6C3S
 
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3PZZ
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1L9L
 | | GRANULYSIN FROM HUMAN CYTOLYTIC T LYMPHOCYTES | | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ETHANOL, Granulysin, ... | | 著者 | Anderson, D.H, Sawaya, M.R, Cascio, D, Ernst, W, Krensky, A, Modlin, R, Eisenberg, D. | | 登録日 | 2002-03-25 | | 公開日 | 2002-11-06 | | 最終更新日 | 2017-09-13 | | 実験手法 | X-RAY DIFFRACTION (0.92 Å) | | 主引用文献 | Granulysin Crystal Structure and a Structure-Derived Lytic Mechanism
J.Mol.Biol., 325, 2002
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1MOP
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1N2I
 | | Crystal Structure of Pantothenate Synthetase from M. tuberculosis in complex with a reaction intermediate, pantoyl adenylate, different occupancies of pantoyl adenylate | | 分子名称: | ETHANOL, GLYCEROL, PANTOYL ADENYLATE, ... | | 著者 | Wang, S, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2002-10-22 | | 公開日 | 2003-04-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structures of a pantothenate
synthetase from M. tuberculosis and its
complexes with substrates and a
reaction intermediate
Protein Sci., 12, 2003
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1N2G
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1N2E
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1N2J
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1N2B
 | | Crystal Structure of a Pantothenate Synthetase from M. tuberculosis in complex with AMPCPP and pantoate, higher occupancy of pantoate and lower occupancy of AMPCPP in subunit A | | 分子名称: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ETHANOL, GLYCEROL, ... | | 著者 | Wang, S, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2002-10-22 | | 公開日 | 2003-04-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structures of a pantothenate
synthetase from M. tuberculosis and its
complexes with substrates and a
reaction intermediate
Protein Sci., 12, 2003
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1N2O
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3SGM
 | | Bromoderivative-2 of amyloid-related segment of alphaB-crystallin residues 90-100 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-crystallin B chain | | 著者 | Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. | | 登録日 | 2011-06-15 | | 公開日 | 2012-03-21 | | 実験手法 | X-RAY DIFFRACTION (1.7006 Å) | | 主引用文献 | Atomic view of a toxic amyloid small oligomer.
Science, 335, 2012
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3SGR
 | | Tandem repeat of amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Tandem repeat of amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L | | 著者 | Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. | | 登録日 | 2011-06-15 | | 公開日 | 2012-03-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Atomic view of a toxic amyloid small oligomer.
Science, 335, 2012
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3SGP
 | | Amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-crystallin B chain | | 著者 | Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. | | 登録日 | 2011-06-15 | | 公開日 | 2012-03-21 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.4016 Å) | | 主引用文献 | Atomic view of a toxic amyloid small oligomer.
Science, 335, 2012
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1JBM
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3OW9
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3Q4H
 | | Crystal structure of the Mycobacterium smegmatis EsxGH complex (MSMEG_0620-MSMEG_0621) | | 分子名称: | Low molecular weight protein antigen 7, Pe family protein | | 著者 | Chan, S, Harris, L, Kuo, E, Ahn, C, Zhou, T.T, Nguyen, L, Shin, A, Sawaya, M.R, Cascio, D, Arbing, M.A, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2010-12-23 | | 公開日 | 2011-01-26 | | 最終更新日 | 2014-05-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.
Plos One, 8, 2013
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3Q2X
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3PPD
 | | GGVLVN segment from Human Prostatic Acid Phosphatase Residues 260-265, involved in Semen-Derived Enhancer of Viral Infection | | 分子名称: | ACETIC ACID, GGVLVN peptide, amyloid forming segment, ... | | 著者 | Zhao, A, Sawaya, M.R, Eisenberg, D. | | 登録日 | 2010-11-24 | | 公開日 | 2011-06-29 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation.
Nature, 475, 2011
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3Q9I
 | | LVFFA segment from Alzheimer's Amyloid-Beta displayed on 42-membered macrocycle scaffold, bromide derivative | | 分子名称: | CHLORIDE ION, Cyclic pseudo-peptide LV(4BF)FA(ORN)(HAO)LK(ORN), GLYCEROL, ... | | 著者 | Liu, C, Sawaya, M.R, Eisenberg, D, Nowick, J.S, Cheng, P, Zheng, J. | | 登録日 | 2011-01-07 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic beta-Sheet Mimics.
J.Am.Chem.Soc., 133, 2011
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3Q9H
 | | LVFFA segment from Alzheimer's Amyloid-Beta displayed on 42-membered macrocycle scaffold | | 分子名称: | 1,4-BUTANEDIOL, Cyclic pseudo-peptide LVFFA(ORN)(HAO)LK(ORN), GLYCEROL, ... | | 著者 | Liu, C, Sawaya, M.R, Eisenberg, D, Nowick, J.S, Cheng, P, Zheng, J. | | 登録日 | 2011-01-07 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic beta-Sheet Mimics.
J.Am.Chem.Soc., 133, 2011
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3SGN
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3N3E
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1HTQ
 | | Multicopy crystallographic structure of a relaxed glutamine synthetase from Mycobacterium tuberculosis | | 分子名称: | ADENOSINE MONOPHOSPHATE, CITRIC ACID, MANGANESE (II) ION, ... | | 著者 | Gill, H.S, Pfluegl, G.M, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2001-01-01 | | 公開日 | 2002-07-24 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Multicopy crystallographic refinement of a relaxed glutamine synthetase from Mycobacterium tuberculosis highlights flexible loops in the enzymatic mechanism and its regulation.
Biochemistry, 41, 2002
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3NHC
 | | GYMLGS segment 127-132 from human prion with M129 | | 分子名称: | Major prion protein | | 著者 | Apostol, M.I, Eisenberg, D. | | 登録日 | 2010-06-14 | | 公開日 | 2010-08-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease.
J.Biol.Chem., 285, 2010
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3NI3
 | | 54-Membered ring macrocyclic beta-sheet peptide | | 分子名称: | 54-membered ring macrocyclic beta-sheet peptide, ISOPROPYL ALCOHOL | | 著者 | Sawaya, M.R, Eisenberg, D, Nowick, J.S, Korman, T.P, Khakshoor, O. | | 登録日 | 2010-06-15 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | | 主引用文献 | X-ray crystallographic structure of an artificial beta-sheet dimer.
J.Am.Chem.Soc., 132, 2010
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