6PLP
 
 | | CryoEM structure of zebra fish alpha-1 glycine receptor YGF mutant bound with GABA in SMA, desensitized state | | Descriptor: | GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Yu, J, Zhu, H, Gouaux, E. | | Deposit date: | 2019-07-01 | | Release date: | 2021-02-10 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
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6PM6
 | | CryoEM structure of zebra fish alpha-1 glycine receptor bound with Glycine in SMA, open state | | Descriptor: | GLYCINE, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Yu, J, Zhu, H, Gouaux, E. | | Deposit date: | 2019-07-01 | | Release date: | 2021-02-10 | | Last modified: | 2021-08-25 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
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6PLW
 | | CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, super-open state | | Descriptor: | GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Yu, J, Zhu, H, Gouaux, E. | | Deposit date: | 2019-07-01 | | Release date: | 2021-02-10 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
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3TT1
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7MGW
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6PXD
 | | CryoEM structure of zebra fish alpha-1 glycine receptor, Apo state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glycine receptor subunit alphaZ1 | | Authors: | Du, J, Lu, W, Gouaux, E. | | Deposit date: | 2019-07-25 | | Release date: | 2021-02-10 | | Last modified: | 2022-08-24 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
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3USJ
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3USK
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3USL
 | | Crystal Structure of LeuT bound to L-selenomethionine in space group C2 from lipid bicelles | | Descriptor: | ACETATE ION, IODIDE ION, PHOSPHOCHOLINE, ... | | Authors: | Wang, H, Elferich, J, Gouaux, E. | | Deposit date: | 2011-11-23 | | Release date: | 2012-01-11 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
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7LI9
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7LIA
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7LI8
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7LI7
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7LI6
 | | apo SERT reconstituted in lipid nanodisc in KCl | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ... | | Authors: | Yang, D, Gouaux, E. | | Deposit date: | 2021-01-26 | | Release date: | 2021-12-15 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
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3USO
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3USI
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7MLV
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7MLU
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7MLY
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7LDE
 | | native AMPA receptor | | Descriptor: | 11B8 scFv, 15F1 Fab heavy chain, 15F1 Fab light chain, ... | | Authors: | Yu, J, Rao, P, Gouaux, E. | | Deposit date: | 2021-01-13 | | Release date: | 2021-05-12 | | Last modified: | 2021-06-30 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition.
Nature, 594, 2021
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7LEP
 | | The composite LBD-TMD structure combined from all hippocampal AMPAR subtypes at 3.25 Angstrom resolution | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 6-[2-chloro-6-(trifluoromethoxy)phenyl]-1H-benzimidazol-2-ol, DECANE, ... | | Authors: | Yu, J, Rao, P, Gouaux, E. | | Deposit date: | 2021-01-14 | | Release date: | 2021-05-12 | | Last modified: | 2021-06-30 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition.
Nature, 594, 2021
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3USM
 | | Crystal Structure of LeuT bound to L-selenomethionine in space group C2 from lipid bicelles (collected at 1.2 A) | | Descriptor: | IODIDE ION, PHOSPHOCHOLINE, SELENOMETHIONINE, ... | | Authors: | Wang, H, Elferich, J, Gouaux, E. | | Deposit date: | 2011-11-23 | | Release date: | 2012-01-11 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (3.008 Å) | | Cite: | Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
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3USP
 | | Crystal structure of LeuT in heptyl-beta-D-Selenoglucoside | | Descriptor: | CHLORIDE ION, LEUCINE, SODIUM ION, ... | | Authors: | Wang, H, Elferich, J, Gouaux, E. | | Deposit date: | 2011-11-23 | | Release date: | 2012-01-11 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
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3TT3
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3TU0
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