5YAL
 
 | | Ferulic acid esterase from Streptomyces cinnamoneus at 1.5 A resolution | | 分子名称: | ACETATE ION, Esterase, GLYCEROL, ... | | 著者 | Tamura, H, Uraji, M, Mizohata, E, Ogawa, K, Inoue, T, Hatanaka, T. | | 登録日 | 2017-09-01 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Loop of Streptomyces Feruloyl Esterase Plays an Important Role in the Enzyme's Catalyzing the Release of Ferulic Acid from Biomass.
Appl. Environ. Microbiol., 84, 2018
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7RQD
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site deacylated tRNA analog CACCA, P-site MTI-tripeptidyl-tRNA analog ACCA-ITM, and chloramphenicol at 2.50A resolution | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | | 著者 | Syroegin, E.A, Flemmich, L, Klepacki, D, Vazquez-Laslop, N, Micura, R, Polikanov, Y.S. | | 登録日 | 2021-08-06 | | 公開日 | 2022-01-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol.
Nat.Struct.Mol.Biol., 29, 2022
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3B1Q
 | | Structure of Burkholderia thailandensis nucleoside kinase (BthNK) in complex with inosine | | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ACETATE ION, INOSINE, ... | | 著者 | Yasutake, Y, Ota, H, Hino, E, Sakasegawa, S, Tamura, T. | | 登録日 | 2011-07-05 | | 公開日 | 2011-11-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structures of Burkholderia thailandensis nucleoside kinase: implications for the catalytic mechanism and nucleoside selectivity
Acta Crystallogr.,Sect.D, 67, 2011
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7RQE
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site deacylated tRNA analog CACCA, P-site MAI-tripeptidyl-tRNA analog ACCA-IAM, and chloramphenicol at 2.40A resolution | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | | 著者 | Syroegin, E.A, Flemmich, L, Klepacki, D, Vazquez-Laslop, N, Micura, R, Polikanov, Y.S. | | 登録日 | 2021-08-06 | | 公開日 | 2022-01-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol.
Nat.Struct.Mol.Biol., 29, 2022
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7RQA
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site MTI-tripeptidyl-tRNA analog ACCA-ITM at 2.40A resolution | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, ... | | 著者 | Syroegin, E.A, Flemmich, L, Klepacki, D, Vazquez-Laslop, N, Micura, R, Polikanov, Y.S. | | 登録日 | 2021-08-06 | | 公開日 | 2022-01-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol.
Nat.Struct.Mol.Biol., 29, 2022
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2MT5
 | | Isolated Ring domain | | 分子名称: | Anaphase-promoting complex subunit 11, ZINC ION | | 著者 | Brown, N.G, Watson, E.R, Weissman, F, Royappa, G, Schulman, B, Jarvis, M, Vanderlinden, R, Frye, J.J, Qiao, R, Petzold, G, Peters, J, Stark, H. | | 登録日 | 2014-08-13 | | 公開日 | 2014-10-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mechanism of Polyubiquitination by Human Anaphase-Promoting Complex: RING Repurposing for Ubiquitin Chain Assembly.
Mol.Cell, 56, 2014
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2C60
 | | crystal structure of human mitogen-activated protein kinase kinase kinase 3 isoform 2 phox domain at 1.25 A resolution | | 分子名称: | CALCIUM ION, GLYCEROL, HUMAN MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 3 ISOFORM 2 | | 著者 | Debreczeni, J.E, Salah, E, Papagrigoriou, E, Burgess, N, von Delft, F, Gileadi, O, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Knapp, S. | | 登録日 | 2005-11-04 | | 公開日 | 2005-11-29 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Crystal Structure of Human Mitogen-Activated Protein Kinase Kinase Kinase 3 Isoform 2 Fox Domain at 1.25 A Resolution
To be Published
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3TAB
 | | 5-hydroxycytosine paired with dGMP in RB69 gp43 | | 分子名称: | DNA (5'-D(*CP*CP*(5OC)P*GP*GP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*CP*CP*G)-3'), DNA polymerase, ... | | 著者 | Zahn, K.E. | | 登録日 | 2011-08-03 | | 公開日 | 2011-11-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The miscoding potential of 5-hydroxycytosine arises due to template instability in the replicative polymerase active site.
