1N2O

Crystal Structure of Pantothenate Synthetase from M. tuberculosis, low occupancy of beta-alanine at the pantoate binding sites

Summary for 1N2O

Entry DOI	10.2210/pdb1n2o/pdb
Related	1MOP 1N2B 1N2E 1N2G 1N2H 1N2I 1N2J
Descriptor	pantothenate synthetase, SULFATE ION, BETA-ALANINE, ... (4 entities in total)
Functional Keywords	structural genomics, rossmann fold, dimer, intersubunit beta sheet, psi, protein structure initiative, tb structural genomics consortium, tbsgc, ligase
Biological source	Mycobacterium tuberculosis
Cellular location	Cytoplasm (Potential): P0A5R0
Total number of polymer chains	2
Total formula weight	63370.51
Authors	Wang, S.,Eisenberg, D.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2002-10-23, release date: 2003-04-23, Last modification date: 2024-02-14)
Primary citation	Wang, S.,Eisenberg, D. Crystal structures of a pantothenate synthetase from M. tuberculosis and its complexes with substrates and a reaction intermediate Protein Sci., 12:1097-1108, 2003 Cited by PubMed: 12717031 DOI: 10.1110/ps.0241803 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation