3MN5
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![BU of 3mn5 by Molmil](/molmil-images/mine/3mn5) | Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Ducka, A.M, Sitar, T, Popowicz, G.M, Huber, R, Holak, T.A. | Deposit date: | 2010-04-21 | Release date: | 2010-06-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation. Proc.Natl.Acad.Sci.USA, 107, 2010
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3HOR
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![BU of 3hor by Molmil](/molmil-images/mine/3hor) | Structure of the actin-binding domain of human filamin A (reduced) | Descriptor: | Filamin-A, PHOSPHATE ION | Authors: | Clark, A.R, Sawyer, G.M, Robertson, S.P, Sutherland-Smith, A.J. | Deposit date: | 2009-06-03 | Release date: | 2009-10-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders Hum.Mol.Genet., 18, 2009
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3LVZ
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![BU of 3lvz by Molmil](/molmil-images/mine/3lvz) | New refinement of the crystal structure of BJP-1, a subclass B3 metallo-beta-lactamase of Bradyrhizobium japonicum | Descriptor: | Blr6230 protein, ZINC ION | Authors: | Docquier, J.D, Benvenuti, M, Calderone, V, Stoczko, M, Rossolini, G.M, Mangani, S. | Deposit date: | 2010-02-23 | Release date: | 2011-01-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | High-resolution crystal structure of the subclass B3 metallo-beta-lactamase BJP-1: rational basis for substrate specificity and interaction with sulfonamides. Antimicrob.Agents Chemother., 54, 2010
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3HOC
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![BU of 3hoc by Molmil](/molmil-images/mine/3hoc) | Structure of the actin-binding domain of human filamin A mutant E254K | Descriptor: | Filamin-A, PHOSPHATE ION | Authors: | Clark, A.R, Sawyer, G.M, Robertson, S.P, Sutherland-Smith, A.J. | Deposit date: | 2009-06-02 | Release date: | 2009-10-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders Hum.Mol.Genet., 18, 2009
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2O3D
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![BU of 2o3d by Molmil](/molmil-images/mine/2o3d) | Structure of human SF2/ASF RNA recognition motif 2 (RRM2) | Descriptor: | Splicing factor, arginine/serine-rich 1 | Authors: | Tintaru, A.M, Hautbergue, G.M, Hounslow, A.M, Lian, L.Y, Craven, C.J, Wilson, S.A. | Deposit date: | 2006-12-01 | Release date: | 2007-10-16 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structural and functional analysis of RNA and TAP binding to SF2/ASF. Embo Rep., 8, 2007
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8DYT
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![BU of 8dyt by Molmil](/molmil-images/mine/8dyt) | Cryo-EM structure of 227 Fab in complex with (NPNA)8 peptide | Descriptor: | 227 Fab heavy chain, 227 Fab light chain, Circumsporozoite protein | Authors: | Martin, G.M, Ward, A.B. | Deposit date: | 2022-08-05 | Release date: | 2023-08-02 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection. Nat Commun, 14, 2023
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3IZ0
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![BU of 3iz0 by Molmil](/molmil-images/mine/3iz0) | Human Ndc80 Bonsai Decorated Microtubule | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Alushin, G.M, Ramey, V.H, Pasqualato, S, Ball, D.A, Grigorieff, N, Musacchio, A, Nogales, E. | Deposit date: | 2010-08-09 | Release date: | 2010-10-13 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (8.6 Å) | Cite: | The Ndc80 kinetochore complex forms oligomeric arrays along microtubules. Nature, 467, 2010
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8DYW
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![BU of 8dyw by Molmil](/molmil-images/mine/8dyw) | |
8DYY
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![BU of 8dyy by Molmil](/molmil-images/mine/8dyy) | |
8DZ3
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![BU of 8dz3 by Molmil](/molmil-images/mine/8dz3) | |
8DZ5
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![BU of 8dz5 by Molmil](/molmil-images/mine/8dz5) | |
8DYX
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![BU of 8dyx by Molmil](/molmil-images/mine/8dyx) | |
8DZ4
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![BU of 8dz4 by Molmil](/molmil-images/mine/8dz4) | |
3P98
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![BU of 3p98 by Molmil](/molmil-images/mine/3p98) | The crystal structure of the extended spectrum beta-lactamase TEM-72 reveals inhibition by citrate | Descriptor: | Beta-lactamase TEM-72, CITRIC ACID, DI(HYDROXYETHYL)ETHER | Authors: | Docquier, J.D, Benvenuti, M, Calderone, V, Rossolini, G.M, Mangani, S. | Deposit date: | 2010-10-16 | Release date: | 2011-03-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the extended-spectrum [beta]-lactamase TEM-72 inhibited by citrate Acta Crystallogr.,Sect.F, 67, 2011
