7XQS
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![BU of 7xqs by Molmil](/molmil-images/mine/7xqs) | The structure of FLA-K*00701/KP-CoV-9 | Descriptor: | Beta-2-microglobulin, MHC class I antigen alpha chain, peptide from Spike glycoprotein | Authors: | Qiao, P.W, Yue, C, Peng, W.Y, Liu, K.F, Huo, S.T, Zhang, D, Chai, Y, Qi, J.X, Sun, Z.Y, Gao, G.F, Liu, W.J, Wu, G.Z. | Deposit date: | 2022-05-08 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Analysis of the characteristics of feline major histocompatibility complex class I molecules cross-presenting coronavirus peptides To Be Published
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6M24
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![BU of 6m24 by Molmil](/molmil-images/mine/6m24) | Uncommon structural features of rabbit MHC class I (RLA-A1) complexed with rabbit haemorrhagic disease virus (RHDV) derived peptide, VP60-2 | Descriptor: | Beta-2-microglobulin, RLA class I histocompatibility antigen, alpha chain 19-1, ... | Authors: | Zhang, Q.X, Liu, K.F, Yue, C, Zhang, D, Lu, D, Xiao, W.L, Liu, P.P, Zhao, Y.Z, Gao, G.L, Ding, C.M, Lyu, J.X, Liu, W.J. | Deposit date: | 2020-02-26 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Strict Assembly Restriction of Peptides from Rabbit Hemorrhagic Disease Virus Presented by Rabbit Major Histocompatibility Complex Class I Molecule RLA-A1. J.Virol., 94, 2020
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6M2J
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![BU of 6m2j by Molmil](/molmil-images/mine/6m2j) | Uncommon structural features of rabbit MHC class I (RLA-A1) complexed with rabbit haemorrhagic disease virus (RHDV) derived peptide, VP60-1 | Descriptor: | Beta-2-microglobulin, RLA class I histocompatibility antigen, alpha chain 19-1, ... | Authors: | Zhang, Q.X, Liu, K.F, Yue, C, Zhang, D, Lu, D, Xiao, W.L, Liu, P.P, Zhao, Y.Z, Gao, G.L, Ding, C.M, Lyu, J.X, Liu, W.J. | Deposit date: | 2020-02-27 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Strict Assembly Restriction of Peptides from Rabbit Hemorrhagic Disease Virus Presented by Rabbit Major Histocompatibility Complex Class I Molecule RLA-A1. J.Virol., 94, 2020
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6M2K
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![BU of 6m2k by Molmil](/molmil-images/mine/6m2k) | Uncommon structural features of rabbit MHC class I (RLA-A1) complexed with rabbit haemorrhagic disease virus (RHDV) derived peptide, VP60-10 | Descriptor: | Beta-2-microglobulin, RLA class I histocompatibility antigen, alpha chain 19-1, ... | Authors: | Zhang, Q.X, Liu, K.F, Yue, C, Zhang, D, Lu, D, Xiao, W.L, Liu, P.P, Zhao, Y.Z, Gao, G.L, Ding, C.M, Lyu, J.X, Liu, W.J. | Deposit date: | 2020-02-27 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Strict Assembly Restriction of Peptides from Rabbit Hemorrhagic Disease Virus Presented by Rabbit Major Histocompatibility Complex Class I Molecule RLA-A1. J.Virol., 94, 2020
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7W8S
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![BU of 7w8s by Molmil](/molmil-images/mine/7w8s) | Structure of SARS-CoV-2 spike receptor-binding domain Y453F mutation complexed with American mink ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ... | Authors: | Su, C, Qi, J.X, Gao, G.F. | Deposit date: | 2021-12-08 | Release date: | 2022-08-17 | Last modified: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Molecular Basis of Mink ACE2 Binding to SARS-CoV-2 and Its Mink-Derived Variants. J.Virol., 96, 2022
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7WA1
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![BU of 7wa1 by Molmil](/molmil-images/mine/7wa1) | |
7CP2
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![BU of 7cp2 by Molmil](/molmil-images/mine/7cp2) | Crystal structure of the African swine fever virus core shell protein p15 | Descriptor: | CP530R | Authors: | Liu, K.F, Meng, Y.M, Chai, Y, Li, L.J, Sun, H, Gao, G.F, Tan, S.G, Qi, J.X. | Deposit date: | 2020-08-05 | Release date: | 2020-10-28 | Last modified: | 2021-05-19 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Crystal structure of the African swine fever virus core shell protein p15 Biosaf Health, 2021
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7CU5
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![BU of 7cu5 by Molmil](/molmil-images/mine/7cu5) | N-Glycosylation of PD-1 and glycosylation dependent binding of PD-1 specific monoclonal antibody camrelizumab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Programmed cell death protein 1, ... | Authors: | Liu, K.F, Tan, S.G, Jin, W.J, Guan, J.W, Wang, W.L, Sun, H, Qi, J.X, Yan, J.H, Chai, Y, Wang, Z.F, Chu, X.D, Gao, G.F. | Deposit date: | 2020-08-21 | Release date: | 2020-10-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | N-glycosylation of PD-1 promotes binding of camrelizumab. Embo Rep., 21, 2020
