3CXC
The structure of an enhanced oxazolidinone inhibitor bound to the 50S ribosomal subunit of H. marismortui
Summary for 3CXC
| Entry DOI | 10.2210/pdb3cxc/pdb |
| Descriptor | 23S RIBOSOMAL RNA, RIBOSOMAL PROTEIN L10, RIBOSOMAL PROTEIN L10E, ... (38 entities in total) |
| Functional Keywords | 50s ribosomal subunit, oxazolidinone, ribosome |
| Biological source | Haloarcula marismortui More |
| Total number of polymer chains | 31 |
| Total formula weight | 1459563.32 |
| Authors | Ippolito, J.A.,Wang, D.,Kanyo, Z.F.,Duffy, E.M. (deposition date: 2008-04-24, release date: 2009-04-28, Last modification date: 2023-08-30) |
| Primary citation | Zhou, J.,Bhattacharjee, A.,Chen, S.,Chen, Y.,Duffy, E.,Farmer, J.,Goldberg, J.,Hanselmann, R.,Ippolito, J.A.,Lou, R.,Orbin, A.,Oyelere, A.,Salvino, J.,Springer, D.,Tran, J.,Wang, D.,Wu, Y.,Johnson, G. Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics. Bioorg.Med.Chem.Lett., 18:6175-6178, 2008 Cited by PubMed: 18947996DOI: 10.1016/j.bmcl.2008.10.011 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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