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PDB: 124 results

6ENV
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BU of 6env by Molmil
X-ray structure of Au2phen-encapsulated horse spleen apoferritin
Descriptor: CADMIUM ION, CHLORIDE ION, Ferritin light chain, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2017-10-06
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Ferritin nanocages loaded with gold ions induce oxidative stress and apoptosis in MCF-7 human breast cancer cells.
Dalton Trans, 46, 2017
6ENW
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BU of 6enw by Molmil
X-ray structure of Auoxo4-encapsulated horse spleen apoferritin
Descriptor: CADMIUM ION, CHLORIDE ION, Ferritin light chain, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2017-10-06
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Ferritin nanocages loaded with gold ions induce oxidative stress and apoptosis in MCF-7 human breast cancer cells.
Dalton Trans, 46, 2017
5OLE
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BU of 5ole by Molmil
X-ray structure of the adduct formed upon reaction of hen egg white lysozyme with a tetranuclear Pt-thiosemicarbazone compound
Descriptor: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Lysozyme C, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2017-07-27
Release date:2018-08-29
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Reactions of a tetranuclear Pt-thiosemicarbazone complex with model proteins.
J. Inorg. Biochem., 181, 2018
5OLD
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BU of 5old by Molmil
X-ray structure of the adduct formed upon reaction of ribonuclease A with a tetranuclear Pt-thiosemicarbazone compound
Descriptor: DIMETHYL SULFOXIDE, PLATINUM (II) ION, Ribonuclease pancreatic
Authors:Ferraro, G, Merlino, A.
Deposit date:2017-07-27
Release date:2018-08-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Reactions of a tetranuclear Pt-thiosemicarbazone complex with model proteins.
J. Inorg. Biochem., 181, 2018
9EO2
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BU of 9eo2 by Molmil
X-ray structure of the adduct formed upon reaction of picoplatin with lysozyme (structure B)
Descriptor: ACETATE ION, GLYCEROL, Lysozyme C, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2024-03-14
Release date:2024-05-22
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Picoplatin binding to proteins: X-ray structures and mass spectrometry data on the adducts with lysozyme and ribonuclease A.
Dalton Trans, 53, 2024
9ENZ
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BU of 9enz by Molmil
X-ray structure of the adduct formed upon reaction of picoplatin with lysozyme (structure A)
Descriptor: ACETATE ION, AMMONIA, Lysozyme C, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2024-03-14
Release date:2024-05-22
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Picoplatin binding to proteins: X-ray structures and mass spectrometry data on the adducts with lysozyme and ribonuclease A.
Dalton Trans, 53, 2024
9EO8
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BU of 9eo8 by Molmil
X-ray structure of the adduct formed upon reaction of picoplatin with bovine pancreatic ribonuclease (structure D)
Descriptor: AMMONIA, CHLORIDE ION, PLATINUM (II) ION, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2024-03-14
Release date:2024-05-22
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Picoplatin binding to proteins: X-ray structures and mass spectrometry data on the adducts with lysozyme and ribonuclease A.
Dalton Trans, 53, 2024
9EO5
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BU of 9eo5 by Molmil
X-ray structure of the adduct formed upon reaction of picoplatin with bovine pancreatic ribonuclease (structure C)
Descriptor: AMMONIA, PLATINUM (II) ION, Ribonuclease pancreatic
Authors:Ferraro, G, Merlino, A.
Deposit date:2024-03-14
Release date:2024-05-22
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Picoplatin binding to proteins: X-ray structures and mass spectrometry data on the adducts with lysozyme and ribonuclease A.
Dalton Trans, 53, 2024
7P8R
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BU of 7p8r by Molmil
X-ray structure of the adduct of a vanadium picolinate complex with RNase A at pH 5.1
Descriptor: Ribonuclease pancreatic, SULFATE ION, hydroxy(oxo)bis(pyridine-2-carboxylato-kappa~2~N,O)vanadium(3+)
Authors:Ferraro, G, Merlino, A.
Deposit date:2021-07-23
Release date:2021-12-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Spectroscopic/Computational Characterization and the X-ray Structure of the Adduct of the V IV O-Picolinato Complex with RNase A.
Inorg.Chem., 60, 2021
7PNI
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BU of 7pni by Molmil
X-ray structure of the adduct formed upon reaction of Pt(II) complex 2c with ribonuclease A
Descriptor: PLATINUM (II) ION, Ribonuclease pancreatic
Authors:Ferraro, G, Merlino, A.
Deposit date:2021-09-07
Release date:2021-10-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Reactions with Proteins of Three Novel Anticancer Platinum(II) Complexes Bearing N-Heterocyclic Ligands.
Int J Mol Sci, 22, 2021
7PNH
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BU of 7pnh by Molmil
X-ray structure of the adduct formed upon reaction of Pt(II) complex 2c with lysozyme
Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, IMIDAZOLE, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2021-09-07
Release date:2021-10-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Reactions with Proteins of Three Novel Anticancer Platinum(II) Complexes Bearing N-Heterocyclic Ligands.
Int J Mol Sci, 22, 2021
7NPM
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BU of 7npm by Molmil
X-ray structure of the adduct formed upon reaction of oxaliplatin with human angiogenin
Descriptor: Angiogenin, D(-)-TARTARIC ACID, PLATINUM (II) ION
Authors:Ferraro, G, Merlino, A.
Deposit date:2021-02-27
Release date:2022-03-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Oxaliplatin inhibits angiogenin proliferative and cell migration effects in prostate cancer cells.
J.Inorg.Biochem., 226, 2022
6Y3D
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BU of 6y3d by Molmil
X-ray structure of thermophilic C-phycocyanin from Galdiera phlegrea
Descriptor: ACETATE ION, C-phycocyanin alpha chain, C-phycocyanin beta chain, ...
Authors:Ferraro, G, Lucignano, R, Marseglia, A, Merlino, A.
Deposit date:2020-02-18
Release date:2020-12-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray structure of C-phycocyanin from Galdieria phlegrea: Determinants of thermostability and comparison with a C-phycocyanin in the entire phycobilisome.
Biochim Biophys Acta Bioenerg, 1861, 2020
8A2M
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BU of 8a2m by Molmil
X-ray structure of Ru(bpy)3]2+ complex (Ru1)-encapsulated human heavy chain ferritin
Descriptor: CHLORIDE ION, FE (III) ION, Ferritin heavy chain, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2022-06-03
Release date:2023-02-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:A new and efficient procedure to load bioactive molecules within the human heavy-chain ferritin nanocage.
Front Mol Biosci, 10, 2023
8A2L
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BU of 8a2l by Molmil
X-ray structure of TRIL-encapsulated human heavy chain ferritin
Descriptor: CHLORIDE ION, FE (III) ION, Ferritin heavy chain, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2022-06-03
Release date:2023-02-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:A new and efficient procedure to load bioactive molecules within the human heavy-chain ferritin nanocage.
Front Mol Biosci, 10, 2023
8A5N
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BU of 8a5n by Molmil
X-ray structure of human H-chain ferritin treated with SDS
Descriptor: CHLORIDE ION, FE (III) ION, Ferritin heavy chain, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2022-06-15
Release date:2023-02-08
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:A new and efficient procedure to load bioactive molecules within the human heavy-chain ferritin nanocage.
Front Mol Biosci, 10, 2023
5IX6
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BU of 5ix6 by Molmil
X-ray structure of Auoxo3-encapsulated horse spleen apoferritin
Descriptor: CADMIUM ION, Ferritin light chain, GOLD ION, ...
Authors:Ferraro, G, Pontillo, N, Merlino, A.
Deposit date:2016-03-23
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Gold-based drug encapsulation within a ferritin nanocage: X-ray structure and biological evaluation as a potential anticancer agent of the Auoxo3-loaded protein.
Chem.Commun.(Camb.), 52, 2016
8BOV
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BU of 8bov by Molmil
X-ray structure of the adduct formed upon reaction of the five-coordinate Pt(II) complex, 1-Me,Me, with HEWL at pH 7.5
Descriptor: 1-[1,3-dimethyl-4-(1~{H}-1,2,3-triazol-5-yl)imidazol-1-ium-2-yl]-1,2',11'-trimethyl-spiro[1$l^{6}-platinacycloprop-2-ene-1,15'-1,12-diaza-15$l^{6}-platinatetracyclo[10.2.1.0^{5,14}.0^{8,13}]pentadeca-2,4,6,8,10,13-hexaene], 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ...
