7NPM

X-ray structure of the adduct formed upon reaction of oxaliplatin with human angiogenin

This is a non-PDB format compatible entry.

Summary for 7NPM

• Entry DOI: 10.2210/pdb7npm/pdb
• Descriptor: Angiogenin, PLATINUM (II) ION, D(-)-TARTARIC ACID, ... (4 entities in total)
• Functional Keywords: oxaliplatin, cancer, angiogenesis, protein metallation, angiogenin, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 14679.11

Authors

Ferraro, G.,Merlino, A. (deposition date: 2021-02-27, release date: 2022-03-23, Last modification date: 2024-02-07)

• Primary citation: Marzo, T.,Ferraro, G.,Cucci, L.M.,Pratesi, A.,Hansson, O.,Satriano, C.,Merlino, A.,La Mendola, D.; Oxaliplatin inhibits angiogenin proliferative and cell migration effects in prostate cancer cells.; J.Inorg.Biochem., 226:111657-111657, 2022; PubMed: 34784565; DOI: 10.1016/j.jinorgbio.2021.111657

Experimental method

X-RAY DIFFRACTION (1.86 Å)