6NZ9
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![BU of 6nz9 by Molmil](/molmil-images/mine/6nz9) | Crystal structure of E. coli fumarase C bound to citrate at 1.53 angstrom resolution | 分子名称: | CITRIC ACID, Fumarate hydratase class II | 著者 | Stuttgen, G.M, May, J.F, Bhattcharyya, B, Weaver, T.M. | 登録日 | 2019-02-13 | 公開日 | 2019-09-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.528 Å) | 主引用文献 | Closed fumarase C active-site structures reveal SS Loop residue contribution in catalysis. Febs Lett., 594, 2020
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2XE8
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![BU of 2xe8 by Molmil](/molmil-images/mine/2xe8) | The complete reaction cycle of human phosphoglycerate kinase: The open ternary complex with 3PG and AMP-PNP | 分子名称: | 3-PHOSPHOGLYCERIC ACID, PHOSPHOGLYCERATE KINASE 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | 著者 | Cliff, M.J, Baxter, N.J, Blackburn, G.M, Merli, A, Vas, M, Waltho, J.P, Bowler, M.W. | 登録日 | 2010-05-11 | 公開日 | 2011-01-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | A Spring Loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase. J.Biol.Chem., 286, 2011
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2XE7
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![BU of 2xe7 by Molmil](/molmil-images/mine/2xe7) | The complete reaction cycle of human phosphoglycerate kinase: The open ternary complex with 3PG and ADP | 分子名称: | 3-PHOSPHOGLYCERIC ACID, ADENOSINE-5'-DIPHOSPHATE, PHOSPHOGLYCERATE KINASE 1 | 著者 | Cliff, M.J, Baxter, N.J, Blackburn, G.M, Merli, A, Vas, M, Waltho, J.P, Bowler, M.W. | 登録日 | 2010-05-11 | 公開日 | 2011-01-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A Spring Loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase. J.Biol.Chem., 286, 2011
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4OUD
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![BU of 4oud by Molmil](/molmil-images/mine/4oud) | Engineered tyrosyl-tRNA synthetase with the nonstandard amino acid L-4,4-biphenylalanine | 分子名称: | TYROSINE, Tyrosyl-tRNA synthetase | 著者 | Takeuchi, R, Mandell, D.J, Lajoie, M.J, Church, G.M, Stoddard, B.L. | 登録日 | 2014-02-16 | 公開日 | 2015-01-28 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Biocontainment of genetically modified organisms by synthetic protein design. Nature, 518, 2015
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4PTC
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![BU of 4ptc by Molmil](/molmil-images/mine/4ptc) | Structure of a carboxamide compound (3) (2-{2-[(CYCLOPROPYLCARBONYL)AMINO]PYRIDIN-4-YL}-4-OXO-4H-1LAMBDA~4~,3-THIAZOLE-5-CARBOXAMIDE) to GSK3b | 分子名称: | 2-[2-(cyclopropylcarbonylamino)pyridin-4-yl]-4-methoxy-1,3-thiazole-5-carboxamide, Glycogen synthase kinase-3 beta | 著者 | Lewis, H.A, Sivaprakasam, P, Kish, K, Pokross, M, Dubowchik, G.M. | 登録日 | 2014-03-10 | 公開日 | 2015-04-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.711 Å) | 主引用文献 | Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core. Bioorg.Med.Chem.Lett., 25, 2015
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4P5J
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![BU of 4p5j by Molmil](/molmil-images/mine/4p5j) | Crystal structure of the tRNA-like structure from Turnip Yellow Mosaic Virus (TYMV), a tRNA mimicking RNA | 分子名称: | IRIDIUM HEXAMMINE ION, MAGNESIUM ION, SPERMINE, ... | 著者 | Colussi, T.M, Costantino, D.A, Hammond, J.A, Ruehle, G.M, Nix, J.C, Kieft, J.S. | 登録日 | 2014-03-17 | 公開日 | 2014-06-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9912 Å) | 主引用文献 | The structural basis of transfer RNA mimicry and conformational plasticity by a viral RNA. Nature, 511, 2014
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4P4R
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![BU of 4p4r by Molmil](/molmil-images/mine/4p4r) | Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergic Hypersensitivity and Autoimmunity | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DP alpha 1 chain, ... | 著者 | Clayton, G.M, Crawford, F, Kappler, J.W. | 登録日 | 2014-03-13 | 公開日 | 2014-07-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell, 158, 2014
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4QQB
