3Q9H

LVFFA segment from Alzheimer's Amyloid-Beta displayed on 42-membered macrocycle scaffold

Summary for 3Q9H

Entry DOI	10.2210/pdb3q9h/pdb
Related	3Q9G 3Q9I 3Q9J
Descriptor	Cyclic pseudo-peptide LVFFA(ORN)(HAO)LK(ORN), SULFATE ION, GLYCEROL, ... (5 entities in total)
Functional Keywords	beta sheet tetramer, macrocyclic peptide, beta-sheet mimetic, protein fibril
Total number of polymer chains	8
Total formula weight	12440.61
Authors	Liu, C.,Sawaya, M.R.,Eisenberg, D.,Nowick, J.S.,Cheng, P.,Zheng, J. (deposition date: 2011-01-07, release date: 2011-06-08, Last modification date: 2023-11-15)
Primary citation	Liu, C.,Sawaya, M.R.,Cheng, P.N.,Zheng, J.,Nowick, J.S.,Eisenberg, D. Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic beta-Sheet Mimics. J.Am.Chem.Soc., 133:6736-6744, 2011 Cited by PubMed: 21473620 DOI: 10.1021/ja200222n PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation