6PYH

Cryo-EM structure of full-length IGF1R-IGF1 complex. Only the extracellular region of the complex is resolved.

Summary for 6PYH

• Entry DOI: 10.2210/pdb6pyh/pdb
• EMDB information: 20524
• Descriptor: Insulin-like growth factor 1 receptor, Insulin-like growth factor I (2 entities in total)
• Functional Keywords: igf1r, igf1, signaling protein-hormone complex, signaling protein/hormone
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 3
• Total formula weight: 298223.56

Authors

Li, J.,Choi, E.,Yu, H.T.,Bai, X.C. (deposition date: 2019-07-29, release date: 2019-10-23)

• Primary citation: Li, J.,Choi, E.,Yu, H.,Bai, X.C.; Structural basis of the activation of type 1 insulin-like growth factor receptor.; Nat Commun, 10:4567-4567, 2019; PubMed: 31594955; DOI: 10.1038/s41467-019-12564-0

Experimental method

ELECTRON MICROSCOPY (4.3 Å)