3LAD
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3CV0
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![BU of 3cv0 by Molmil](/molmil-images/mine/3cv0) | Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to T. brucei Phosphoglucoisomerase (PGI) PTS1 peptide | 分子名称: | 1,2-ETHANEDIOL, Peroxisome targeting signal 1 receptor PEX5, T. brucei PGI PTS1 peptide Ac-FNELSHL | 著者 | Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J. | 登録日 | 2008-04-17 | 公開日 | 2008-06-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5. J.Mol.Biol., 381, 2008
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3DC6
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![BU of 3dc6 by Molmil](/molmil-images/mine/3dc6) | Crystal Structure of a manganese superoxide dismutases from Caenorhabditis elegans | 分子名称: | MANGANESE (II) ION, SULFATE ION, Superoxide dismutase [Mn] 1 | 著者 | Trinh, C.H, Hunter, T, Stewart, E.E, Phillips, S.E.V, Hunter, G.J. | 登録日 | 2008-06-03 | 公開日 | 2009-06-09 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Purification, crystallization and X-ray structures of the two manganese superoxide dismutases from Caenorhabditis elegans Acta Crystallogr.,Sect.F, 64, 2008
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5I23
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![BU of 5i23 by Molmil](/molmil-images/mine/5i23) | Crystal Structure of Agd31B, alpha-transglucosylase in Glycoside Hydrolase Family 31, in complex with Cyclophellitol Aziridine probe CF022 | 分子名称: | 1,2-ETHANEDIOL, 1-(8-{[(1S,2R,3S,4S,5R,6R)-2,3,4,5-tetrahydroxy-6-(hydroxymethyl)cyclohexyl]amino}octyl)triaza-1,2-dien-2-ium, Oligosaccharide 4-alpha-D-glucosyltransferase, ... | 著者 | Wu, L, Davies, G.J. | 登録日 | 2016-02-08 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Detection of Active Mammalian GH31 alpha-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes. Acs Cent.Sci., 2, 2016
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5INZ
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![BU of 5inz by Molmil](/molmil-images/mine/5inz) | Racemic structure of baboon theta defensin-2 | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Theta defensin-2, ... | 著者 | Wang, C.K, King, G.J, Conibear, A.C, Ramos, M.C, Craik, D.J. | 登録日 | 2016-03-08 | 公開日 | 2016-04-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.447 Å) | 主引用文献 | Mirror Images of Antimicrobial Peptides Provide Reflections on Their Functions and Amyloidogenic Properties. J.Am.Chem.Soc., 138, 2016
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3MJZ
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![BU of 3mjz by Molmil](/molmil-images/mine/3mjz) | The crystal structure of native FG41 MSAD | 分子名称: | FG41 Malonate Semialdehyde Decarboxylase | 著者 | Guo, Y, Serrano, H, Poelarends, G.J, Johnson, W.H.Jr, Hackert, M.L, Whitman, C.P. | 登録日 | 2010-04-13 | 公開日 | 2011-04-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Kinetic, Mutational, and Structural Analysis of Malonate Semialdehyde Decarboxylase from Coryneform Bacterium Strain FG41: Mechanistic Implications for the Decarboxylase and Hydratase Activities. Biochemistry, 52, 2013
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5C86
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![BU of 5c86 by Molmil](/molmil-images/mine/5c86) | Novel fungal alcohol oxidase with catalytic diversity among the AA5 family, apo form | 分子名称: | Kelch domain-containing protein | 著者 | Urresti, S, Yin, D.T, LaFond, M, Derikvand, F, Berrin, G.J, Henrissat, B, Walton, P.H, Brumer, H, Davies, G.J. | 登録日 | 2015-06-25 | 公開日 | 2015-07-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Structure-function characterization reveals new catalytic diversity in the galactose oxidase and glyoxal oxidase family. Nat Commun, 6, 2015
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5C92
