6V3Z
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2TMN
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![BU of 2tmn by Molmil](/molmil-images/mine/2tmn) | CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN | 分子名称: | CALCIUM ION, N~2~-phosphono-L-leucinamide, Thermolysin, ... | 著者 | Tronrud, D.E, Monzingo, A.F, Matthews, B.W. | 登録日 | 1987-06-29 | 公開日 | 1989-01-09 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin. Eur.J.Biochem., 157, 1986
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7JYD
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![BU of 7jyd by Molmil](/molmil-images/mine/7jyd) | Human Liver Receptor Homolog-1 in Complex with 10CA and a Fragment of Tif2 | 分子名称: | 10-[(3aR,6R,6aR)-6-hydroxy-3-phenyl-3a-(1-phenylethenyl)-1,3a,4,5,6,6a-hexahydropentalen-2-yl]decanoic acid, Nuclear receptor coactivator 2, Nuclear receptor subfamily 5 group A member 2 | 著者 | D'Agostino, E.H, Mays, S.G, Ortlund, E.A. | 登録日 | 2020-08-30 | 公開日 | 2022-03-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Tapping into a phospholipid-LRH-1 axis yields a powerful anti-inflammatory agent with in vivo activity against colitis To Be Published
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2JH2
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![BU of 2jh2 by Molmil](/molmil-images/mine/2jh2) | X-ray crystal structure of a cohesin-like module from Clostridium perfringens | 分子名称: | O-GLCNACASE NAGJ | 著者 | Chitayat, S, Gregg, K, Adams, J.J, Ficko-Blean, E, Bayer, E.A, Boraston, A.B, Smith, S.P. | 登録日 | 2007-02-19 | 公開日 | 2007-11-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Three-Dimensional Structure of a Putative Non- Cellulosomal Cohesin Module from a Clostridium Perfringens Family 84 Glycoside Hydrolase. J.Mol.Biol., 375, 2008
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7AQ9
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![BU of 7aq9 by Molmil](/molmil-images/mine/7aq9) | Pseudomonas stutzeri nitrous oxide reductase mutant, H583W | 分子名称: | (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | 著者 | Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O. | 登録日 | 2020-10-20 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.585 Å) | 主引用文献 | Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase. J.Am.Chem.Soc., 143, 2021
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1OIY
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![BU of 1oiy by Molmil](/molmil-images/mine/1oiy) | Structure of human Thr160-phospho CDK2/cyclin A complexed with a 6-cyclohexylmethyloxy-2-anilino-purine inhibitor | 分子名称: | 4-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)--BENZAMIDE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, ... | 著者 | Pratt, D.J, Endicott, J.A, Noble, M.E.M. | 登録日 | 2003-06-26 | 公開日 | 2004-07-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | N2-Substituted O6-Cyclohexylmethylguanine Derivatives: Potent Inhibitors of Cyclin-Dependent Kinases 1 and 2 J.Med.Chem., 47, 2004
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7AQ2
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![BU of 7aq2 by Molmil](/molmil-images/mine/7aq2) | Pseudomonas stutzeri nitrous oxide reductase mutant, H583A | 分子名称: | (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | 著者 | Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O. | 登録日 | 2020-10-20 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.683 Å) | 主引用文献 | Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase. J.Am.Chem.Soc., 143, 2021
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2JLD
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![BU of 2jld by Molmil](/molmil-images/mine/2jld) | Extremely Tight Binding of Ruthenium Complex to Glycogen Synthase Kinase 3 | 分子名称: | GLYCOGEN SYNTHASE KINASE-3 BETA, PEPTIDE (ALA-GLY-GLY-ALA-ALA-ALA-ALA-ALA), RUTHENIUM PYRIDOCARBAZOLE | 著者 | Atilla-Gokcumen, G.E, Pagano, N, Streu, C, Maksimoska, J, Filippakopoulos, P, Knapp, S, Meggers, E. | 登録日 | 2008-09-08 | 公開日 | 2008-12-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Extremely Tight Binding of a Ruthenium Complex to Glycogen Synthase Kinase 3. Chembiochem, 9, 2008
