7WV3

Toll-like receptor3 linear cluster

Summary for 7WV3

• Entry DOI: 10.2210/pdb7wv3/pdb
• Related: 7WV4 7WV5 7WVE 7WVF 7WVJ
• EMDB information: 32844
• Descriptor: Toll-like receptor 3, RNA (80-MER), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: toll-like receptor, dsrna, innate immunity, receptor, immune system, immune system-rna complex, immune system/rna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 469834.03

Authors

Lim, C.S.,Jang, Y.H.,Lee, G.Y.,Han, G.M.,Lee, J.O. (deposition date: 2022-02-09, release date: 2022-11-16, Last modification date: 2022-12-07)

• Primary citation: Lim, C.S.,Jang, Y.H.,Lee, G.Y.,Han, G.M.,Jeong, H.J.,Kim, J.W.,Lee, J.O.; TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.; Nat Commun, 13:6876-6876, 2022; PubMed: 36371424; DOI: 10.1038/s41467-022-34602-0

Experimental method

ELECTRON MICROSCOPY (2.26 Å)