4FR2
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![BU of 4fr2 by Molmil](/molmil-images/mine/4fr2) | Alcohol dehydrogenase from Oenococcus oeni | Descriptor: | 1,3-propanediol dehydrogenase, NICKEL (II) ION | Authors: | Fodor, K, Skander, E, Wilmanns, M. | Deposit date: | 2012-06-26 | Release date: | 2013-06-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural and biochemical characterisation of a NAD(+)-dependent alcohol dehydrogenase from Oenococcus oeni as a new model molecule for industrial biotechnology applications. Appl.Microbiol.Biotechnol., 97, 2013
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4I8A
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![BU of 4i8a by Molmil](/molmil-images/mine/4i8a) | Alanine-glyoxylate aminotransferase variant S187F | Descriptor: | GLYCEROL, Serine-pyruvate aminotransferase | Authors: | Fodor, K, Oppici, E, Williams, C, Cellini, B, Wilmanns, M. | Deposit date: | 2012-12-03 | Release date: | 2013-05-01 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications. Proteins, 81, 2013
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2F91
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![BU of 2f91 by Molmil](/molmil-images/mine/2f91) | 1.2A resolution structure of a crayfish trypsin complexed with a peptide inhibitor, SGTI | Descriptor: | CADMIUM ION, CHLORIDE ION, Serine protease inhibitor I/II, ... | Authors: | Fodor, K, Harmat, V, Hetenyi, C, Kardos, J, Antal, J, Perczel, A, Patthy, A, Katona, G, Graf, L. | Deposit date: | 2005-12-05 | Release date: | 2006-04-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Enzyme:Substrate Hydrogen Bond Shortening during the Acylation Phase of Serine Protease Catalysis. Biochemistry, 45, 2006
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4KYO
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![BU of 4kyo by Molmil](/molmil-images/mine/4kyo) | Alanine-glyoxylate aminotransferase variant K390A in complex with the TPR domain of human Pex5p | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, Peroxisomal targeting signal 1 receptor, ... | Authors: | Fodor, K, Lou, Y, Wilmanns, M. | Deposit date: | 2013-05-29 | Release date: | 2014-11-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Ligand-Induced Compaction of the PEX5 Receptor-Binding Cavity Impacts Protein Import Efficiency into Peroxisomes. Traffic, 16, 2015
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4KXK
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![BU of 4kxk by Molmil](/molmil-images/mine/4kxk) | Alanine-glyoxylate aminotransferase variant K390A/K391A in complex with the TPR domain of human Pex5p | Descriptor: | BETA-MERCAPTOETHANOL, Peroxisomal targeting signal 1 receptor, SULFATE ION, ... | Authors: | Fodor, K, Lou, Y, Wilmanns, M. | Deposit date: | 2013-05-27 | Release date: | 2014-11-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Ligand-Induced Compaction of the PEX5 Receptor-Binding Cavity Impacts Protein Import Efficiency into Peroxisomes. Traffic, 16, 2015
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3R9A
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![BU of 3r9a by Molmil](/molmil-images/mine/3r9a) | Human alanine-glyoxylate aminotransferase in complex with the TPR domain of human PEX5P | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Peroxisomal targeting signal 1 receptor, Serine--pyruvate aminotransferase | Authors: | Fodor, K, Wilmanns, M. | Deposit date: | 2011-03-25 | Release date: | 2011-05-11 | Last modified: | 2012-05-02 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Molecular requirements for peroxisomal targeting of alanine-glyoxylate aminotransferase as an essential determinant in primary hyperoxaluria type 1 Plos Biol., 10, 2012
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4DJZ
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![BU of 4djz by Molmil](/molmil-images/mine/4djz) | Catalytic fragment of masp-1 in complex with its specific inhibitor developed by directed evolution on sgci scaffold | Descriptor: | Mannan-binding lectin serine protease 1 heavy chain, Mannan-binding lectin serine protease 1 light chain, Protease inhibitor SGPI-2 | Authors: | Heja, D, Harmat, V, Fodor, K, Wilmanns, M, Dobo, J, Kekesi, K.A, Zavodszky, P, Gal, P, Pal, G. | Deposit date: | 2012-02-03 | Release date: | 2012-04-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2. J.Biol.Chem., 287, 2012
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7PQO
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![BU of 7pqo by Molmil](/molmil-images/mine/7pqo) | Catalytic fragment of MASP-1 in complex with P1 site mutant ecotin | Descriptor: | Ecotin, GLYCEROL, Mannan-binding lectin serine protease 1, ... | Authors: | Harmat, V, Fodor, K, Heja, D. | Deposit date: | 2021-09-17 | Release date: | 2022-05-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.39 Å) | Cite: | Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation. J.Biol.Chem., 298, 2022
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7PQN
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![BU of 7pqn by Molmil](/molmil-images/mine/7pqn) | Catalytic fragment of MASP-2 in complex with ecotin | Descriptor: | Ecotin, GLYCEROL, Mannan-binding lectin serine protease 2 A chain, ... | Authors: | Harmat, V, Fodor, K, Heja, D. | Deposit date: | 2021-09-17 | Release date: | 2022-05-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.400015 Å) | Cite: | Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation. J.Biol.Chem., 298, 2022
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2JET
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![BU of 2jet by Molmil](/molmil-images/mine/2jet) | Crystal structure of a trypsin-like mutant (S189D , A226G) chymotrypsin. | Descriptor: | CHYMOTRYPSINOGEN B CHAIN A, CHYMOTRYPSINOGEN B CHAIN B, CHYMOTRYPSINOGEN B CHAIN C | Authors: | Jelinek, B, Katona, G, Fodor, K, Venekei, I, Graf, L. | Deposit date: | 2007-01-22 | Release date: | 2007-09-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Crystal Structure of a Trypsin-Like Mutant Chymotrypsin: The Role of Position 226 in the Activity and Specificity of S189D Chymotrypsin. Protein J., 27, 2008
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