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5IK4
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![BU of 5ik4 by Molmil](/molmil-images/mine/5ik4) | Laminin A2LG45 C-form, Apo. | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Briggs, D.C, Hohenester, E, Campbell, K.P. | 登録日 | 2016-03-03 | 公開日 | 2016-08-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | 主引用文献 | Structural basis of laminin binding to the LARGE glycans on dystroglycan. Nat.Chem.Biol., 12, 2016
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5Y7J
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![BU of 5y7j by Molmil](/molmil-images/mine/5y7j) | Crystal structure of human DPP4 in complex with inhibitor2 | 分子名称: | (S)-4-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(tert-butoxymethyl)piperazin-2-one, Dipeptidyl peptidase 4 | 著者 | Lee, H.K, Kim, E.E. | 登録日 | 2017-08-17 | 公開日 | 2019-03-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.521 Å) | 主引用文献 | Unique binding mode of Evogliptin with human dipeptidyl peptidase IV. Biochem.Biophys.Res.Commun., 494, 2017
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1IGP
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1OI9
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![BU of 1oi9 by Molmil](/molmil-images/mine/1oi9) | Structure of human Thr160-phospho CDK2/cyclin A complexed with a 6-cyclohexylmethyloxy-2-anilino-purine inhibitor | 分子名称: | 6-CYCLOHEXYLMETHYLOXY-2-(4'-HYDROXYANILINO)PURINE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, ... | 著者 | Pratt, D.J, Endicott, J.A, Noble, M.E.M. | 登録日 | 2003-06-10 | 公開日 | 2004-07-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | N2-Substituted O6-Cyclohexylmethylguanine Derivatives: Potent Inhibitors of Cyclin-Dependent Kinases 1 and 2 J.Med.Chem., 47, 2004
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6S2I
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4MCF
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![BU of 4mcf by Molmil](/molmil-images/mine/4mcf) | Crystal structure of the Gas5 GRE Mimic | 分子名称: | Gas5 GREM Fwd, Gas5 GREM Rev, SULFATE ION | 著者 | Hudson, W.H, Ortlund, E.A. | 登録日 | 2013-08-21 | 公開日 | 2014-11-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | 主引用文献 | Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate. Nat Commun, 5, 2014
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5Y5L
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![BU of 5y5l by Molmil](/molmil-images/mine/5y5l) | Time-resolved SFX structure of cytochrome P450nor: dark-2 data in the absence of NADH (resting state) | 分子名称: | NADP nitrous oxide-forming nitric oxide reductase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Tosha, T, Nomura, T, Nishida, T, Saeki, N, Okubayashi, K, Yamagiwa, R, Sugahara, M, Nakane, T, Yamashita, K, Hirata, K, Ueno, G, Kimura, T, Hisano, T, Muramoto, K, Sawai, H, Takeda, H, Mizohata, E, Yamashita, A, Kanematsu, Y, Takano, Y, Nango, E, Tanaka, R, Nureki, O, Ikemoto, Y, Murakami, H, Owada, S, Tono, K, Yabashi, M, Yamamoto, M, Ago, H, Iwata, S, Sugimoto, H, Shiro, Y, Kubo, M. | 登録日 | 2017-08-09 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate. Nat Commun, 8, 2017
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5SVR
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![BU of 5svr by Molmil](/molmil-images/mine/5svr) | Crystal structure of the ATP-gated human P2X3 ion channel bound to competitive antagonist A-317491 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-{[(3-phenoxyphenyl)methyl][(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl}benzene-1,2,4-tricarboxylic acid, MAGNESIUM ION, ... | 著者 | Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E. | 登録日 | 2016-08-07 | 公開日 | 2016-10-05 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | 主引用文献 | X-ray structures define human P2X3 receptor gating cycle and antagonist action. Nature, 538, 2016
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6M8W
