Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 176 results
7KMB
DownloadVisualize
BU of 7kmb by Molmil
ACE2-RBD Focused Refinement Using Symmetry Expansion of Applied C3 for Triple ACE2-bound SARS-CoV-2 Trimer Spike at pH 7.4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Gorman, J, Kwong, P.D, Shapiro, L.
Deposit date:2020-11-02
Release date:2020-12-09
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
7KNH
DownloadVisualize
BU of 7knh by Molmil
Cryo-EM Structure of Double ACE2-Bound SARS-CoV-2 Trimer Spike at pH 5.5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L.
Deposit date:2020-11-04
Release date:2020-12-16
Last modified:2021-12-15
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
7KMS
DownloadVisualize
BU of 7kms by Molmil
Cryo-EM structure of triple ACE2-bound SARS-CoV-2 trimer spike at pH 7.4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Gorman, J, Kwong, P.D, Shapiro, L.
Deposit date:2020-11-03
Release date:2020-12-09
Last modified:2021-12-15
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
7KMZ
DownloadVisualize
BU of 7kmz by Molmil
Cryo-EM structure of double ACE2-bound SARS-CoV-2 trimer Spike at pH 7.4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Gorman, J, Kwong, P.D, Shapiro, L.
Deposit date:2020-11-03
Release date:2020-12-09
Last modified:2021-12-15
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
7L0L
DownloadVisualize
BU of 7l0l by Molmil
Cryo-EM structure of the VRC316 clinical trial, vaccine-elicited, human antibody 316-310-1B11 in complex with an H2 CAN05 HA trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 316-310-1B11 Heavy Chain, 316-310-1B11 Light Chain, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2020-12-11
Release date:2021-11-03
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination.
Nat Med, 28, 2022
5VGJ
DownloadVisualize
BU of 5vgj by Molmil
Crystal Structure of the Human Fab VRC38.01, an HIV-1 V1V2-Directed Neutralizing Antibody Isolated from Donor N90, bound to a scaffolded WITO V1V2 domain
Descriptor: 1FD6-V1V2-WITO, 2-acetamido-2-deoxy-beta-D-glucopyranose, VRC38.01 Fab Heavy Chain, ...
Authors:Gorman, J, Li, J, Kwong, P.D.
Deposit date:2017-04-11
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.456 Å)
Cite:Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop.
Immunity, 46, 2017
6DE7
DownloadVisualize
BU of 6de7 by Molmil
Crystal Structure at 4.3 A Resolution of Glycosylated HIV-1 Clade A BG505 SOSIP.664 Prefusion Env Trimer with Interdomain Stabilization 113C-429GCG in Complex with Broadly Neutralizing Antibodies PGT122 and 35O22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 heavy chain, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2018-05-11
Release date:2018-06-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.123 Å)
Cite:Interdomain Stabilization Impairs CD4 Binding and Improves Immunogenicity of the HIV-1 Envelope Trimer.
Cell Host Microbe, 23, 2018
7MFG
DownloadVisualize
BU of 7mfg by Molmil
Cryo-EM structure of the VRC310 clinical trial, vaccine-elicited, human antibody 310-030-1D06 Fab in complex with an H1 NC99 HA trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 310-030-1D06 Heavy, 310-030-1D06 Light, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2021-04-09
Release date:2021-11-03
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination.
Nat Med, 28, 2022
6TYB
DownloadVisualize
BU of 6tyb by Molmil
Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2019-08-08
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields.
Immunity, 51, 2019
7KC1
DownloadVisualize
BU of 7kc1 by Molmil
Cryo-EM structure of SRR2899884.46167H+MEDI8852L fab in complex with Victoria HA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2020-10-04
Release date:2021-05-12
Last modified:2021-07-14
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses.
Front Immunol, 12, 2021
7LZE
DownloadVisualize
BU of 7lze by Molmil
Cryo-EM Structure of disulfide stabilized HMPV F v4-B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
Authors:Gorman, J, Kwong, P.D.
Deposit date:2021-03-09
Release date:2021-08-25
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Interprotomer disulfide-stabilized variants of the human metapneumovirus fusion glycoprotein induce high titer-neutralizing responses.
Proc.Natl.Acad.Sci.USA, 118, 2021
7LQV
DownloadVisualize
BU of 7lqv by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody 4-8 Fab in complex with SARS-CoV-2 S2P spike
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-8 Heavy Chain, 4-8 Light chain, ...
Authors:Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L.
Deposit date:2021-02-15
Release date:2021-03-24
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Potent SARS-CoV-2 Neutralizing Antibodies Directed Against Spike N-Terminal Domain Target a Single Supersite
Cell Host Microbe, 2021
7LQW
DownloadVisualize
BU of 7lqw by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody 2-17 Fab in complex with SARS-CoV-2 S2P spike
Descriptor: 2-17 Heavy Chain, 2-17 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L.
Deposit date:2021-02-15
Release date:2021-03-24
Last modified:2021-05-26
Method:ELECTRON MICROSCOPY (4.47 Å)
Cite:Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cell Host Microbe, 29, 2021
6VRY
DownloadVisualize
BU of 6vry by Molmil
Structure of NCI09 fab in complex with SIV V2 peptide
Descriptor: NCI09 heavy chain, NCI09 light chain, SIV V2 peptide, ...
Authors:Gorman, J, Ahmadi, M, Kwong, P.D.
Deposit date:2020-02-10
Release date:2020-12-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:HIV vaccine candidate with V1 deletion reveals virus vulnerability to V2 antibodies
Iscience, 2020
7LY9
DownloadVisualize
BU of 7ly9 by Molmil
Cryo-EM structure of 2909 Fab in complex with 3BNC117 Fab and CAP256.wk34.c80 SOSIP.RnS2 N160K HIV-1 Env trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2909 Heavy Chain, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2021-03-06
Release date:2021-08-18
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces.
Nat Commun, 12, 2021
1YDG
DownloadVisualize
BU of 1ydg by Molmil
Crystal Structure of Trp repressor binding protein WrbA
Descriptor: SULFATE ION, trp repressor binding protein WrbA
Authors:Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2004-12-23
Release date:2005-01-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide.
Protein Sci., 14, 2005
7LPN
DownloadVisualize
BU of 7lpn by Molmil
Cryo-EM structure of llama J3 VHH antibody in complex with HIV-1 Env BG505 DS-SOSIP.664
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2021-02-12
Release date:2022-02-23
Last modified:2023-03-29
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.
Structure, 30, 2022
2A1F
DownloadVisualize
BU of 2a1f by Molmil
Crystal Structure of Uridylate kinase
Descriptor: Uridylate kinase
Authors:Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-06-20
Release date:2005-06-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Uridylate kinase
To be Published
1YRH
DownloadVisualize
BU of 1yrh by Molmil
Crystal Structure Of Trp Repressor Binding Protein Wrba in complex with FMN
Descriptor: FLAVIN MONONUCLEOTIDE, trp repressor binding protein WrbA
Authors:Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-02-03
Release date:2005-02-15
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Crystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide.
Protein Sci., 14, 2005
2AKO
DownloadVisualize
BU of 2ako by Molmil
Crystal structure of Glutamate 5-kinase from Campylobacter jejuni
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glutamate 5-kinase
Authors:Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-08-03
Release date:2005-08-09
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Glutamate 5-kinase from Campylobacter jejuni
To be Published
2AWD
DownloadVisualize
BU of 2awd by Molmil
Crystal structure of LacC from Enterococcus faecalis
Descriptor: BROMIDE ION, tagatose-6-phosphate kinase
Authors:Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-08-31
Release date:2005-09-13
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of LacC from Enterococcus faecalis
To be Published
1Y65
DownloadVisualize
BU of 1y65 by Molmil
Crystal structure of beta-hexosaminidase from Vibrio cholerae in complex with N-acetyl-D-glucosamine to a resolution of 1.85
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-hexosaminidase
Authors:Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2004-12-03
Release date:2004-12-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of beta-hexosaminidase from Vibrio cholerae in complex with N-acetyl-D-glucosamine to a resolution of 1.85
To be Published
7KJP
DownloadVisualize
BU of 7kjp by Molmil
Disulfide Stabilized Norovirus GI.1 VLP Shell Region
Descriptor: Capsid protein VP1
Authors:Gorman, J, Kwong, P.D.
Deposit date:2020-10-26
Release date:2020-12-02
Last modified:2020-12-30
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Disulfide stabilization of human norovirus GI.1 virus-like particles focuses immune response toward blockade epitopes.
NPJ Vaccines, 5, 2020
1TO3
DownloadVisualize
BU of 1to3 by Molmil
Structure of yiht from Salmonella typhimurium
Descriptor: BROMIDE ION, PHOSPHATE ION, Putative aldolase yihT
Authors:Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2004-06-11
Release date:2004-06-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of yiht from Salmonella typhimurium
To be Published
1S80
DownloadVisualize
BU of 1s80 by Molmil
Structure of Serine Acetyltransferase from Haemophilis influenzae Rd
Descriptor: Serine acetyltransferase
Authors:Gorman, J, Gogos, A, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2004-01-30
Release date:2004-08-31
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of serine acetyltransferase from Haemophilus influenzae Rd.
Acta Crystallogr.,Sect.D, 60, 2004

224201

数据于2024-08-28公开中

PDB statisticsPDBj update infoContact PDBjnumon