8B9Y
Cysteine Synthase from Trypanosoma cruzi with PLP and OAS
Summary for 8B9Y
| Entry DOI | 10.2210/pdb8b9y/pdb |
| Descriptor | Cysteine synthase, putative, O-ACETYLSERINE, alpha-D-ribofuranose, ... (6 entities in total) |
| Functional Keywords | chagas disease, amino acid synthesis, o-acetyl l-serine, pyridoxal 5-phosphate, transferase |
| Biological source | Trypanosoma cruzi |
| Total number of polymer chains | 4 |
| Total formula weight | 148069.92 |
| Authors | Sowerby, K.V.,Pohl, E. (deposition date: 2022-10-10, release date: 2023-05-31, Last modification date: 2024-02-07) |
| Primary citation | Sowerby, K.,Freitag-Pohl, S.,Murillo, A.M.,Silber, A.M.,Pohl, E. Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis. Acta Crystallogr D Struct Biol, 79:518-530, 2023 Cited by PubMed: 37204818DOI: 10.1107/S2059798323003613 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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