8BIF
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8BID
| O-Methyltransferase Plu4890 (mutant H229N) in complex with SAH and AQ-270a | 分子名称: | 1-methoxy-3,8-bis(oxidanyl)anthracene-9,10-dione, CHLORIDE ION, GLYCEROL, ... | 著者 | Huber, E.M, Groll, M. | 登録日 | 2022-11-02 | 公開日 | 2023-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | A set of closely related methyltransferases for site-specific tailoring of anthraquinone pigments. Structure, 31, 2023
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2CCI
| Crystal structure of phospho-CDK2 Cyclin A in complex with a peptide containing both the substrate and recruitment sites of CDC6 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6 homolog, Cyclin-A2, ... | 著者 | Cheng, K.Y, Noble, M.E.M, Skamnaki, V, Brown, N.R, Lowe, E.D, Kontogiannis, L, Shen, K, Cole, P.A, Siligardi, G, Johnson, L.N. | 登録日 | 2006-01-16 | 公開日 | 2006-05-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The role of the phospho-CDK2/cyclin A recruitment site in substrate recognition. J. Biol. Chem., 281, 2006
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6Y6S
| Mouse Galactocerebrosidase complexed with galacto-noeurostegine GNS at pH 6.8 | 分子名称: | (1~{R},2~{S},3~{S},4~{R},5~{R})-4-(hydroxymethyl)-8-azabicyclo[3.2.1]octane-1,2,3-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Deane, J.E, McLoughlin, J. | 登録日 | 2020-02-27 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Bicyclic Form of galacto -Noeurostegine Is a Potent Inhibitor of beta-Galactocerebrosidase. Acs Med.Chem.Lett., 12, 2021
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6POG
| Crystal structure of the NELL2 EGF1-6-Robo3 FN1 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Wang, J, Pak, J.S, Ozkan, E. | 登録日 | 2019-07-03 | 公開日 | 2020-05-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.755 Å) | 主引用文献 | NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance. Nat Commun, 11, 2020
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6Y82
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6Y8H
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6PKD
| Myocilin OLF mutant N428D/D478H | 分子名称: | Myocilin, SODIUM ION | 著者 | Lieberman, R.L, Hill, S.E. | 登録日 | 2019-06-29 | 公開日 | 2019-09-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Calcium-ligand variants of the myocilin olfactomedin propeller selected from invertebrate phyla reveal cross-talk with N-terminal blade and surface helices. Acta Crystallogr D Struct Biol, 75, 2019
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8RH0
| Trimeric HSV-1F gB ectodomain in postfusion conformation with three bound HDIT102 Fab molecules. | 分子名称: | Envelope glycoprotein B, HDIT102 Fab heavy chain | 著者 | Kalbermatter, D, Seyfizadeh, N, Imhof, T, Ries, M, Mueller, C, Jenner, L, Blumenschein, E, Yendrzheyevskiy, A, Moog, K, Eckert, D, Engel, R, Diebolder, P, Chami, M, Krauss, J, Schaller, T, Arndt, M. | 登録日 | 2023-12-14 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | Development of a highly effective combination monoclonal antibody therapy against Herpes simplex virus. J.Biomed.Sci., 31, 2024
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8RH1
| Trimeric HSV-2F gB ectodomain in postfusion conformation with three bound HDIT101 Fab molecules. | 分子名称: | Envelope glycoprotein B, HDIT101 Fab heavy chain, HDIT101 Fab light chain | 著者 | Kalbermatter, D, Seyfizadeh, N, Imhof, T, Ries, M, Mueller, C, Jenner, L, Blumenschein, E, Yendrzheyevskiy, A, Moog, K, Eckert, D, Engel, R, Diebolder, P, Chami, M, Krauss, J, Schaller, T, Arndt, M. | 登録日 | 2023-12-14 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Development of a highly effective combination monoclonal antibody therapy against Herpes simplex virus. J.Biomed.Sci., 31, 2024
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3IAP
| E. coli (lacZ) beta-galactosidase (E416Q) | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | 著者 | Lo, S, Dugdale, M.L, Jeerh, N, Ku, T, Roth, N.J, Huber, R.E. | 登録日 | 2009-07-14 | 公開日 | 2009-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Studies of Glu-416 variants of beta-galactosidase (E. coli) show that the active site Mg(2+) is not important for structure and indicate that the main role of Mg (2+) is to mediate optimization of active site chemistry Protein J., 29, 2010
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4IVF
| Crystal structure of glutathione transferase homolog from Lodderomyces elongisporus, target EFI-501753, with two GSH per subunit | 分子名称: | CITRIC ACID, GLUTATHIONE, Putative uncharacterized protein | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2013-01-22 | 公開日 | 2013-02-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of glutathione transferase homolog from Lodderomyces elongisporus, target EFI-501753, with two GSH per subunit To be Published
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6PQ8