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![BU of 4qqb by Molmil](/molmil-images/mine/4qqb) | Structural basis for the assembly of the SXL-UNR translation regulatory complex | 分子名称: | Protein sex-lethal, Upstream of N-ras, isoform A, ... | 著者 | Hennig, J, Popowicz, G.M, Sattler, M. | 登録日 | 2014-06-27 | 公開日 | 2014-09-03 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for the assembly of the Sxl-Unr translation regulatory complex. Nature, 515, 2014
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4RZT
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![BU of 4rzt by Molmil](/molmil-images/mine/4rzt) | Lac repressor engineered to bind sucralose, sucralose-bound tetramer | 分子名称: | 4-chloro-4-deoxy-alpha-D-galactopyranose-(1-2)-1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose, Lac repressor | 著者 | Arbing, M.A, Cascio, D, Sawaya, M.R, Kosuri, S, Church, G.M. | 登録日 | 2014-12-24 | 公開日 | 2015-12-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Engineering an allosteric transcription factor to respond to new ligands. Nat.Methods, 13, 2016
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7XMV
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![BU of 7xmv by Molmil](/molmil-images/mine/7xmv) | E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A(AMP/ADP) filament bound with ADP, AMP and R5P | 分子名称: | 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Hu, H.H, Lu, G.M, Chang, C.C, Liu, J.L. | 登録日 | 2022-04-27 | 公開日 | 2022-06-29 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Filamentation modulates allosteric regulation of PRPS. Elife, 11, 2022
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7XN3
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![BU of 7xn3 by Molmil](/molmil-images/mine/7xn3) | E.coli phosphoribosylpyrophosphate (PRPP) synthetase type B filament bound with Pi | 分子名称: | PHOSPHATE ION, Ribose-phosphate pyrophosphokinase | 著者 | Hu, H.H, Lu, G.M, Chang, C.C, Liu, J.L. | 登録日 | 2022-04-27 | 公開日 | 2022-06-29 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Filamentation modulates allosteric regulation of PRPS. Elife, 11, 2022
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7XMU
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![BU of 7xmu by Molmil](/molmil-images/mine/7xmu) | E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A filament bound with ADP, Pi and R5P | 分子名称: | 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Hu, H.H, Lu, G.M, Chang, C.C, Liu, J.L. | 登録日 | 2022-04-26 | 公開日 | 2022-06-29 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Filamentation modulates allosteric regulation of PRPS. Elife, 11, 2022
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4RZS
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![BU of 4rzs by Molmil](/molmil-images/mine/4rzs) | Lac repressor engineered to bind sucralose, unliganded tetramer | 分子名称: | GLYCEROL, Lac repressor | 著者 | Arbing, M.A, Cascio, D, Kosuri, S, Church, G.M. | 登録日 | 2014-12-24 | 公開日 | 2015-12-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Engineering an allosteric transcription factor to respond to new ligands. Nat.Methods, 13, 2016
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4P4K
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![BU of 4p4k by Molmil](/molmil-images/mine/4p4k) | Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between allergic hypersensitivity and auto immunity | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BERYLLIUM, HLA class II histocompatibility antigen, ... | 著者 | Clayton, G.M, Crawford, F, Kappler, J.W. | 登録日 | 2014-03-12 | 公開日 | 2014-07-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell, 158, 2014
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7UDT
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![BU of 7udt by Molmil](/molmil-images/mine/7udt) | cryo-EM structure of the rigor state wild type myosin-15-F-actin complex (symmetry expansion and re-centering) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Gong, R, Reynolds, M.J, Alushin, G.M. | 登録日 | 2022-03-20 | 公開日 | 2022-08-03 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia. Sci Adv, 8, 2022
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7UDU
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![BU of 7udu by Molmil](/molmil-images/mine/7udu) | cryo-EM structure of the ADP state wild type myosin-15-F-actin complex (symmetry expansion and re-centering) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Gong, R, Reynolds, M.J, Alushin, G.M. | 登録日 | 2022-03-20 | 公開日 | 2022-08-03 | 実験手法 | ELECTRON MICROSCOPY (4.15 Å) | 主引用文献 | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia. Sci Adv, 8, 2022