Biochemistry, 50, 2011
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5SVK
 | | Crystal structure of the ATP-gated human P2X3 ion channel in the ATP-bound, open state | | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E. | | 登録日 | 2016-08-06 | | 公開日 | 2016-09-28 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.773 Å) | | 主引用文献 | X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
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2C3M
 | | Crystal Structure Of Pyruvate-Ferredoxin Oxidoreductase From Desulfovibrio africanus | | 分子名称: | CALCIUM ION, CHLORIDE ION, IRON/SULFUR CLUSTER, ... | | 著者 | Cavazza, C, Contreras-Martel, C, Pieulle, L, Chabriere, E, Hatchikian, E.C, Fontecilla-Camps, J.C. | | 登録日 | 2005-10-11 | | 公開日 | 2006-02-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Flexibility of Thiamine Diphosphate Revealed by Kinetic Crystallographic Studies of the Reaction of Pyruvate-Ferredoxin Oxidoreductase with Pyruvate.
Structure, 14, 2006
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6GFL
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1PR5
 | | Escherichia coli Purine Nucleoside Phosphorylase Complexed with 7-deazaadenosine and Phosphate/Sulfate | | 分子名称: | '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type | | 著者 | Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E. | | 登録日 | 2003-06-19 | | 公開日 | 2003-11-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
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6SD4
 | | Structure of the RBM3/collar region of the Salmonella flagella MS-ring protein FliF with 34-fold symmetry applied | | 分子名称: | Flagellar M-ring protein | | 著者 | Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M. | | 登録日 | 2019-07-26 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation.
Nat Microbiol, 5, 2020
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5V3D
 | | Crystal structure of fosfomycin resistance protein from Klebsiella pneumoniae with bound fosfomycin | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FOSFOMYCIN, ... | | 著者 | Klontz, E, Guenther, S, Silverstein, Z, Sundberg, E. | | 登録日 | 2017-03-07 | | 公開日 | 2017-08-30 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.539 Å) | | 主引用文献 | Structure and Dynamics of FosA-Mediated Fosfomycin Resistance in Klebsiella pneumoniae and Escherichia coli.
Antimicrob. Agents Chemother., 61, 2017
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5O98
 | | Binary complex of Catharanthus roseus Vitrosamine Synthase with NADP+ | | 分子名称: | Alcohol dehydrogenase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Stavrinides, A.K, Tatsis, E.C, Dang, T.T, Caputi, L, Stevenson, C.E.M, Lawson, D.M, Schneider, B, O'Connor, S.E. | | 登録日 | 2017-06-16 | | 公開日 | 2018-02-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Discovery of a Short-Chain Dehydrogenase from Catharanthus roseus that Produces a New Monoterpene Indole Alkaloid.
Chembiochem, 19, 2018
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5LVM
 | | Human PDK1 Kinase Domain in Complex with Adenine Bound to the ATP-Binding Site | | 分子名称: | 3-phosphoinositide-dependent protein kinase 1, ADENINE, DITHIANE DIOL | | 著者 | Schulze, J.O, Saladino, G, Busschots, K, Neimanis, S, Suess, E, Odadzic, D, Zeuzem, S, Hindie, V, Herbrand, A.K, Lisa, M.N, Alzari, P.M, Gervasio, F.L, Biondi, R.M. | | 登録日 | 2016-09-14 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | | 主引用文献 | Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase.
Cell Chem Biol, 23, 2016
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6SGA
 | | Body domain of the mt-SSU assemblosome from Trypanosoma brucei | | 分子名称: | 9S rRNA, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Saurer, M, Ramrath, D.J.F, Niemann, M, Calderaro, S, Prange, C, Mattei, S, Scaiola, A, Leitner, A, Bieri, P, Horn, E.K, Leibundgut, M, Boehringer, D, Schneider, A, Ban, N. | | 登録日 | 2019-08-03 | | 公開日 | 2019-09-18 | | 最終更新日 | 2019-09-25 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
Science, 365, 2019
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6GOO
 | | Crystal Structure Of Sea Bream Transthyretin in complex with Perfluorooctanoic acid (PFOA). Crystallized in AmSO4 | | 分子名称: | Transthyretin, pentadecafluorooctanoic acid | | 著者 | Grundstrom, C, Zhang, J, Olofsson, A, Andersson, P.L, Sauer-Eriksson, A.E. | | 登録日 | 2018-06-01 | | 公開日 | 2018-07-11 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals.
