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PDB: 1572 件

6XOZ
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Structure of human PYCR1 complexed with L-tetrahydro-2-furoic acid
分子名称: CHLORIDE ION, Pyrroline-5-carboxylate reductase 1, mitochondrial, ...
著者Tanner, J.J, Christensen, E.M.
登録日2020-07-07
公開日2020-11-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1.
J.Biol.Chem., 295, 2020
1HJL
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Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis protein MobA
分子名称: CITRIC ACID, LITHIUM ION, MOLYBDOPTERIN-GUANINE DINUCLEOTIDE BIOSYNTHESIS PROTEIN A
著者Guse, A, Stevenson, C.E.M, Kuper, J, Buchanan, G, Schwarz, G, Mendel, R.R, Lawson, D.M, Palmer, T.
登録日2003-02-27
公開日2003-05-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis Protein Moba
J.Biol.Chem., 278, 2003
1HJJ
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Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis protein MobA
分子名称: CITRIC ACID, LITHIUM ION, MOLYBDOPTERIN-GUANINE DINUCLEOTIDE BIOSYNTHESIS PROTEIN A
著者Guse, A, Stevenson, C.E.M, Kuper, J, Buchanan, G, Schwarz, G, Mendel, R.R, Lawson, D.M, Palmer, T.
登録日2003-02-27
公開日2003-05-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis Protein Moba
J.Biol.Chem., 278, 2003
8UBG
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DpHF19 filament
分子名称: DpHF19,Green fluorescent protein (Fragment)
著者Lynch, E.M, Shen, H, Kollman, J.M, Baker, D.
登録日2023-09-22
公開日2024-04-10
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献De novo design of pH-responsive self-assembling helical protein filaments.
Nat Nanotechnol, 19, 2024
8TQE
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XptA2 wild type
分子名称: XptA2
著者Martin, C.L, Binshtein, E.M, Aller, S.G.
登録日2023-08-07
公開日2023-09-27
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structures of the Insecticidal Toxin Complex Subunit XptA2 Highlight Roles for Flexible Domains.
Int J Mol Sci, 24, 2023
6XP2
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Structure of human PYCR1 complexed with L-thiazolidine-4-carboxylate
分子名称: Pyrroline-5-carboxylate reductase 1, mitochondrial, SULFATE ION, ...
著者Tanner, J.J, Christensen, E.M.
登録日2020-07-07
公開日2020-11-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1.
J.Biol.Chem., 295, 2020
5I2Y
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Crystal Structure of TPP1 K170A
分子名称: Adrenocortical dysplasia protein homolog
著者Nandakumar, J, Smith, E.M.
登録日2016-02-09
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and functional consequences of a disease mutation in the telomere protein TPP1.
Proc.Natl.Acad.Sci.USA, 113, 2016
3CXC
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The structure of an enhanced oxazolidinone inhibitor bound to the 50S ribosomal subunit of H. marismortui
分子名称: (3Z)-N-[(4E)-5-(4-{(5S)-5-[(acetylamino)methyl]-2-oxo-1,3-oxazolidin-3-yl}-2-fluorophenyl)pent-4-en-1-yl]-3-(4-methyl-2,6-dioxo-1,6-dihydropyrimidin-5(2H)-ylidene)propanamide, 23S RIBOSOMAL RNA, 5'-R(*CP*CP*A)-3', ...
著者Ippolito, J.A, Wang, D, Kanyo, Z.F, Duffy, E.M.
登録日2008-04-24
公開日2009-04-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
Bioorg.Med.Chem.Lett., 18, 2008
3DCQ
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LECB (PA-LII) in complex with the synthetic ligand 2G0
分子名称: (2S)-1-[(2S)-6-amino-2-({[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]acetyl}amino)hexanoyl]-N-[(1S)-1-carbamoyl-3-methylbutyl]pyrrolidine-2-carboxamide, CALCIUM ION, Fucose-binding lectin PA-IIL
著者Johansson, E.M, Crusz, S.A, Kolomiets, E, Buts, L, Kadam, R.U, Cacciarini, M, Bartels, K.M, Diggle, S.P, Camara, M, Williams, P, Loris, R, Nativi, C, Rosenau, F, Jaeger, K.E, Darbre, T, Reymond, J.L.
登録日2008-06-04
公開日2009-01-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Inhibition and dispersion of Pseudomonas aeruginosa biofilms by glycopeptide dendrimers targeting the fucose-specific lectin LecB.
Chem.Biol., 15, 2008
5V7X
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Crystal Structure of Myosin 1b residues 1-728 with bound sulfate and Calmodulin
分子名称: Calmodulin-1, SULFATE ION, Unconventional myosin-Ib
著者Zwolak, A, Shuman, H, Dominguez, R, Ostap, E.M.
登録日2017-03-20
公開日2018-02-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.141 Å)
主引用文献High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5I6Z
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X-ray structure of the ts2 human serotonin transporter
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, heavy chain, ...
著者Coleman, J.A, Green, E.M, Gouaux, E.
登録日2016-02-16
公開日2016-04-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.53 Å)
主引用文献X-ray structures and mechanism of the human serotonin transporter.
Nature, 532, 2016
5I73
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X-ray structure of the ts3 human serotonin transporter complexed with s-citalopram at the central and allosteric sites
分子名称: (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-AMINOHEXANOIC ACID, ...