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![BU of 5c92 by Molmil](/molmil-images/mine/5c92) | Novel fungal alcohol oxidase with catalytic diversity among the AA5 family, in complex with copper | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, COPPER (I) ION, ... | 著者 | Urresti, S, Yin, D.T, LaFond, M, Derikvand, F, Berrin, G.J, Henrissat, B, Walton, P.H, Brumer, H, Davies, G.J. | 登録日 | 2015-06-26 | 公開日 | 2015-07-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-function characterization reveals new catalytic diversity in the galactose oxidase and glyoxal oxidase family. Nat Commun, 6, 2015
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1X70
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![BU of 1x70 by Molmil](/molmil-images/mine/1x70) | HUMAN DIPEPTIDYL PEPTIDASE IV IN COMPLEX WITH A BETA AMINO ACID INHIBITOR | 分子名称: | (2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-A MINE, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kim, D, Wang, L, Beconi, M, Eiermann, G.J, Fisher, M.H, He, H, Hickey, G.J, Leiting, B, Lyons, K. | 登録日 | 2004-08-12 | 公開日 | 2005-01-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | (2R)-4-Oxo-4-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin- 7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: A Potent, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes J.Med.Chem., 48, 2005
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2BRS
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![BU of 2brs by Molmil](/molmil-images/mine/2brs) | EMBP Heparin complex | 分子名称: | 2-O-sulfo-beta-L-altropyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, EOSINOPHIL-GRANULE MAJOR BASIC PROTEIN, SULFATE ION | 著者 | Swaminathan, G.J, Myszka, D.G, Katsamba, P.S, Ohnuki, L.E, Gleich, G.J, Acharya, K.R. | 登録日 | 2005-05-11 | 公開日 | 2005-10-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Eosinophil-Granule Major Basic Protein, a C-Type Lectin, Binds Heparin Biochemistry, 44, 2005
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1W80
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![BU of 1w80 by Molmil](/molmil-images/mine/1w80) | Crystal structure of the alpha-adaptin appendage domain, from the AP2 adaptor complex, bound to 2 peptides from Synaptojanin170 | 分子名称: | ADAPTER-RELATED PROTEIN COMPLEX 2 ALPHA 2 SUBUNIT, BENZAMIDINE, CARBONATE ION, ... | 著者 | Ford, M.G.J, Praefcke, G.J.K, McMahon, H.T. | 登録日 | 2004-09-14 | 公開日 | 2004-10-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Evolving Nature of the Ap2 Alpha-Appendage Hub During Clathrin-Coated Vesicle Endocytosis. Embo J., 23, 2004
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4V08
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![BU of 4v08 by Molmil](/molmil-images/mine/4v08) | Inhibited dimeric pseudorabies virus protease pUL26N at 2 A resolution | 分子名称: | CHLORIDE ION, DIISOPROPYL PHOSPHONATE, MAGNESIUM ION, ... | 著者 | Zuehlsdorf, M, Werten, S, Palm, G.J, Hinrichs, W. | 登録日 | 2014-09-11 | 公開日 | 2015-07-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin Pul26N, a Herpesvirus Serine Protease Plos Pathog., 11, 2015
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4UU9
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![BU of 4uu9 by Molmil](/molmil-images/mine/4uu9) | Crystal structure of the human c5a in complex with MEDI7814 a neutralising antibody | 分子名称: | COMPLEMENT C5, MEDI7814, SULFATE ION | 著者 | Colley, C, Sridharan, S, Dobson, C, Popovic, B, Debreczeni, J.E, Hargreaves, D, Edwards, B, Brennan, J, England, L, Fung, S, An Eghobamien, L, Sivars, U, Woods, R, Flavell, L, Renshaw, G.J, Wickson, K, Wilkinson, T, Davies, R, Bonnell, J, Warrener, P, Howes, R, Vaughan, T. | 登録日 | 2014-07-25 | 公開日 | 2015-08-12 | 最終更新日 | 2019-02-27 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors. MAbs, 10, 2018
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4V27
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![BU of 4v27 by Molmil](/molmil-images/mine/4v27) | Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with mannose-alpha-1,3-isofagomine | 分子名称: | 1,2-ETHANEDIOL, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, GLYCOSYL HYDROLASE FAMILY 71, ... | 著者 | Hakki, Z, Bellmaine, S, Thompson, A.J, Speciale, G, Davies, G.J, Williams, S.J. | 登録日 | 2014-10-07 | 公開日 | 2014-12-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and Kinetic Dissection of the Endo-Alpha-1,2-Mannanase Activity of Bacterial Gh99 Glycoside Hydrolases from Bacteroides Spp. Chemistry, 21, 2015
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8CE3
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![BU of 8ce3 by Molmil](/molmil-images/mine/8ce3) | Crystal structure of MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase V) luminal domain with a Lys329-Ile345 loop truncation, in complex with 3D fragment 2548 | 分子名称: | (3~{S})-1-ethanoyl-3-(4-methylphenyl)piperidine-3-carboxylic acid, 1,2-ETHANEDIOL, Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, ... | 著者 | Gilio, A.K, Darby, J.F, Wu, L, Davies, G.J. | 登録日 | 2023-02-01 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | A Modular 3-D Fragment Collection: Design, Synthesis and Screening To Be Published
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8IK0
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8IK3
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8ISN
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![BU of 8isn by Molmil](/molmil-images/mine/8isn) | HLA-A24 in complex with modified 9mer WT1 peptide | 分子名称: | Beta-2-microglobulin, CYS-TYR-THR-TRP-ASN-GLN-MET-ASN-LEU, GLYCEROL, ... | 著者 | Bekker, G.J, Numoto, N, Kawasaki, M, Hayashi, T, Yabuno, S, Kozono, Y, Shimizu, T, Kozono, H, Ito, N, Oda, M, Kamiya, N. | 登録日 | 2023-03-21 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Elucidation of binding mechanism, affinity, and complex structure between mWT1 tumor-associated antigen peptide and HLA-A*24:02. Protein Sci., 32, 2023
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6MBG
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7ZG6
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![BU of 7zg6 by Molmil](/molmil-images/mine/7zg6) | TacA1 antitoxin | 分子名称: | DUF1778 domain-containing protein, MAGNESIUM ION | 著者 | Grabe, G.J, Morgan, R.M.L, Helaine, S. | 登録日 | 2022-04-01 | 公開日 | 2023-10-11 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Molecular stripping underpins derepression of a toxin-antitoxin system. Nat.Struct.Mol.Biol., 2024
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7ZG5
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![BU of 7zg5 by Molmil](/molmil-images/mine/7zg5) | The crystal structure of Salmonella TacAT3-DNA complex | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Acetyltransferase, BARIUM ION, ... | 著者 | Grabe, G.J, Morgan, R.M.L, Helaine, S. | 登録日 | 2022-04-01 | 公開日 | 2023-10-11 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular stripping underpins derepression of a toxin-antitoxin system. Nat.Struct.Mol.Biol., 2024
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6MBF
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![BU of 6mbf by Molmil](/molmil-images/mine/6mbf) | GphF Dehydratase 1 | 分子名称: | GphF Dehydratase 1, MAGNESIUM ION | 著者 | Dodge, G.J, Smith, J.L. | 登録日 | 2018-08-29 | 公開日 | 2018-09-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.543 Å) | 主引用文献 | Molecular Basis for Olefin Rearrangement in the Gephyronic Acid Polyketide Synthase. ACS Chem. Biol., 13, 2018
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8A3H
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![BU of 8a3h by Molmil](/molmil-images/mine/8a3h) | Cellobiose-derived imidazole complex of the endoglucanase cel5A from Bacillus agaradhaerens at 0.97 A resolution | 分子名称: | (5R,6R,7R,8S)-7,8-dihydroxy-5-(hydroxymethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-6-yl beta-D-glucopyranoside, ACETATE ION, GLYCEROL, ... | 著者 | Varrot, A, Schulein, M, Pipelier, M, Vasella, A, Davies, G.J. | 登録日 | 1999-01-20 | 公開日 | 2000-01-21 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | 主引用文献 | Lateral Protonation of a Glycosidase Inhibitor. Structure of the Bacillus agaradhaerens Cel5A in Complex with a Cellobiose-Derived Imidazole at 0.97 A Resolution J.Am.Chem.Soc., 121, 1999
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6MBH
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1PHP
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