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PDB: 92 results

4YTA
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BU of 4yta by Molmil
BOND LENGTH ANALYSIS OF ASP, GLU AND HIS RESIDUES IN TRYPSIN AT 1.2A RESOLUTION
Descriptor: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ...
Authors:Fisher, S.J, Helliwell, J.R, Blakeley, M.P, Cianci, M, McSweeny, S.
Deposit date:2015-03-17
Release date:2015-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Protonation-state determination in proteins using high-resolution X-ray crystallography: effects of resolution and completeness.
Acta Crystallogr. D Biol. Crystallogr., 68, 2012
6Y74
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BU of 6y74 by Molmil
X-ray crystal structure of human carbonic anhydrase IX catalytic domain.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CHLORIDE ION, ...
Authors:Fisher, S.Z, Koruza, K.
Deposit date:2020-02-28
Release date:2020-08-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Biophysical Characterization of Cancer-Related Carbonic Anhydrase IX
Int J Mol Sci, 21, 2020
6ZPE
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BU of 6zpe by Molmil
Nonstructural protein 10 (nsp10) from SARS CoV-2
Descriptor: CHLORIDE ION, GLYCEROL, Replicase polyprotein 1ab, ...
Authors:Fisher, S.Z, Kozielski, F.
Deposit date:2020-07-08
Release date:2020-10-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal Structure of Non-Structural Protein 10 from Severe Acute Respiratory Syndrome Coronavirus-2.
Int J Mol Sci, 21, 2020
3CX2
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BU of 3cx2 by Molmil
Crystal structure of the C1 domain of cardiac isoform of myosin binding protein-C at 1.3A
Descriptor: Myosin-binding protein C, cardiac-type
Authors:Fisher, S.J, Helliwell, J.R, Khurshid, S, Govada, L, Redwood, C, Squire, J.M, Chayen, N.E.
Deposit date:2008-04-23
Release date:2008-07-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:An investigation into the protonation states of the C1 domain of cardiac myosin-binding protein C
Acta Crystallogr.,Sect.D, 64, 2008
3UNX
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BU of 3unx by Molmil
Bond length analysis of asp, glu and his residues in subtilisin Carlsberg at 1.26A resolution
Descriptor: CALCIUM ION, GLYCEROL, SODIUM ION, ...
Authors:Fisher, S.J, Helliwell, J.R, Blakeley, M.P, Cianci, M, McSweeny, S.
Deposit date:2011-11-16
Release date:2012-06-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Protonation-state determination in proteins using high-resolution X-ray crystallography: effects of resolution and completeness.
Acta Crystallogr.,Sect.D, 68, 2012
4Y0J
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BU of 4y0j by Molmil
H/D exchanged human carbonic anhydrase II pH 6 room temperature neutron crystal structure.
Descriptor: Carbonic anhydrase 2, ZINC ION
Authors:Fisher, S.Z.
Deposit date:2015-02-06
Release date:2015-04-22
Last modified:2024-01-10
Method:NEUTRON DIFFRACTION (2 Å)
Cite:Joint neutron crystallographic and NMR solution studies of Tyr residue ionization and hydrogen bonding: Implications for enzyme-mediated proton transfer.
Proc.Natl.Acad.Sci.USA, 112, 2015
4PVN
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BU of 4pvn by Molmil
Neutron structure of human transthyretin (TTR) at room temperature to 2.3A resolution (monochromatic)
Descriptor: Transthyretin
Authors:Fisher, S.J, Blakeley, M.P, Haupt, M, Mason, S.A, Cooper, J.B, Mitchell, E.P, Forsyth, V.T.
Deposit date:2014-03-18
Release date:2014-11-12
Last modified:2024-03-20
Method:NEUTRON DIFFRACTION (2.3 Å), X-RAY DIFFRACTION
Cite:Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein
IUCrJ, 1, 2014
4PVM
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BU of 4pvm by Molmil
Neutron structure of human transthyretin (TTR) at room temperature to 2.0A resolution (Laue)
Descriptor: Transthyretin
Authors:Fisher, S.J, Blakeley, M.P, Haupt, M, Mason, S.A, Cooper, J.B, Mitchell, E.P, Forsyth, V.T.