著者Coleman, J.A, Green, E.M, Gouaux, E.
登録日2016-02-16
公開日2016-04-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献X-ray structures and mechanism of the human serotonin transporter.
Nature, 532, 2016
6XP0
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BU of 6xp0 by Molmil
Structure of human PYCR1 complexed with N-formyl L-proline
分子名称: 1-formyl-L-proline, Pyrroline-5-carboxylate reductase 1, mitochondrial
著者Tanner, J.J, Christensen, E.M.
登録日2020-07-07
公開日2020-11-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1.
J.Biol.Chem., 295, 2020
5W1F
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BU of 5w1f by Molmil
Crystal structure of Ni(II)- and Ca(II)-bound human calprotectin
分子名称: CALCIUM ION, NICKEL (II) ION, Protein S100-A8, ...
著者Nakashige, T.G, Drennan, C.L, Nolan, E.M.
登録日2017-06-03
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Nickel Sequestration by the Host-Defense Protein Human Calprotectin.
J. Am. Chem. Soc., 139, 2017
5IJC
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The crystal structure of mouse TLR4/MD-2/neoseptin-3 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, ...
著者Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B.
登録日2016-03-01
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
8UAO
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DpHF18 filament
分子名称: DpHF18
著者Lynch, E.M, Shen, H, Kollman, J.M, Baker, D.
登録日2023-09-21
公開日2024-04-10
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献De novo design of pH-responsive self-assembling helical protein filaments.
Nat Nanotechnol, 19, 2024
8UB3
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BU of 8ub3 by Molmil
DpHF7 filament
分子名称: DpHF7 filament
著者Lynch, E.M, Farrell, D, Shen, H, Kollman, J.M, DiMaio, F, Baker, D.
登録日2023-09-22
公開日2024-04-10
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献De novo design of pH-responsive self-assembling helical protein filaments.
Nat Nanotechnol, 19, 2024
8TUQ
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BU of 8tuq by Molmil
STL Polyomavirus LTA NLS bound to importin alpha 2
分子名称: Importin subunit alpha-1, Large T antigen
著者Donnelly, C.M, Cross, E.M, Forwood, J.K, Alvisi, G.
登録日2023-08-17
公開日2024-02-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
8TUS
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BU of 8tus by Molmil
WU Polyomavirus LTA NLS bound to importin alpha 2
分子名称: Importin subunit alpha-1, Large T antigen
著者Donnelly, C.M, Cross, E.M, Forwood, J.K, Alvisi, G.
登録日2023-08-17
公開日2024-02-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
8SPJ
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BU of 8spj by Molmil
Crystal Structure of SARS-CoV-2 Main Protease (Mpro) N28T Mutant
分子名称: 3C-like proteinase nsp5
著者Kohaal, N, Lewandowski, E.M, Wang, J, Chen, Y.
登録日2023-05-03
公開日2023-05-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Crystal Structure of SARS-CoV-2 Main Protease (Mpro) N28T Mutant
To Be Published
5H83
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HETEROYOHIMBINE SYNTHASE HYS FROM CATHARANTHUS ROSEUS - APO FORM
分子名称: ZINC ION, heteroyohimbine synthase HYS
著者Stavrinides, A, Tatsis, E.C, Caputi, L, Foureau, E, Stevenson, C.E.M, Lawson, D.M, Courdavault, V, O'Connor, S.E.
登録日2015-12-23
公開日2016-07-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural investigation of heteroyohimbine alkaloid synthesis reveals active site elements that control stereoselectivity.
Nat Commun, 7, 2016
8SXO
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Crystal Structure of SARS-CoV-2 Main Protease (Mpro) H164I Mutant
分子名称: 3C-like proteinase nsp5
著者Kohaal, N, Lewandowski, E.M, Wang, J, Chen, Y.
登録日2023-05-23
公開日2023-06-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Crystal Structure of SARS-CoV-2 Main Protease (Mpro) H164I Mutant
To Be Published
5IRV
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BU of 5irv by Molmil
Human cytochrome P450 17A1 bound to inhibitor VT-464
分子名称: PROTOPORPHYRIN IX CONTAINING FE, Steroid 17-alpha-hydroxylase/17,20 lyase, VT-464
著者Scott, E.E, Petrunak, E.M.
登録日2016-03-14
公開日2017-03-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.098 Å)
主引用文献Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1.
Drug Metab. Dispos., 45, 2017
5I66
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X-ray structure of the Fab fragment of 8B6, a murine monoclonal antibody specific for the human serotonin transporter
分子名称: 8B6 antibody, heavy chain, light chain
著者Coleman, J.A, Green, E.M, Gouaux, E.
登録日2016-02-16
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.624 Å)
主引用文献X-ray structures and mechanism of the human serotonin transporter.
Nature, 532, 2016
6XP1
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Structure of human PYCR1 complexed with L-thiazolidine-2-carboxylate
分子名称: (2S)-1,3-thiazolidine-2-carboxylic acid, Pyrroline-5-carboxylate reductase 1, mitochondrial, ...
著者Tanner, J.J, Christensen, E.M.
登録日2020-07-07
公開日2020-11-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1.
J.Biol.Chem., 295, 2020

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