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8EH5
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![BU of 8eh5 by Molmil](/molmil-images/mine/8eh5) | Cryo-EM structure of L9 Fab in complex with rsCSP | Descriptor: | Circumsporozoite protein, L9 Heavy chain, L9 Light chain | Authors: | Martin, G.M, Ward, A.B. | Deposit date: | 2022-09-13 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9. Nat Commun, 14, 2023
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3MBS
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![BU of 3mbs by Molmil](/molmil-images/mine/3mbs) | Crystal structure of 8mer PNA | Descriptor: | 1,2-ETHANEDIOL, Peptide Nucleic Acid | Authors: | Yeh, J.I, Pohl, E, Truan, D, He, W, Sheldrick, G.M, Achim, C. | Deposit date: | 2010-03-26 | Release date: | 2011-03-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | The crystal structure of non-modified and bipyridine-modified PNA duplexes. Chemistry, 16, 2010
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3MN6
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![BU of 3mn6 by Molmil](/molmil-images/mine/3mn6) | Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ... | Authors: | Ducka, A.M, Sitar, T, Popowicz, G.M, Huber, R, Holak, T.A. | Deposit date: | 2010-04-21 | Release date: | 2010-06-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation. Proc.Natl.Acad.Sci.USA, 107, 2010
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3MDG
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![BU of 3mdg by Molmil](/molmil-images/mine/3mdg) | |
3MN9
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![BU of 3mn9 by Molmil](/molmil-images/mine/3mn9) | Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ... | Authors: | Ducka, A.M, Sitar, T, Popowicz, G.M, Huber, R, Holak, T.A. | Deposit date: | 2010-04-21 | Release date: | 2010-05-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation. Proc.Natl.Acad.Sci.USA, 107, 2010
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3MDI
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3MN7
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![BU of 3mn7 by Molmil](/molmil-images/mine/3mn7) | Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ... | Authors: | Ducka, A.M, Sitar, T, Popowicz, G.M, Huber, R, Holak, T.A. | Deposit date: | 2010-04-21 | Release date: | 2010-05-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation. Proc.Natl.Acad.Sci.USA, 107, 2010
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3LBL
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![BU of 3lbl by Molmil](/molmil-images/mine/3lbl) | Structure of human MDM2 protein in complex with Mi-63-analog | Descriptor: | (2'R,3R,4'R,5'R)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-N-(2-morpholin-4-ylethyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide, E3 ubiquitin-protein ligase Mdm2 | Authors: | Popowicz, G.M, Czarna, A, Wolf, S, Holak, T.A. | Deposit date: | 2010-01-08 | Release date: | 2010-03-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery Cell Cycle, 9, 2010
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2QS4
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![BU of 2qs4 by Molmil](/molmil-images/mine/2qs4) | Crystal structure of the GluR5 ligand binding core dimer in complex with LY466195 at 1.58 Angstroms resolution | Descriptor: | (3S,4aR,6S,8aR)-6-{[(2S)-2-carboxy-4,4-difluoropyrrolidin-1-yl]methyl}decahydroisoquinoline-3-carboxylic acid, AMMONIUM ION, GLYCEROL, ... | Authors: | Alushin, G.M, Jane, D.E, Mayer, M.L. | Deposit date: | 2007-07-30 | Release date: | 2008-08-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Binding site and ligand flexibility revealed by high resolution crystal structures of GluK1 competitive antagonists. Neuropharmacology, 60, 2011
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3LBK
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![BU of 3lbk by Molmil](/molmil-images/mine/3lbk) | Structure of human MDM2 protein in complex with a small molecule inhibitor | Descriptor: | 6-chloro-3-[1-(4-chlorobenzyl)-4-phenyl-1H-imidazol-5-yl]-1H-indole-2-carboxylic acid, E3 ubiquitin-protein ligase Mdm2, SULFATE ION | Authors: | Popowicz, G.M, Czarna, A, Wolf, S, Holak, T.A. | Deposit date: | 2010-01-08 | Release date: | 2010-03-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery Cell Cycle, 9, 2010
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3Q2S
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![BU of 3q2s by Molmil](/molmil-images/mine/3q2s) | Crystal Structure of CFIm68 RRM/CFIm25 complex | Descriptor: | Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6 | Authors: | Yang, Q, Coseno, M, Gilmartin, G.M, Doublie, S. | Deposit date: | 2010-12-20 | Release date: | 2011-02-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structure of a Human Cleavage Factor CFI(m)25/CFI(m)68/RNA Complex Provides an Insight into Poly(A) Site Recognition and RNA Looping. Structure, 19, 2011
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