4V27

Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with mannose-alpha-1,3-isofagomine

Summary for 4V27

Entry DOI	10.2210/pdb4v27/pdb
Related	4V1R 4V1S 4V28
Descriptor	GLYCOSYL HYDROLASE FAMILY 71, alpha-D-mannopyranose, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, ... (5 entities in total)
Functional Keywords	hydrolase, gh99, cazy, mannan, bacteroides, polysaccharide utilisation, enzyme-carbohydrate interaction, inhibitor, glycosidase inhibition
Biological source	BACTEROIDES XYLANISOLVENS
Total number of polymer chains	1
Total formula weight	43992.80
Authors	Hakki, Z.,Bellmaine, S.,Thompson, A.J.,Speciale, G.,Davies, G.J.,Williams, S.J. (deposition date: 2014-10-07, release date: 2014-12-24, Last modification date: 2024-01-10)
Primary citation	Hakki, Z.,Thompson, A.J.,Bellmaine, S.,Speciale, G.,Davies, G.J.,Williams, S.J. Structural and Kinetic Dissection of the Endo-Alpha-1,2-Mannanase Activity of Bacterial Gh99 Glycoside Hydrolases from Bacteroides Spp. Chemistry, 21:1966-, 2015 Cited by PubMed: 25487964 DOI: 10.1002/CHEM.201405539 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation