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PDB: 47 results

2Z7J
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BU of 2z7j by Molmil
Structural insights into de multifunctional VP3 protein of birnaviruses:gold derivative
Descriptor: Capsid assembly protein VP3, GOLD ION
Authors:Casanas, A, Navarro, A, Ferrer-Orta, C, Gonzalez, D, Rodriguez, J.F, Verdaguer, N.
Deposit date:2007-08-23
Release date:2008-02-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into the multifunctional protein VP3 of birnaviruses.
Structure, 16, 2008
6S2L
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BU of 6s2l by Molmil
FMDV 3D polymerase crystallized in presence of (F)uridylylated VPg peptide
Descriptor: GLYCEROL, Genome polyprotein
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2019-06-21
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:(F)uridylylated Peptides Linked to VPg1 of Foot-and- Mouth Disease Virus (FMDV): Design, Synthesis and X-Ray Crystallography of the Complexes with FMDV RNA-Dependent RNA Polymerase.
Molecules, 24, 2019
1KWM
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BU of 1kwm by Molmil
Human procarboxypeptidase B: Three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (TAFI)
Descriptor: CITRIC ACID, Procarboxypeptidase B, ZINC ION
Authors:Pereira, P.J.B, Segura-Martin, S, Ferrer-Orta, C, Vendrell, J, Aviles, F.-X, Coll, M, Gomis-Rueth, F.-X.
Deposit date:2002-01-30
Release date:2002-06-05
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Human procarboxypeptidase B: three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (TAFI).
J.Mol.Biol., 321, 2002
5JXS
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BU of 5jxs by Molmil
Mutant GC216/7AA of 3D polymerase from Foot-and-Mouth Disease Virus
Descriptor: MAGNESIUM ION, RNA Primer, RNA Template, ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2016-05-13
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Both cis and trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential for Viral RNA Replication.
J.Virol., 90, 2016
2JBA
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BU of 2jba by Molmil
PhoB response regulator receiver domain constitutively-active double mutant D53A and Y102C.
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB, SODIUM ION
Authors:Arribas-Bosacoma, R, Ferrer-Orta, C, Kim, S.-K, Blanco, A.G, Pereira, P.J.B, Gomis-Ruth, F.X, Wanner, B.L, Coll, M, Sola, M.
Deposit date:2006-12-05
Release date:2007-01-04
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The X-Ray Crystal Structures of Two Constitutively Active Mutants of the Escherichia Coli Phob Receiver Domain Give Insights Into Activation.
J.Mol.Biol., 366, 2007
6GVY
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BU of 6gvy by Molmil
Mutant M16A of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with an template -primer RNA
Descriptor: GLYCEROL, Genome polyprotein, RNA (5'-R(P*CP*CP*GP*GP*G)-3'), ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2018-06-21
Release date:2018-08-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis.
J. Virol., 92, 2018
5LOW
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BU of 5low by Molmil
Structure of the Ca2+-bound Rabphilin 3A C2B domain SNAP25 complex (P21 space group)
Descriptor: CALCIUM ION, GLYCEROL, Rabphilin-3A, ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2016-08-10
Release date:2017-06-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural characterization of the Rabphilin-3A-SNAP25 interaction.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3NKY
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BU of 3nky by Molmil
Structure of a mutant P44S of Foot-and-mouth disease Virus RNA-dependent RNA polymerase
Descriptor: 3D polymerase, MAGNESIUM ION
Authors:Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E.
Deposit date:2010-06-21
Release date:2011-05-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.
Plos Pathog., 6, 2010
3NMA
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BU of 3nma by Molmil
Mutant P169S of Foot-and-mouth disease Virus RNA dependent RNA-polymerase
Descriptor: 5'-R(*GP*GP*C)-3', 5'-R(P*CP*C)-3', Genome polyprotein, ...
Authors:Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E.
Deposit date:2010-06-22
Release date:2011-05-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.
Plos Pathog., 6, 2010
3NL0
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BU of 3nl0 by Molmil
Mutant P44S M296I of Foot-and-mouth disease Virus RNA-dependent RNA polymerase
Descriptor: 3D polymerase, 5'-R(*G*GP*GP*CP*CP*C)-3', 5'-R(P*UP*GP*GP*GP*CP*CP*C)-3', ...
Authors:Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E.
Deposit date:2010-06-21
Release date:2011-07-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.
Plos Pathog., 6, 2010
4LT7
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BU of 4lt7 by Molmil
Crystal structure of the c2a domain of rabphilin-3a in complex with a calcium
Descriptor: CALCIUM ION, Rabphilin-3A
Authors:Verdaguer, N, Ferrer-Orta, C, Buxaderas, M, Corbalan-Garcia, S, Perez-Sanchez, D, Guerrero-Valero, M, Luengo, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Guillen, J.
Deposit date:2013-07-23
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4NS0
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BU of 4ns0 by Molmil
The C2A domain of Rabphilin 3A in complex with PI(4,5)P2
Descriptor: Rabphilin-3A, SULFATE ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Guillen, J, Ferrer-Orta, C, Buxaderas, M, Perez-sanchez, D, Guerrero-Valero, M, Luengo-Gil, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Verdaguer, N, Corbalan-Garcia, S.
Deposit date:2013-11-27
Release date:2013-12-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4NYZ
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BU of 4nyz by Molmil
The EMCV 3Dpol structure with altered motif A conformation at 2.15A resolution
Descriptor: GLUTAMINE, GLYCEROL, Genome polyprotein, ...
Authors:Vives-adrian, L, Lujan, C, Ferrer-orta, C, Verdaguer, N.
Deposit date:2013-12-11
Release date:2014-03-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The crystal structure of a cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site
J.Virol., 88, 2014
4NZ0
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BU of 4nz0 by Molmil
The EMCV 3Dpol structure at 2.8A resolution
Descriptor: CHLORIDE ION, GLYCEROL, Genome polyprotein
Authors:Vives-adrian, L, Ferrer-orta, C, Verdaguer, N.
Deposit date:2013-12-11
Release date:2014-03-19
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of a cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site
J.Virol., 88, 2014
4NP9
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BU of 4np9 by Molmil
Structure of Rabphilin C2A domain bound to IP3
Descriptor: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Rabphilin-3A, SULFATE ION
Authors:Guillen, J, Ferrer-Orta, C, Buxaderas, M, Perez-Sanchez, D, Guerrero-Valero, M, Luengo-Gil, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Verdaguer, N, Corbalan-Garcia, S.
Deposit date:2013-11-21
Release date:2013-12-25
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4Y2A
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BU of 4y2a by Molmil
Crystal Structure of Coxsackie Virus B3 3D polymerase in complex with GPC-N114 inhibitor
Descriptor: 2,2'-[(4-chlorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), 3D polymerase, GLYCEROL, ...
Authors:Vives-Adrian, L, Ferrer-Orta, C, Verdaguer, N.
Deposit date:2015-02-09
Release date:2015-04-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
4Y34
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BU of 4y34 by Molmil
Crystal Structure of Coxsackievirus B3 3D polymerase in complex with GPC-N143
Descriptor: 2,2'-[(4-fluorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), 3D polymerase, GLYCEROL, ...
Authors:Vives-Adrian, L, Ferrer-Orta, C, Cerdaguer, N.
Deposit date:2015-02-10
Release date:2015-04-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
4Y2C
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BU of 4y2c by Molmil
M300V 3D polymerase mutant of EMCV
Descriptor: GLYCEROL, Genome polyprotein
Authors:Verdaguer, N, Ferrer-Orta, C, Vives-Adrian, L.
Deposit date:2015-02-09
Release date:2015-04-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
4Y3C
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BU of 4y3c by Molmil
I304V 3D polymerase mutant of EMCV
Descriptor: 3D polymerase, CHLORIDE ION, GLYCEROL
Authors:Verdaguer, N, Ferrer-Orta, C, Vives-Adrian, L.
Deposit date:2015-02-10
Release date:2015-04-01
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
4WZQ
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BU of 4wzq by Molmil
Mutant K20E of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with RNA
Descriptor: MANGANESE (II) ION, RNA dependent-RNA polymerase 3D, RNA template, ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2014-11-20
Release date:2015-05-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
4WZM
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BU of 4wzm by Molmil
Mutant K18E of RNA dependent RNA polymerase from Foot-and-Mouth Disease Virus complexed with RNA
Descriptor: ACETATE ION, GLYCEROL, MANGANESE (II) ION, ...
Authors:Verdaguer, N, Ferrer-Orta, C, de la Higuera, N.
Deposit date:2014-11-20
Release date:2015-05-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
4X2B
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BU of 4x2b by Molmil
K20A RNA dependent RNA polymerase mutant from Foot-and-Mouth disease Virus complexed with an RNA
Descriptor: MAGNESIUM ION, RNA dependent RNA polymerase, RNA primer, ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2014-11-26
Release date:2015-05-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
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