3MN6

Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation

Summary for 3MN6

• Entry DOI: 10.2210/pdb3mn6/pdb
• Related: 2HF4 3MMV 3MN5 3MN7 3MN9
• Descriptor: Actin-5C, Protein spire, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: wh2 domain, spire, actin complex, contractile protein-protein binding complex, contractile protein/protein binding
• Biological source: Drosophila melanogaster (Fruit fly); More
• Cellular location: Cytoplasm, cytoskeleton: P10987 Q9U1K1
• Total number of polymer chains: 6
• Total formula weight: 131717.38

Authors

Ducka, A.M.,Sitar, T.,Popowicz, G.M.,Huber, R.,Holak, T.A. (deposition date: 2010-04-21, release date: 2010-06-02, Last modification date: 2023-09-06)

• Primary citation: Ducka, A.M.,Joel, P.,Popowicz, G.M.,Trybus, K.M.,Schleicher, M.,Noegel, A.A.,Huber, R.,Holak, T.A.,Sitar, T.; Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation.; Proc.Natl.Acad.Sci.USA, 107:11757-11762, 2010; PubMed: 20538977; DOI: 10.1073/pnas.1005347107

Experimental method

X-RAY DIFFRACTION (2 Å)