyen, J.T, O'Brien, T, Wells, J.A. | 登録日 | 2004-02-25 | 公開日 | 2004-08-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery of an allosteric site in the caspases Proc.Natl.Acad.Sci.USA, 101, 2004
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4DLO
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![BU of 4dlo by Molmil](/molmil-images/mine/4dlo) | Crystal structure of the GAIN and HormR domains of brain angiogenesis inhibitor 3 (BAI3) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Brain-specific angiogenesis inhibitor 3, ... | 著者 | Arac, D, Boucard, A.A, Bolliger, M.F, Nguyen, J, Soltis, M, Sudhof, T.C, Brunger, A.T. | 登録日 | 2012-02-06 | 公開日 | 2012-02-22 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis. Embo J., 31, 2012
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4DLQ
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![BU of 4dlq by Molmil](/molmil-images/mine/4dlq) | Crystal structure of the GAIN and HormR domains of CIRL 1/Latrophilin 1 (CL1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | 著者 | Arac, D, Boucard, A.A, Bolliger, M.F, Nguyen, J, Soltis, M, Sudhof, T.C, Brunger, A.T. | 登録日 | 2012-02-06 | 公開日 | 2012-02-22 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis. Embo J., 31, 2012
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3LIX
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![BU of 3lix by Molmil](/molmil-images/mine/3lix) | crystal structure of htlv protease complexed with the inhibitor KNI-10729 | 分子名称: | N-{(1S,2S)-1-benzyl-3-[(4R)-5,5-dimethyl-4-{[(1R)-1,2,2-trimethylpropyl]carbamoyl}-1,3-thiazolidin-3-yl]-2-hydroxy-3-oxopropyl}-3-methyl-N~2~-{(2S)-2-[(morpholin-4-ylacetyl)amino]-2-phenylacetyl}-L-valinamide, Protease, ZINC ION | 著者 | Satoh, T, Li, M, Nguyen, J, Kiso, Y, Wlodawer, A, Gustchina, A. | 登録日 | 2010-01-25 | 公開日 | 2010-07-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease. J.Mol.Biol., 401, 2010
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