4EZF

The Crystal Structure of a Human MitoNEET mutant with an Ala inserted between Asp 67 and Lys 68

Summary for 4EZF

Entry DOI	10.2210/pdb4ezf/pdb
Related	2QH7 3EW0 3LPQ 4F1E 4F28 4F2C
Descriptor	CDGSH iron-sulfur domain-containing protein 1, FE2/S2 (INORGANIC) CLUSTER (3 entities in total)
Functional Keywords	2fe-2s proteins, membrane, mitochondrion, signal-anchor, transmembrane, metal binding protein, mitoneet, protein frustration, cdgsh iron sulfur domain-containing protein 1, mitochondrial outer membrane
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion outer membrane; Single-pass type III membrane protein: Q9NZ45
Total number of polymer chains	2
Total formula weight	18390.45
Authors	Baxter, E.L.,Zuris, J.A.,Wang, C.,Axelrod, H.L.,Cohen, A.E.,Paddock, M.L.,Nechushtai, R.,Onuchic, J.N.,Jennings, P.A. (deposition date: 2012-05-02, release date: 2012-12-26, Last modification date: 2023-09-13)
Primary citation	Baxter, E.L.,Zuris, J.A.,Wang, C.,Vo, P.L.,Axelrod, H.L.,Cohen, A.E.,Paddock, M.L.,Nechushtai, R.,Onuchic, J.N.,Jennings, P.A. Allosteric control in a metalloprotein dramatically alters function. Proc.Natl.Acad.Sci.USA, 110:948-953, 2013 Cited by PubMed: 23271805 DOI: 10.1073/pnas.1208286110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.19 Å)

Structure validation