Environ. Sci. Technol., 52, 2018
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6C5C
 | | Crystal structure of the 3-dehydroquinate synthase (DHQS) domain of Aro1 from Candida albicans SC5314 in complex with NADH | | 分子名称: | 1,2-ETHANEDIOL, 3-dehydroquinate synthase, CHLORIDE ION, ... | | 著者 | Michalska, K, Evdokimova, E, Di Leo, R, Stogios, P.J, Savchenko, A, Joachimiak, A, Satchell, K, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2018-01-16 | | 公開日 | 2018-01-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans.
Life Sci Alliance, 5, 2022
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1PTZ
 | | Crystal structure of the human CU, Zn Superoxide Dismutase, Familial Amyotrophic Lateral Sclerosis (FALS) Mutant H43R | | 分子名称: | COPPER (I) ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ... | | 著者 | DiDonato, M, Craig, L, Huff, M.E, Thayer, M.M, Cardoso, R.M.F, Kassmann, C.J, Lo, T.P, Bruns, C.K, Powers, E.T, Kelly, J.W, Getzoff, E.D, Tainer, J.A. | | 登録日 | 2003-06-23 | | 公開日 | 2003-09-09 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | ALS Mutants of Human Superoxide Dismutase Form Fibrous Aggregates Via Framework Destabilization
J.Mol.Biol., 332, 2003
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4ZCE
 | | Crystal Structure of the dust mite allergen Der p 23 from Dermatophagoides pteronyssinus | | 分子名称: | 1,2-ETHANEDIOL, Dust mite allergen | | 著者 | Pedersen, L.C, Mueller, G.A, Randall, T.A, Glesner, J, Perera, L, Edwards, L.L, Chapman, M.D, London, R.E, Pomes, A. | | 登録日 | 2015-04-15 | | 公開日 | 2015-11-25 | | 最終更新日 | 2019-12-11 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Serological, genomic and structural analyses of the major mite allergen Der p 23.
Clin Exp Allergy, 46, 2016
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1NZB
 | | Crystal structure of wild type Cre recombinase-loxP synapse | | 分子名称: | Cre recombinase, IODIDE ION, MAGNESIUM ION, ... | | 著者 | Ennifar, E, Meyer, J.E.W, Buchholz, F, Stewart, A.F, Suck, D. | | 登録日 | 2003-02-17 | | 公開日 | 2003-09-16 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal structure of a wild-type Cre recombinase-loxP synapse reveals a novel spacer conformation suggesting an alternative mechanism for DNA cleavage activation
Nucleic Acids Res., 31, 2003
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6H3B
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1HQH
 | | CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH NOR-N-HYDROXY-L-ARGININE | | 分子名称: | ARGINASE 1, MANGANESE (II) ION, NOR-N-OMEGA-HYDROXY-L-ARGININE | | 著者 | Cox, J.D, Cama, E, Colleluori, D.M, Ash, D.E, Christianson, D.W. | | 登録日 | 2000-12-16 | | 公開日 | 2001-04-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase.
Biochemistry, 40, 2001
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6PYH
 | | Cryo-EM structure of full-length IGF1R-IGF1 complex. Only the extracellular region of the complex is resolved. | | 分子名称: | Insulin-like growth factor 1 receptor, Insulin-like growth factor I | | 著者 | Li, J, Choi, E, Yu, H.T, Bai, X.C. | | 登録日 | 2019-07-29 | | 公開日 | 2019-10-23 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural basis of the activation of type 1 insulin-like growth factor receptor.
Nat Commun, 10, 2019
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