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7XNF
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![BU of 7xnf by Molmil](/molmil-images/mine/7xnf) | Structure of SARS-CoV-2 antibody P2C-1F11 with GX/P2V/2017 RBD | Descriptor: | P2C-1F11 Heavy Chain, P2C-1F11 Lambda chain, Spike protein S1 | Authors: | Jia, Y.F, Chai, Y, Wang, Q.H, Gao, G.F. | Deposit date: | 2022-04-28 | Release date: | 2023-01-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Cross-reaction of current available SARS-CoV-2 MAbs against the pangolin-origin coronavirus GX/P2V/2017. Cell Rep, 41, 2022
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7DRV
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![BU of 7drv by Molmil](/molmil-images/mine/7drv) | Structural basis of SARS-CoV-2-closely-related bat coronavirus RaTG13 to hACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Liu, K.F, Pan, X.Q, Li, L.J, Feng, Y, Meng, Y.M, Zhang, Y.F, Wu, L.L, Chen, Q, Zheng, A.Q, Song, C.L, Jia, Y.F, Niu, S, Qiao, C.P, Zhao, X, Ma, D.L, Ma, X.P, Tan, S.G, Qi, J.X, Gao, G.F, Wang, Q.H. | Deposit date: | 2020-12-29 | Release date: | 2021-08-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Binding and molecular basis of the bat coronavirus RaTG13 virus to ACE2 in humans and other species. Cell, 184, 2021
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7CZE
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![BU of 7cze by Molmil](/molmil-images/mine/7cze) | Crystal structure of Epstein-Barr virus (EBV) gHgL and in complex with the ligand binding domian (LBD) of EphA2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ... | Authors: | Su, C, Wu, L.L, Song, H, Chai, Y, Qi, J.X, Yan, J.H, Gao, G.F. | Deposit date: | 2020-09-08 | Release date: | 2020-10-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Molecular basis of EphA2 recognition by gHgL from gammaherpesviruses. Nat Commun, 11, 2020
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7XYQ
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![BU of 7xyq by Molmil](/molmil-images/mine/7xyq) | Crystal strucutre of PD-L1 and the computationally designed DBL1_03 protein binder | Descriptor: | ARGININE, CD274 molecule, DBL1_03 | Authors: | Liu, K, Xu, Z, Han, P, Pacesa, M, Gao, G.F, Chai, Y, Tan, S. | Deposit date: | 2022-06-02 | Release date: | 2023-04-12 | Last modified: | 2023-05-17 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | De novo design of protein interactions with learned surface fingerprints. Nature, 617, 2023
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6KLH
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![BU of 6klh by Molmil](/molmil-images/mine/6klh) | Dimeric structure of Machupo virus polymerase bound to vRNA promoter | Descriptor: | MANGANESE (II) ION, RNA (5'-R(*GP*CP*CP*UP*AP*GP*GP*AP*UP*CP*CP*AP*CP*UP*GP*UP*GP*CP*G)-3'), RNA-directed RNA polymerase L, ... | Authors: | Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. | Deposit date: | 2019-07-30 | Release date: | 2020-03-18 | Last modified: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insight into arenavirus replication machinery. Nature, 579, 2020
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7C02
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![BU of 7c02 by Molmil](/molmil-images/mine/7c02) | Crystal structure of dimeric MERS-CoV receptor binding domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Dai, L, Qi, J, Gao, G.F. | Deposit date: | 2020-04-30 | Release date: | 2020-07-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS. Cell, 182, 2020
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7BZU
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![BU of 7bzu by Molmil](/molmil-images/mine/7bzu) | Cryo-EM structure of mature Coxsackievirus A10 in complex with KRM1 at pH 5.5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein VP1, Capsid protein VP2, ... | Authors: | Cui, Y, Peng, R, Song, H, Tong, Z, Gao, G.F, Qi, J. | Deposit date: | 2020-04-28 | Release date: | 2020-07-22 | Last modified: | 2020-08-19 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1. Proc.Natl.Acad.Sci.USA, 117, 2020
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7C8J
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![BU of 7c8j by Molmil](/molmil-images/mine/7c8j) | Structural basis for cross-species recognition of COVID-19 virus spike receptor binding domain to bat ACE2 | Descriptor: | Angiotensin-converting enzyme, SARS-CoV-2 Receptor binding domain, ZINC ION | Authors: | Liu, K.F, Wang, J, Tan, S.G, Niu, S, Wu, L.L, Zhang, Y.F, Pan, X.Q, Meng, Y.M, Chen, Q, Wang, Q.H, Wang, H.W, Qi, J.X, Gao, G.F. | Deposit date: | 2020-06-01 | Release date: | 2021-01-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.18 Å) | Cite: | Cross-species recognition of SARS-CoV-2 to bat ACE2. Proc.Natl.Acad.Sci.USA, 118, 2021