Deposit date:2014-03-18
Release date:2014-11-12
Last modified:2024-03-20
Method:NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION
Cite:Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein
IUCrJ, 1, 2014
4PVL
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BU of 4pvl by Molmil
X-ray structure of human transthyretin (TTR) at room temperature to 1.9A resolution
Descriptor: Transthyretin
Authors:Fisher, S.J, Blakeley, M.P, Haupt, M, Mason, S.A, Cooper, J.B, Mitchell, E.P, Forsyth, V.T.
Deposit date:2014-03-18
Release date:2014-11-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein
IUCrJ, 1, 2014
3KKX
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BU of 3kkx by Molmil
Neutron structure of human carbonic anhydrase II
Descriptor: Carbonic anhydrase 2, ZINC ION
Authors:Fisher, S.Z, Langan, P.A.
Deposit date:2009-11-06
Release date:2010-01-12
Last modified:2023-09-06
Method:NEUTRON DIFFRACTION (2 Å)
Cite:Neutron structure of human carbonic anhydrase II: implications for proton transfer.
Biochemistry, 49, 2010
9FW2
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BU of 9fw2 by Molmil
SARS CoV-2 nsp10 in complex with the ExoN domain from nsp14
Descriptor: GLYCEROL, Guanine-N7 methyltransferase nsp14, Non-structural protein 11, ...
Authors:Fisher, S.Z.
Deposit date:2024-06-28
Release date:2024-07-10
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:SARS CoV-2 nsp10 in complex with the ExoN domain from nsp14
To Be Published
9FZK
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BU of 9fzk by Molmil
SARS CoV-2 nsp10 in complex with theExoN domain from nsp14
Descriptor: Guanine-N7 methyltransferase nsp14, Non-structural protein 11, ZINC ION
Authors:Fisher, S.Z.
Deposit date:2024-07-05
Release date:2024-07-17
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:SARS CoV-2 nsp10 in complex with theExoN domain from nsp14
To Be Published
9FZ4
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BU of 9fz4 by Molmil
SARS CoV-2 nsp10 in complex with theExoN domain from nsp14
Descriptor: GLYCEROL, Guanine-N7 methyltransferase nsp14, MAGNESIUM ION, ...
Authors:Fisher, S.Z.
Deposit date:2024-07-04
Release date:2024-07-17
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:SARS CoV-2 nsp10 in complex with theExoN domain from nsp14
To Be Published
4NY7
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BU of 4ny7 by Molmil
Bond length analysis of the PqqC Y175F mutant structure shows evidence for bound PQQ in the reduced form
Descriptor: CHLORIDE ION, GLYCEROL, PYRROLOQUINOLINE QUINONE, ...
Authors:Fisher, S.J, Puehringer, S.
Deposit date:2013-12-10
Release date:2015-03-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Bond length analysis of the PqqC Y175F mutant structure shows evidence for bound PQQ in the reduced form
To be Published
4Q49
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BU of 4q49 by Molmil
Room temperature neutron crystal structure of apo human carbonic anhydrase at pH 7.5
Descriptor: Carbonic anhydrase 2, ZINC ION
Authors:Fisher, S.Z, McKenna, R.
Deposit date:2014-04-14
Release date:2015-02-25
Last modified:2023-09-20
Method:NEUTRON DIFFRACTION (1.8 Å)
Cite:Joint neutron crystallographic and NMR solution studies of Tyr residue ionization and hydrogen bonding: Implications for enzyme-mediated proton transfer.
Proc.Natl.Acad.Sci.USA, 112, 2015
6FJJ
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BU of 6fjj by Molmil
Joint neutron and x-ray crystal structure of human carbonic anhydrase IX mimic (saccharin).
Descriptor: 1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE, Carbonic anhydrase 2, ZINC ION
Authors:Fisher, S.Z.
Deposit date:2018-01-22
Release date:2019-02-06
Last modified:2024-05-01
Method:NEUTRON DIFFRACTION (1.5 Å), X-RAY DIFFRACTION
Cite:Using neutron crystallography to elucidate the basis of selective inhibition of carbonic anhydrase by saccharin and a derivative.