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![BU of 6m8w by Molmil](/molmil-images/mine/6m8w) | PSEUDOMONAS SERINE-CARBOXYL PROTEINASE (SEDOLISIN) COMPLEXED WITH THE INHIBITOR AIAF | 分子名称: | AIAF PEPTIDE INHIBITOR, CALCIUM ION, CHLORIDE ION, ... | 著者 | Wlodawer, A, Li, M, Gustchina, A, Dauter, Z, Uchida, K, Oyama, H, Goldfarb, N.E, Dunn, B.M, Oda, K. | 登録日 | 2018-08-22 | 公開日 | 2018-10-24 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Inhibitor complexes of the Pseudomonas serine-carboxyl proteinase Biochemistry, 40, 2001
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1J9J
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![BU of 1j9j by Molmil](/molmil-images/mine/1j9j) | CRYSTAL STRUCTURE ANALYSIS OF SURE PROTEIN FROM T.MARITIMA | 分子名称: | MAGNESIUM ION, STATIONARY PHASE SURVIVAL PROTEIN, SULFATE ION | 著者 | Suh, S.W, Lee, J.Y, Kwak, J.E, Moon, J. | 登録日 | 2001-05-27 | 公開日 | 2001-09-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure and functional analysis of the SurE protein identify a novel phosphatase family. Nat.Struct.Biol., 8, 2001
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1OIU
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![BU of 1oiu by Molmil](/molmil-images/mine/1oiu) | Structure of human Thr160-phospho CDK2/cyclin A complexed with a 6-cyclohexylmethyloxy-2-anilino-purine inhibitor | 分子名称: | 3-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)-BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, ... | 著者 | Pratt, D.J, Endicott, J.A, Noble, M.E.M. | 登録日 | 2003-06-26 | 公開日 | 2004-07-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | N2-Substituted O6-Cyclohexylmethylguanine Derivatives: Potent Inhibitors of Cyclin-Dependent Kinases 1 and 2 J.Med.Chem., 47, 2004
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6VEN
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2K4F
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![BU of 2k4f by Molmil](/molmil-images/mine/2k4f) | Mouse CD3epsilon Cytoplasmic Tail | 分子名称: | T-cell surface glycoprotein CD3 epsilon chain | 著者 | Xu, C, Call, M.E, Schwieters, C.D, Schnell, J.R, Gagnon, E.E, Wucherpfennig, K.W, Chou, J.J. | 登録日 | 2008-06-07 | 公開日 | 2008-12-02 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3varepsilon Cytoplasmic Tyrosine-Based Motif. Cell(Cambridge,Mass.), 135, 2008
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5TFT
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![BU of 5tft by Molmil](/molmil-images/mine/5tft) | Structure of cytochrome P450 2D6 (CYP2D6) BACE1 inhibitor complex | 分子名称: | (4S)-4-[2,4-difluoro-5-({[1-(trifluoromethyl)cyclopropyl]amino}methyl)phenyl]-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine, Cytochrome P450 2D6, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Hsu, M.H, Johnson, E.F. | 登録日 | 2016-09-26 | 公開日 | 2017-01-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality. J. Med. Chem., 60, 2017
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6SBN
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![BU of 6sbn by Molmil](/molmil-images/mine/6sbn) | Polyester hydrolase PE-H of Pseudomonas aestusnigri | 分子名称: | ACETATE ION, SODIUM ION, polyester hydrolase | 著者 | Bollinger, A, Thies, S, Kobus, S, Hoeppner, A, Smits, S.H.J, Jaeger, K.-E. | 登録日 | 2019-07-22 | 公開日 | 2020-02-26 | 最終更新日 | 2020-03-11 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | A Novel Polyester Hydrolase From the Marine BacteriumPseudomonas aestusnigri -Structural and Functional Insights. Front Microbiol, 11, 2020
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6SCN
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![BU of 6scn by Molmil](/molmil-images/mine/6scn) | 33mer structure of the Salmonella flagella MS-ring protein FliF | 分子名称: | Flagellar M-ring protein | 著者 | Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M. | 登録日 | 2019-07-24 | 公開日 | 2020-03-18 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation. Nat Microbiol, 5, 2020
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5YAK
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