Authors:Ferraro, G, Tito, G, Merlino, A.
Deposit date:2022-11-15
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Impact of Hydrophobic Chains in Five-Coordinate Glucoconjugate Pt(II) Anticancer Agents.
Int J Mol Sci, 24, 2023
8BOY
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BU of 8boy by Molmil
X-ray structure of the adduct formed upon reaction of the five-coordinate Pt(II) complex, 1-Me,Me, with HEWL at pH 4.0
Descriptor: 1-[1,3-dimethyl-4-(1~{H}-1,2,3-triazol-5-yl)imidazol-1-ium-2-yl]-1,2',11'-trimethyl-spiro[1$l^{6}-platinacycloprop-2-ene-1,15'-1,12-diaza-15$l^{6}-platinatetracyclo[10.2.1.0^{5,14}.0^{8,13}]pentadeca-2,4,6,8,10,13-hexaene], Lysozyme C, NITRATE ION, ...
Authors:Ferraro, G, Tito, G, Merlino, A.
Deposit date:2022-11-15
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Impact of Hydrophobic Chains in Five-Coordinate Glucoconjugate Pt(II) Anticancer Agents.
Int J Mol Sci, 24, 2023
5JVX
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BU of 5jvx by Molmil
X-ray structure of the adduct formed in the reaction between thaumatin and a gold carbene compound
Descriptor: (1-butyl-3-methyl-1,3-dihydro-2H-imidazol-2-ylidene)(chloro)gold, CHLORIDE ION, L(+)-TARTARIC ACID, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2016-05-11
Release date:2016-07-13
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:First Crystal Structure for a Gold Carbene-Protein Adduct.
Bioconjug.Chem., 27, 2016
5JLG
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BU of 5jlg by Molmil
The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and compound I, a piano-stool organometallic Ru(II) arene compound containing an O,S-chelating ligand
Descriptor: DIMETHYL SULFOXIDE, RUTHENIUM ION, Ribonuclease pancreatic, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2016-04-27
Release date:2016-08-03
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Unusual mode of protein binding by a cytotoxic pi-arene ruthenium(ii) piano-stool compound containing an O,S-chelating ligand.
Dalton Trans, 45, 2016
5IHG
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BU of 5ihg by Molmil
The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme a compound I, a platin(II) compound containing a O, S bidentate ligand
Descriptor: CHLORIDE ION, DIMETHYL SULFOXIDE, Lysozyme C, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2016-02-29
Release date:2016-12-07
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Platinum(ii) O,S complexes as potential metallodrugs against Cisplatin resistance.
Dalton Trans, 45, 2016
5II3
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BU of 5ii3 by Molmil
The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme and compound 3, a platin(II) compound containing a O, S bidentate ligand
Descriptor: CHLORIDE ION, DIMETHYL SULFOXIDE, Lysozyme C, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2016-03-01
Release date:2016-12-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Platinum(ii) O,S complexes as potential metallodrugs against Cisplatin resistance.
Dalton Trans, 45, 2016
8Q0R
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BU of 8q0r by Molmil
X-ray structure of MNEI mutant Mut9 (E23A, C41A, Y65R, S76Y)
Descriptor: ACETATE ION, Monellin chain B,Monellin chain A, SULFATE ION
Authors:Ferraro, G, Merlino, A, Lucignano, R, Picone, D.
Deposit date:2023-07-29
Release date:2024-02-07
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural insights and aggregation propensity of a super-stable monellin mutant: A new potential building block for protein-based nanostructured materials.
Int.J.Biol.Macromol., 254, 2024
8Q0S
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BU of 8q0s by Molmil
X-ray structure of the single chain monellin derivative MNEI
Descriptor: ACETATE ION, GLYCEROL, Monellin chain B,Monellin chain A, ...
Authors:Ferraro, G, Merlino, A, Lucignano, R, Picone, D.
Deposit date:2023-07-29
Release date:2024-02-07
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Structural insights and aggregation propensity of a super-stable monellin mutant: A new potential building block for protein-based nanostructured materials.
Int.J.Biol.Macromol., 254, 2024

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