J. Struct. Biol., 205, 2019
6GCY
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BU of 6gcy by Molmil
Joint neutron and x-ray crystal structure of human carbonic anhydrase IX mimic (saccharin-sugar conjugate complex)
Descriptor: Carbonic anhydrase 2, ZINC ION, [1-(1,1-dioxido-3-oxo-2,3-dihydro-1,2-benzothiazol-6-yl)-1H-1,2,3-triazol-4-yl]methyl alpha-L-idopyranoside
Authors:Fisher, S.Z, Koruza, K.
Deposit date:2018-04-20
Release date:2019-02-06
Last modified:2024-05-01
Method:NEUTRON DIFFRACTION (1.3 Å), X-RAY DIFFRACTION
Cite:Using neutron crystallography to elucidate the basis of selective inhibition of carbonic anhydrase by saccharin and a derivative.
J. Struct. Biol., 205, 2019
2QWS
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BU of 2qws by Molmil
Neutron and X-ray structural studies of short hydrogen bonds in Photoactive Yellow Protein (PYP)
Descriptor: 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein
Authors:Fisher, S.Z, Langan, P.
Deposit date:2007-08-10
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Neutron and X-ray structural studies of short hydrogen bonds in photoactive yellow protein (PYP)
Acta Crystallogr.,Sect.D, 63, 2007
6FJI
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BU of 6fji by Molmil
Joint neutron and x-ray crystal structure of human carbonic anhydrase IX mimic (apo).
Descriptor: Carbonic anhydrase 2, ZINC ION
Authors:Fisher, S.Z.
Deposit date:2018-01-22
Release date:2019-02-06
Last modified:2024-05-01
Method:NEUTRON DIFFRACTION (1.6 Å), X-RAY DIFFRACTION
Cite:Using neutron crystallography to elucidate the basis of selective inhibition of carbonic anhydrase by saccharin and a derivative.
J. Struct. Biol., 205, 2019
1XV8
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BU of 1xv8 by Molmil
Crystal Structure of Human Salivary Alpha-Amylase Dimer
Descriptor: Alpha-amylase, CALCIUM ION, CHLORIDE ION
Authors:Fisher, S.Z, Govindasamy, L, Tu, C.K, Silverman, D.N, Rajaniemi, H, McKenna, R.
Deposit date:2004-10-27
Release date:2005-10-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of Human Salivary Alpha-Amylase Dimer
To be Published
2NWZ
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BU of 2nwz by Molmil
Structural and kinetic effects of hydrophobic mutations on the active site of human carbonic anhydrase II
Descriptor: SULFATE ION, ZINC ION, carbonic anhydrase 2
Authors:Fisher, S.Z, McKenna, R.
Deposit date:2006-11-16
Release date:2007-04-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
2NXR
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BU of 2nxr by Molmil
Structural effects of hydrophobic mutations on the active site of human carbonic anhydrase II
Descriptor: SULFATE ION, ZINC ION, carbonic anhydrase 2
Authors:Fisher, S.Z, McKenna, R.
Deposit date:2006-11-19
Release date:2007-04-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
2NXS
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BU of 2nxs by Molmil
Structural and kinetic effects of hydrophobic mutations in the active site of human carbonic anhydrase II
Descriptor: SULFATE ION, ZINC ION, carbonic anhydrase 2
Authors:Fisher, S.Z, McKenna, R.
Deposit date:2006-11-19
Release date:2007-04-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
2NWP
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BU of 2nwp by Molmil
Structural and kinetic effects of hydrophobic mutations in the active site of human carbonic anhydrase II
Descriptor: SULFATE ION, ZINC ION, carbonic anhydrase 2
Authors:Fisher, S.Z, McKenna, R.
Deposit date:2006-11-16
Release date:2007-04-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
4G0C
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BU of 4g0c by Molmil
Neutron structure of acetazolamide-bound human carbonic anhydrase II reveal molecular details of drug binding.
Descriptor: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 2, ZINC ION
Authors:Fisher, S.Z, McKenna, R, Aggarwal, M.
Deposit date:2012-07-09
Release date:2012-09-19
Last modified:2023-09-13
Method:NEUTRON DIFFRACTION (2 Å)
Cite:Neutron diffraction of acetazolamide-bound human carbonic anhydrase II reveals atomic details of drug binding.
J.Am.Chem.Soc., 134, 2012

 

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