7EIN

SARS-CoV-2 main proteinase complex with microbial metabolite leupeptin

Summary for 7EIN

• Entry DOI: 10.2210/pdb7ein/pdb
• Descriptor: 3C-like proteinase, leupeptin (3 entities in total)
• Functional Keywords: sars-cov-2, main proteinase, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 4
• Total formula weight: 68508.23

Authors

Fu, L.F.,Feng, Y.,Qi, J.X.,Gao, G.F. (deposition date: 2021-03-31, release date: 2021-07-07, Last modification date: 2023-11-29)

• Primary citation: Fu, L.,Shao, S.,Feng, Y.,Ye, F.,Sun, X.,Wang, Q.,Yu, F.,Wang, Q.,Huang, B.,Niu, P.,Li, X.,Wong, C.C.L.,Qi, J.,Tan, W.,Gao, G.F.; Mechanism of Microbial Metabolite Leupeptin in the Treatment of COVID-19 by Traditional Chinese Medicine Herbs.; Mbio, 12:e0222021-e0222021, 2021; PubMed: 34579576; DOI: 10.1128/mBio.02220-21

Experimental method

X-RAY DIFFRACTION (1.7 Å)