7WVJ
NT-mut(K117D,K139D,K145D) TLR3 -poly I:C complex
Summary for 7WVJ
Entry DOI | 10.2210/pdb7wvj/pdb |
Related | 7WV3 7WV4 7WV5 7WVE 7WVF |
EMDB information | 32853 |
Descriptor | Toll-like receptor 3, RNA (46-MER) (3 entities in total) |
Functional Keywords | toll-like receptor, dsrna, innate immunity, receptor, immune system, immune system-rna complex, immune system/rna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 185899.42 |
Authors | Lim, C.S.,Jang, Y.H.,Lee, G.Y.,Han, G.M.,Lee, J.O. (deposition date: 2022-02-10, release date: 2022-11-16, Last modification date: 2022-12-07) |
Primary citation | Lim, C.S.,Jang, Y.H.,Lee, G.Y.,Han, G.M.,Jeong, H.J.,Kim, J.W.,Lee, J.O. TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand. Nat Commun, 13:6876-6876, 2022 Cited by PubMed: 36371424DOI: 10.1038/s41467-022-34602-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.26 Å) |
Structure validation
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