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4P57
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![BU of 4p57 by Molmil](/molmil-images/mine/4p57) | MHC TCR peptide complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | 著者 | Clayton, G.M, Crawford, F, Kappler, J.W. | 登録日 | 2014-03-14 | 公開日 | 2014-07-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell, 158, 2014
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4P5K
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![BU of 4p5k by Molmil](/molmil-images/mine/4p5k) | Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergy and Autoimmunity | 分子名称: | HLA class II histocompatibility antigen, DP alpha 1 chain, RAS peptide,HLA class II histocompatibility antigen, ... | 著者 | Clayton, G.M, Wang, Y, Crawford, F, Novikov, A, Wimberly, B.T, Kieft, J.S, Falta, M.T, Bowerman, N.A, Marrack, P, Fontenot, A.P, Dai, S, Kappler, J.W. | 登録日 | 2014-03-17 | 公開日 | 2015-01-21 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell, 158, 2014
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7UJ4
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![BU of 7uj4 by Molmil](/molmil-images/mine/7uj4) | Inhibition of Human Menin by SNDX-5613 | 分子名称: | 2-({4-[7-({(1r,4r)-4-[(ethanesulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N-ethyl-5-fluoro-N-(propan-2-yl)benzamide, Isoform 2 of Menin, MAGNESIUM ION | 著者 | McKeever, B.M, Kulkarni, S, McGeehan, G.M. | 登録日 | 2022-03-30 | 公開日 | 2022-12-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | MEN1 mutations mediate clinical resistance to menin inhibition. Nature, 615, 2023
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7WVF
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![BU of 7wvf by Molmil](/molmil-images/mine/7wvf) | ectoTLR3-mAb12-poly(I:C) complex | 分子名称: | RNA (46-MER), Toll-like receptor 3, mAb12 | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | 登録日 | 2022-02-10 | 公開日 | 2022-11-16 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand. Nat Commun, 13, 2022
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7WVJ
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![BU of 7wvj by Molmil](/molmil-images/mine/7wvj) | NT-mut(K117D,K139D,K145D) TLR3 -poly I:C complex | 分子名称: | RNA (46-MER), Toll-like receptor 3 | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | 登録日 | 2022-02-10 | 公開日 | 2022-11-16 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand. Nat Commun, 13, 2022
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7WV5
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![BU of 7wv5 by Molmil](/molmil-images/mine/7wv5) | ectoTLR3-poly(I:C) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RNA (46-MER), ... | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | 登録日 | 2022-02-09 | 公開日 | 2022-11-16 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand. Nat Commun, 13, 2022
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7WV4
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![BU of 7wv4 by Molmil](/molmil-images/mine/7wv4) | ectoTLR3-poly(I:C) cluster | 分子名称: | RNA (80-MER), Toll-like receptor 3 | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | 登録日 | 2022-02-09 | 公開日 | 2022-11-16 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand. Nat Commun, 13, 2022
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7WVE
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![BU of 7wve by Molmil](/molmil-images/mine/7wve) | CT-mut (D523K,D524K,E527K) TLR3-poly(I:C) complex | 分子名称: | RNA (46-MER), Toll-like receptor 3 | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | 登録日 | 2022-02-10 | 公開日 | 2022-11-16 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand. Nat Commun, 13, 2022
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7WV3
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![BU of 7wv3 by Molmil](/molmil-images/mine/7wv3) | Toll-like receptor3 linear cluster | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RNA (80-MER), ... | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | 登録日 | 2022-02-09 | 公開日 | 2022-11-16 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (2.26 Å) | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand. Nat Commun, 13, 2022
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