| Crystal structure of TLA-1 S70G extended spectrum Beta-lactamase in complex with clavulanic acid | 分子名称: | (2R,3Z,5R)-3-(2-HYDROXYETHYLIDENE)-7-OXO-4-OXA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, ACETATE ION, ASPARTIC ACID, ... | 著者 | Rudino-Pinera, E, Cifuentes-Castro, V.H, Rodriguez-Almazan, C. | 登録日 | 2019-07-08 | 公開日 | 2019-12-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The crystal structure of ESBL TLA-1 in complex with clavulanic acid reveals a second acylation site. Biochem.Biophys.Res.Commun., 522, 2020
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6PR3
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4EZF
| The Crystal Structure of a Human MitoNEET mutant with an Ala inserted between Asp 67 and Lys 68 | 分子名称: | CDGSH iron-sulfur domain-containing protein 1, FE2/S2 (INORGANIC) CLUSTER | 著者 | Baxter, E.L, Zuris, J.A, Wang, C, Axelrod, H.L, Cohen, A.E, Paddock, M.L, Nechushtai, R, Onuchic, J.N, Jennings, P.A. | 登録日 | 2012-05-02 | 公開日 | 2012-12-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | Allosteric control in a metalloprotein dramatically alters function. Proc.Natl.Acad.Sci.USA, 110, 2013
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6EWC
| Crystal structure of non-phosphorylated form of RLS PHOSPHOPEPTIDE BOUND TO HLA-A2 in complex with LILRB1 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Mohammed, F, Stones, D.H, Willcox, B.E. | 登録日 | 2017-11-03 | 公開日 | 2018-11-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Application of the immunoregulatory receptor LILRB1 as a crystallisation chaperone for human class I MHC complexes. J. Immunol. Methods, 464, 2019
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6PR1
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5KAA
| Protein Tyrosine Phosphatase 1B Delta helix 7, P185G mutant, open state | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Choy, M.S, Machado, L.E.S.F, Peti, W, Page, R. | 登録日 | 2016-06-01 | 公開日 | 2017-03-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.968 Å) | 主引用文献 | Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery. Mol. Cell, 65, 2017
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6PRG
| SBP RafE in complex with stachyose | 分子名称: | 1,2-ETHANEDIOL, ABC transporter sugar-binding protein, CITRIC ACID, ... | 著者 | Meier, E.P.W, Boraston, A.B. | 登録日 | 2019-07-10 | 公開日 | 2019-10-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Molecular analysis of an enigmaticStreptococcus pneumoniaevirulence factor: The raffinose-family oligosaccharide utilization system. J.Biol.Chem., 294, 2019
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1J54
| Structure of the N-terminal exonuclease domain of the epsilon subunit of E.coli DNA polymerase III at pH 5.8 | 分子名称: | 1,2-ETHANEDIOL, DNA polymerase III, epsilon chain, ... | 著者 | Hamdan, S, Carr, P.D, Brown, S.E, Ollis, D.L, Dixon, N.E. | 登録日 | 2002-01-22 | 公開日 | 2002-10-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Basis for Proofreading during Replication of the Escherichia coli Chromosome Structure, 10, 2002
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8RGZ
| Trimeric HSV-1F gB ectodomain in postfusion conformation with three bound HDIT101 Fab molecules. | 分子名称: | Envelope glycoprotein B, HDIT101 Fab heavy chain, HDIT101 Fab light chain | 著者 | Kalbermatter, D, Seyfizadeh, N, Imhof, T, Ries, M, Mueller, C, Jenner, L, Blumenschein, E, Yendrzheyevskiy, A, Moog, K, Eckert, D, Engel, R, Diebolder, P, Chami, M, Krauss, J, Schaller, T, Arndt, M. | 登録日 | 2023-12-14 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Development of a highly effective combination monoclonal antibody therapy against Herpes simplex virus. J.Biomed.Sci., 31, 2024
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4F4L
| Open Channel Conformation of a Voltage Gated Sodium Channel | 分子名称: | Ion transport protein | 著者 | McCusker, E.C, Bagneris, C, Naylor, C.E, Cole, A.R, D'Avanzo, N, Nichols, C.G, Wallace, B.A. | 登録日 | 2012-05-10 | 公開日 | 2012-10-03 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | 主引用文献 | Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing. Nat Commun, 3, 2012
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6PQZ
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5JPE
| Yeast-specific serine/threonine protein phosphatase (PPZ1) of Candida albicans | 分子名称: | CITRATE ANION, GLYCEROL, Serine/threonine-protein phosphatase | 著者 | Choy, M.S, Chen, E.H, Peti, W, Page, R. | 登録日 | 2016-05-03 | 公開日 | 2016-08-31 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.611 Å) | 主引用文献 | Molecular Insights into the Fungus-Specific Serine/Threonine Protein Phosphatase Z1 in Candida albicans. Mbio, 7, 2016
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8B9Y
| Cysteine Synthase from Trypanosoma cruzi with PLP and OAS | 分子名称: | Cysteine synthase, putative, GLYCEROL, ... | 著者 | Sowerby, K.V, Pohl, E. | 登録日 | 2022-10-10 | 公開日 | 2023-05-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis. Acta Crystallogr D Struct Biol, 79, 2023
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