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7CDZ
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![BU of 7cdz by Molmil](/molmil-images/mine/7cdz) | |
7C8K
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![BU of 7c8k by Molmil](/molmil-images/mine/7c8k) | Structural basis for cross-species recognition of COVID-19 virus spike receptor binding domain to bat ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | Authors: | Liu, K.F, Wang, J, Tan, S.G, Niu, S, Wu, L.L, Zhang, Y.F, Pan, X.Q, Meng, Y.M, Chen, Q, Wang, Q.H, Wang, H.W, Qi, J.X, Gao, G.F. | Deposit date: | 2020-06-02 | Release date: | 2021-01-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cross-species recognition of SARS-CoV-2 to bat ACE2. Proc.Natl.Acad.Sci.USA, 118, 2021
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7CE0
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![BU of 7ce0 by Molmil](/molmil-images/mine/7ce0) | |
7WVM
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![BU of 7wvm by Molmil](/molmil-images/mine/7wvm) | The complex structure of PD-1 and cemiplimab | Descriptor: | Heavy Chain of Cemiplimab, Light Chain of Cemiplimab, Programmed cell death protein 1 | Authors: | Lu, D, Xu, Z.P, Liu, K.F, Tan, S.G, Gao, G.F, Chai, Y. | Deposit date: | 2022-02-10 | Release date: | 2022-04-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | PD-1 N58-Glycosylation-Dependent Binding of Monoclonal Antibody Cemiplimab for Immune Checkpoint Therapy. Front Immunol, 13, 2022
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7D1M
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![BU of 7d1m by Molmil](/molmil-images/mine/7d1m) | CRYSTAL STRUCTURE OF THE SARS-CoV-2 MAIN PROTEASE COMPLEXED WITH GC376 | Descriptor: | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, DIMETHYL SULFOXIDE | Authors: | Fu, L.F, Gilski, M, Shabalin, I, Gao, G.F, Qi, J.X. | Deposit date: | 2020-09-14 | Release date: | 2020-10-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease. Nat Commun, 11, 2020
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7DEB
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![BU of 7deb by Molmil](/molmil-images/mine/7deb) | Structure of an avian influenza H5 hemagglutinin from the influenza virus A/duck/Eastern China/L0230/2010 (H5N2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | Authors: | Sun, H, Sun, H, Song, J, Zhang, W, Qi, J, Gao, G.F, Liu, J. | Deposit date: | 2020-11-03 | Release date: | 2021-11-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Haemagglutinin and neuraminidase acid stability in H5N6 avian influenza virus confers infection adaptation in mammals To Be Published
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7DDP
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![BU of 7ddp by Molmil](/molmil-images/mine/7ddp) | Cryo-EM structure of human ACE2 and GX/P2V/2017 RBD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ... | Authors: | Niu, S, Wang, J, Wang, H.W, Qi, J.X, Wang, Q.H, Gao, G.F. | Deposit date: | 2020-10-29 | Release date: | 2021-05-19 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Molecular basis of cross-species ACE2 interactions with SARS-CoV-2-like viruses of pangolin origin. Embo J., 40, 2021
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7DDO
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![BU of 7ddo by Molmil](/molmil-images/mine/7ddo) | Cryo-EM structure of human ACE2 and GD/1/2019 RBD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ... | Authors: | Niu, S, Wang, J, Wang, H.W, Qi, J.X, Wang, Q.H, Gao, G.F. | Deposit date: | 2020-10-29 | Release date: | 2021-05-19 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Molecular basis of cross-species ACE2 interactions with SARS-CoV-2-like viruses of pangolin origin. Embo J., 40, 2021
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7EIN
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![BU of 7ein by Molmil](/molmil-images/mine/7ein) | SARS-CoV-2 main proteinase complex with microbial metabolite leupeptin | Descriptor: | 3C-like proteinase, leupeptin | Authors: | Fu, L.F, Feng, Y, Qi, J.X, Gao, G.F. | Deposit date: | 2021-03-31 | Release date: | 2021-07-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Mechanism of Microbial Metabolite Leupeptin in the Treatment of COVID-19 by Traditional Chinese Medicine Herbs. Mbio, 12, 2021
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