4RZT
Lac repressor engineered to bind sucralose, sucralose-bound tetramer
Summary for 4RZT
Entry DOI | 10.2210/pdb4rzt/pdb |
Related | 4RZS |
Related PRD ID | PRD_900090 |
Descriptor | Lac repressor, 4-chloro-4-deoxy-alpha-D-galactopyranose-(1-2)-1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose (3 entities in total) |
Functional Keywords | sucralose, laci, lac repressor, lactose operon repressor, protein design, allostery, escherichia coli, transcription |
Biological source | Escherichia coli |
Total number of polymer chains | 4 |
Total formula weight | 165124.49 |
Authors | Arbing, M.A.,Cascio, D.,Sawaya, M.R.,Kosuri, S.,Church, G.M. (deposition date: 2014-12-24, release date: 2015-12-23, Last modification date: 2024-02-28) |
Primary citation | Taylor, N.D.,Garruss, A.S.,Moretti, R.,Chan, S.,Arbing, M.A.,Cascio, D.,Rogers, J.K.,Isaacs, F.J.,Kosuri, S.,Baker, D.,Fields, S.,Church, G.M.,Raman, S. Engineering an allosteric transcription factor to respond to new ligands. Nat.Methods, 13:177-183, 2016 Cited by PubMed: 26689263DOI: 10.1038/nmeth.3696 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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