8Y16
 
 | | Cryo-EM structure of SARS-CoV-2 Omicron JN.1 spike protein in complex with human ACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | Authors: | Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F. | | Deposit date: | 2024-01-23 | | Release date: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Spike structures, receptor binding and immune escape of SARS-CoV-2 Omicron recently-circulating BA.2.86.1, JN.1, EG.5, EG.5.1 and HV.1 sub-variants
To Be Published
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6IEK
 | | Structure of RVFV Gn and human monoclonal antibody R12 | | Descriptor: | Heavy chain of Fab R12, Light chain of Fab R12, NSmGnGc | | Authors: | Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F. | | Deposit date: | 2018-09-14 | | Release date: | 2019-04-10 | | Last modified: | 2019-07-10 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
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8GPU
 | | YFV_E_YD6Fab_prefusion | | Descriptor: | Envelope protein, YD6Fab_H, YD6Fab_L | | Authors: | Li, Y, Wu, L, Qi, J, Yan, J, Gao, G.F. | | Deposit date: | 2022-08-27 | | Release date: | 2022-11-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus.
Innovation (N Y), 3, 2022
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6IEA
 | | Structure of RVFV Gn and human monoclonal antibody R13 | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, NSmGnGc, ... | | Authors: | Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F. | | Deposit date: | 2018-09-13 | | Release date: | 2019-04-10 | | Last modified: | 2019-07-10 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
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5XOT
 | | Crystal structure of pHLA-B35 in complex with TU55 T cell receptor | | Descriptor: | An HIV reverse transcriptase epitope, Beta-2-microglobulin, GLYCEROL, ... | | Authors: | Shi, Y, Qi, J, Gao, G.F. | | Deposit date: | 2017-05-31 | | Release date: | 2017-06-14 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.787 Å) | | Cite: | Conserved V delta 1 Binding Geometry in a Setting of Locus-Disparate pHLA Recognition by delta / alpha beta T Cell Receptors (TCRs): Insight into Recognition of HIV Peptides by TCRs.
J. Virol., 91, 2017
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6IEB
 | | Structure of RVFV Gn and human monoclonal antibody R15 | | Descriptor: | NSmGnGc, R15 H chain, R15 L chain | | Authors: | Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F. | | Deposit date: | 2018-09-13 | | Release date: | 2019-04-10 | | Last modified: | 2019-07-10 | | Method: | X-RAY DIFFRACTION (2.409 Å) | | Cite: | Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
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4F7T
 | | Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009 H1N1 PB1 (498-505) | | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... | | Authors: | Liu, J, Zhang, S, Tan, S, Yi, Y, Wu, B, Zhu, F, Wang, H, Qi, J, Gao, G.F. | | Deposit date: | 2012-05-16 | | Release date: | 2012-10-10 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals.
J.Virol., 86, 2012
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5GZN
 | | Structure of neutralizing antibody bound to Zika envelope protein | | Descriptor: | Antibody Heavy chain, Antibody light chain, Genome polyprotein | | Authors: | Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F. | | Deposit date: | 2016-09-29 | | Release date: | 2016-12-28 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
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6IEC
 | | Structure of RVFV Gn and human monoclonal antibody R17 | | Descriptor: | NSmGnGc, R17 H chain, R17 L chain | | Authors: | Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F. | | Deposit date: | 2018-09-13 | | Release date: | 2019-04-10 | | Last modified: | 2019-07-10 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
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4LL9
 | | Crystal structure of D3D4 domain of the LILRB1 molecule | | Descriptor: | IODIDE ION, Leukocyte immunoglobulin-like receptor subfamily B member 1 | | Authors: | Nam, G, Shi, Y, Ryu, M, Wang, Q, Song, H, Liu, J, Yan, J, Qi, J, Gao, G.F. | | Deposit date: | 2013-07-09 | | Release date: | 2013-09-11 | | Last modified: | 2013-11-06 | | Method: | X-RAY DIFFRACTION (2.686 Å) | | Cite: | Crystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA binding
Protein Cell, 4, 2013
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5GZO
 | | Structure of neutralizing antibody bound to Zika envelope protein | | Descriptor: | Antibody heavy chain, Antibody light chain, Genome polyprotein | | Authors: | Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F. | | Deposit date: | 2016-09-29 | | Release date: | 2017-01-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.755 Å) | | Cite: | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
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4NFZ
 | | Crystal structure of polymerase subunit PA N-terminal endonuclease domain from bat-derived influenza virus H17N10 | | Descriptor: | MANGANESE (II) ION, Polymerase PA | | Authors: | Tefsen, B, Lu, G, Zhu, Y, Haywood, J, Zhao, L, Deng, T, Qi, J, Gao, G.F. | | Deposit date: | 2013-11-01 | | Release date: | 2013-12-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The N-Terminal Domain of PA from Bat-Derived Influenza-Like Virus H17N10 Has Endonuclease Activity
J.Virol., 88, 2014
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7C9V
 | | E30 F-particle in complex with FcRn | | Descriptor: | Beta-2-microglobulin, IgG receptor FcRn large subunit p51, MYRISTIC ACID, ... | | Authors: | Wang, K, Zhu, L, Sun, Y, Li, M, Zhao, X, Cui, L, Zhang, L, Gao, G, Zhai, W, Zhu, F, Rao, Z, Wang, X. | | Deposit date: | 2020-06-07 | | Release date: | 2020-07-29 | | Last modified: | 2020-09-16 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage.
Nat Commun, 11, 2020
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7C9W
 | | E30 F-particle in complex with CD55 | | Descriptor: | Complement decay-accelerating factor, MYRISTIC ACID, SPHINGOSINE, ... | | Authors: | Wang, K, Zhu, L, Sun, Y, Li, M, Zhao, X, Cui, L, Zhang, L, Gao, G, Zhai, W, Zhu, F, Rao, Z, Wang, X. | | Deposit date: | 2020-06-07 | | Release date: | 2020-07-29 | | Last modified: | 2020-09-16 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage.
