4IAX
Engineered human lipocalin 2 (CL31) in complex with Y-DTPA
Summary for 4IAX
Entry DOI | 10.2210/pdb4iax/pdb |
Related | 3DSZ 3DTQ 4IAW |
Descriptor | Neutrophil gelatinase-associated lipocalin, N-{(1S,2S)-2-[bis(carboxymethyl)amino]cyclohexyl}-N-{(2R)-2-[bis(carboxymethyl)amino]-3-[4-({[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamothioyl}amino)phenyl]propyl}glycine, YTTRIUM (III) ION, ... (4 entities in total) |
Functional Keywords | beta-barrel, engineered lipocalin, binding protein, y-chx-a''-dtpa, strep-tag, transport protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P80188 |
Total number of polymer chains | 1 |
Total formula weight | 22370.17 |
Authors | Eichinger, A.,Skerra, A. (deposition date: 2012-12-07, release date: 2013-06-19, Last modification date: 2023-11-08) |
Primary citation | Eggenstein, E.,Eichinger, A.,Kim, H.J.,Skerra, A. Structure-guided engineering of Anticalins with improved binding behavior and biochemical characteristics for application in radio-immuno imaging and/or therapy J.Struct.Biol., 185:203-214, 2014 Cited by PubMed: 23542582DOI: 10.1016/j.jsb.2013.03.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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