8CE3

Crystal structure of MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase V) luminal domain with a Lys329-Ile345 loop truncation, in complex with 3D fragment 2548

Summary for 8CE3

• Entry DOI: 10.2210/pdb8ce3/pdb
• Descriptor: Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, 1,2-ETHANEDIOL, (3~{S})-1-ethanoyl-3-(4-methylphenyl)piperidine-3-carboxylic acid, ... (5 entities in total)
• Functional Keywords: glycosyltransferase, fragment, carbohydrate
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 119938.42

Authors

Gilio, A.K.,Darby, J.F.,Wu, L.,Davies, G.J. (deposition date: 2023-02-01, release date: 2024-02-21)

• Primary citation: Downes, T.D.,Jones, S.P.,Firth, J.D.,Darby, J.F.,Gilio, A.K.,Klein, H.F.,Blakemore, D.C.,de Fusco, C.,Roughley, S.D.,Vidler, L.R.,Whatton, M.A.,Woolford, A.J.A.,Wrigley, G.L.,Hubbard, R.E.,Wu, L.,Davies, G.J.,O'Brien, P.; A Modular 3-D Fragment Collection: Design, Synthesis and Screening; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.89 Å)