7WVF

ectoTLR3-mAb12-poly(I:C) complex

Summary for 7WVF

• Entry DOI: 10.2210/pdb7wvf/pdb
• Related: 7WV3 7WV4 7WV5 7WVE 7WVJ
• EMDB information: 32852
• Descriptor: Toll-like receptor 3, RNA (46-MER), mAb12, ... (4 entities in total)
• Functional Keywords: toll-like receptor, dsrna, innate immunity, receptor, immune system, immune system-rna complex, immune system/rna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 213696.09

Authors

Lim, C.S.,Jang, Y.H.,Lee, G.Y.,Han, G.M.,Lee, J.O. (deposition date: 2022-02-10, release date: 2022-11-16, Last modification date: 2022-12-07)

• Primary citation: Lim, C.S.,Jang, Y.H.,Lee, G.Y.,Han, G.M.,Jeong, H.J.,Kim, J.W.,Lee, J.O.; TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.; Nat Commun, 13:6876-6876, 2022; PubMed: 36371424; DOI: 10.1038/s41467-022-34602-0

Experimental method

ELECTRON MICROSCOPY (3.91 Å)