3LY7
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7P85
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1CVR
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3DSZ
| Engineered human lipocalin 2 in complex with Y-DTPA | Descriptor: | N-{(1S,2S)-2-[bis(carboxymethyl)amino]cyclohexyl}-N-{(2R)-2-[bis(carboxymethyl)amino]-3-[4-({[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamothioyl}amino)phenyl]propyl}glycine, YTTRIUM (III) ION, engineered human lipocalin 2 | Authors: | Eichinger, A, Skerra, A. | Deposit date: | 2008-07-14 | Release date: | 2009-05-19 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | High-affinity recognition of lanthanide(III) chelate complexes by a reprogrammed human lipocalin 2 J.Am.Chem.Soc., 131, 2009
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3DTQ
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2HZR
| Crystal structure of human apolipoprotein D (ApoD) | Descriptor: | Apolipoprotein D | Authors: | Eichinger, A, Skerra, A. | Deposit date: | 2006-08-09 | Release date: | 2007-08-14 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insight into the dual ligand specificity and mode of high density lipoprotein association of apolipoprotein d. J.Biol.Chem., 282, 2007
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2HZQ
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3LY8
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3LYA
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3LY9
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4HH8
| Crystal structure of bovine butyrophilin | Descriptor: | Butyrophilin subfamily 1 member A1 | Authors: | Eichinger, A, Skerra, A. | Deposit date: | 2012-10-09 | Release date: | 2013-11-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The extracellular region of bovine butyrophilin exhibits high structural similarity to human myelin oligodendrocyte glycoprotein To be Published
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4IAX
| Engineered human lipocalin 2 (CL31) in complex with Y-DTPA | Descriptor: | N-{(1S,2S)-2-[bis(carboxymethyl)amino]cyclohexyl}-N-{(2R)-2-[bis(carboxymethyl)amino]-3-[4-({[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamothioyl}amino)phenyl]propyl}glycine, Neutrophil gelatinase-associated lipocalin, YTTRIUM (III) ION | Authors: | Eichinger, A, Skerra, A. | Deposit date: | 2012-12-07 | Release date: | 2013-06-19 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-guided engineering of Anticalins with improved binding behavior and biochemical characteristics for application in radio-immuno imaging and/or therapy J.Struct.Biol., 185, 2014
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4IAW
| Engineered human lipocalin 2 (C26) in complex with Y-DTPA | Descriptor: | N-{(1S,2S)-2-[bis(carboxymethyl)amino]cyclohexyl}-N-{(2R)-2-[bis(carboxymethyl)amino]-3-[4-({[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamothioyl}amino)phenyl]propyl}glycine, Neutrophil gelatinase-associated lipocalin, YTTRIUM (III) ION | Authors: | Eichinger, A, Skerra, A. | Deposit date: | 2012-12-07 | Release date: | 2013-06-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure-guided engineering of Anticalins with improved binding behavior and biochemical characteristics for application in radio-immuno imaging and/or therapy J.Struct.Biol., 185, 2014
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4MVL
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4MVI
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4MVK
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6QBB
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6GQZ
| Petrobactin-binding engineered lipocalin without ligand | Descriptor: | Neutrophil gelatinase-associated lipocalin | Authors: | Skerra, A, Eichinger, A. | Deposit date: | 2018-06-08 | Release date: | 2018-08-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Reprogramming Human Siderocalin To Neutralize Petrobactin, the Essential Iron Scavenger of Anthrax Bacillus. Angew. Chem. Int. Ed. Engl., 57, 2018
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8B50
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6GR0
| Petrobactin-binding engineered lipocalin in complex with gallium-petrobactin | Descriptor: | 4-[4-[3-[[3,4-bis(oxidanyl)phenyl]carbonylamino]propylamino]butylamino]-2-[2-[4-[3-[[3,4-bis(oxidanyl)phenyl]carbonylamino]propylamino]butylamino]-2-oxidanylidene-ethyl]-2-oxidanyl-4-oxidanylidene-butanoic acid, GALLIUM (III) ION, Neutrophil gelatinase-associated lipocalin | Authors: | Skerra, A, Eichinger, A. | Deposit date: | 2018-06-08 | Release date: | 2018-08-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Reprogramming Human Siderocalin To Neutralize Petrobactin, the Essential Iron Scavenger of Anthrax Bacillus. Angew. Chem. Int. Ed. Engl., 57, 2018
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5NKN
| Crystal structure of an Anticalin-colchicine complex | Descriptor: | N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide, Neutrophil gelatinase-associated lipocalin | Authors: | Skerra, A, Eichinger, A, Barkovskiy, M. | Deposit date: | 2017-03-31 | Release date: | 2018-04-04 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | An engineered lipocalin that tightly complexes the plant poison colchicine for use as antidote and in bioanalytical applications. Biol. Chem., 400, 2019
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5MHH
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5NBW
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6ZVF
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6Z2C
| Engineered lipocalin C3A5 in complex with a transition state analog | Descriptor: | 1,7,8,9,10,10-hexachloro-4-carboxypentyl-4-aza-tricyclo[5.2.1.0(2,6)]dec-8-ene-3,5-dione, Neutrophil gelatinase-associated lipocalin | Authors: | Skerra, A, Eichinger, A. | Deposit date: | 2020-05-15 | Release date: | 2021-05-26 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of an engineered lipocalin that catalyzes a Diels-Alder reaction To be published
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