Nat Commun, 11, 2020
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3U82
 | | Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion | | Descriptor: | Envelope glycoprotein D, Poliovirus receptor-related protein 1 | | Authors: | Zhang, N, Yan, J, Lu, G, Guo, Z, Fan, Z, Wang, J, Shi, Y, Qi, J, Gao, G.F. | | Deposit date: | 2011-10-15 | | Release date: | 2012-03-21 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.164 Å) | | Cite: | Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion.
Nat Commun, 2, 2011
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4MYW
 | | Structure of HSV-2 gD bound to nectin-1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D, ... | | Authors: | Lu, G, Zhang, N, Qi, J, Li, Y, Chen, Z, Zheng, C, Yan, J, Gao, G.F. | | Deposit date: | 2013-09-28 | | Release date: | 2014-10-01 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.189 Å) | | Cite: | Crystal structure of herpes simplex virus 2 gD bound to nectin-1 reveals a conserved mode of receptor recognition.
J.Virol., 88, 2014
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6A3V
 | | Complex structure of human 4-1BB and 4-1BBL | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9 | | Authors: | Li, Y, Zhang, C, Chai, Y, Qi, J, Tien, P, Gao, S, Gao, G.F. | | Deposit date: | 2018-06-17 | | Release date: | 2018-10-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.391 Å) | | Cite: | Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab.
Cell Rep, 25, 2018
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3U83
 | | Crystal structure of nectin-1 | | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, Poliovirus receptor-related protein 1 | | Authors: | Zhang, N, Yan, J, Lu, G, Guo, Z, Fan, Z, Wang, J, Shi, Y, Qi, J, Gao, G.F. | | Deposit date: | 2011-10-15 | | Release date: | 2012-03-21 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.499 Å) | | Cite: | Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion.
Nat Commun, 2, 2011
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6A3W
 | | Complex structure of 4-1BB and utomilumab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor receptor superfamily member 9, utomilumab VH, ... | | Authors: | Li, Y, Tan, S, Zhang, C, Chai, Y, Qi, J, Tien, P, Gao, S, Gao, G.F. | | Deposit date: | 2018-06-17 | | Release date: | 2018-10-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab.
Cell Rep, 25, 2018
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4LLA
 | | Crystal structure of D3D4 domain of the LILRB2 molecule | | Descriptor: | Leukocyte immunoglobulin-like receptor subfamily B member 2 | | Authors: | Nam, G, Shi, Y, Ryu, M, Wang, Q, Song, H, Liu, J, Yan, J, Qi, J, Gao, G.F. | | Deposit date: | 2013-07-09 | | Release date: | 2013-09-11 | | Last modified: | 2013-11-06 | | Method: | X-RAY DIFFRACTION (2.502 Å) | | Cite: | Crystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA binding
Protein Cell, 4, 2013
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4NFD
 | | Structure of PILR L108W mutant in complex with sialic acid | | Descriptor: | N-acetyl-alpha-neuraminic acid, Paired immunoglobulin-like type 2 receptor beta | | Authors: | Lu, Q, Lu, G, Qi, J, Li, Y, Zhang, Y, Wang, H, Fan, Z, Yan, J, Gao, G.F. | | Deposit date: | 2013-10-31 | | Release date: | 2014-05-28 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.708 Å) | | Cite: | PILR alpha and PILR beta have a siglec fold and provide the basis of binding to sialic acid
Proc.Natl.Acad.Sci.USA, 111, 2014
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4NFC
 | | Structure of paired immunoglobulin-like type 2 receptor (PILR ) | | Descriptor: | Paired immunoglobulin-like type 2 receptor beta | | Authors: | Lu, Q, Lu, G, Qi, J, Li, Y, Zhang, Y, Wang, H, Fan, Z, Yan, J, Gao, G.F. | | Deposit date: | 2013-10-31 | | Release date: | 2014-05-28 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | PILR alpha and PILR beta have a siglec fold and provide the basis of binding to sialic acid
Proc.Natl.Acad.Sci.USA, 111, 2014
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4MYV
 | | Free HSV-2 gD structure | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D | | Authors: | Lu, G, Zhang, N, Qi, J, Li, Y, Chen, Z, Zheng, C, Yan, J, Gao, G.F. | | Deposit date: | 2013-09-28 | | Release date: | 2014-10-01 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.801 Å) | | Cite: | Crystal structure of herpes simplex virus 2 gD bound to nectin-1 reveals a conserved mode of receptor recognition.
J.Virol., 88, 2014
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3QZW
 | | Plasticity of human CD8 binding to peptide-HLA-A*2402 | | Descriptor: | 10-mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Shi, Y, Qi, J, Gao, G.F. | | Deposit date: | 2011-03-07 | | Release date: | 2011-06-29 | | Last modified: | 2013-07-03 | | Method: | X-RAY DIFFRACTION (2.798 Å) | | Cite: | Plasticity of human CD8alpha alpha binding to peptide-HLA-A*2402
Mol.Immunol., 48, 2011
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4KPS
 | | Structure and receptor binding specificity of the hemagglutinin H13 from avian influenza A virus H13N6 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, ... | | Authors: | Lu, X, Qi, J, Shi, Y, Gao, G. | | Deposit date: | 2013-05-14 | | Release date: | 2013-07-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.587 Å) | | Cite: | Structure and Receptor Binding Specificity of Hemagglutinin H13 from Avian Influenza A Virus H13N6
J.Virol., 87, 2013
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