8BOY
X-ray structure of the adduct formed upon reaction of the five-coordinate Pt(II) complex, 1-Me,Me, with HEWL at pH 4.0
This is a non-PDB format compatible entry.
Summary for 8BOY
Entry DOI | 10.2210/pdb8boy/pdb |
Descriptor | Lysozyme C, NITRATE ION, 1-[1,3-dimethyl-4-(1~{H}-1,2,3-triazol-5-yl)imidazol-1-ium-2-yl]-1,2',11'-trimethyl-spiro[1$l^{6}-platinacycloprop-2-ene-1,15'-1,12-diaza-15$l^{6}-platinatetracyclo[10.2.1.0^{5,14}.0^{8,13}]pentadeca-2,4,6,8,10,13-hexaene], ... (5 entities in total) |
Functional Keywords | platinum, five-coordinate, glucoconjugate, metallodrug, protein interaction, hydrolase |
Biological source | Gallus gallus (chicken) |
Total number of polymer chains | 1 |
Total formula weight | 15753.88 |
Authors | Ferraro, G.,Tito, G.,Merlino, A. (deposition date: 2022-11-15, release date: 2023-02-22, Last modification date: 2024-02-07) |
Primary citation | Annunziata, A.,Imbimbo, P.,Cucciolito, M.E.,Ferraro, G.,Langellotti, V.,Marano, A.,Melchiorre, M.,Tito, G.,Trifuoggi, M.,Monti, D.M.,Merlino, A.,Ruffo, F. Impact of Hydrophobic Chains in Five-Coordinate Glucoconjugate Pt(II) Anticancer Agents. Int J Mol Sci, 24:-, 2023 Cited by PubMed: 36768690DOI: 10.3390/ijms24032369 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.33 Å) |
Structure validation
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