1MOO
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![BU of 1moo by Molmil](/molmil-images/mine/1moo) | Site Specific Mutant (H64A) of Human Carbonic Anhydrase II at high resolution | Descriptor: | 4-METHYLIMIDAZOLE, Carbonic Anhydrase II, MERCURY (II) ION, ... | Authors: | Duda, D.M, Govindasamy, L, Agbandje-McKenna, M, Tu, C.K, Silverman, D.N, McKenna, R. | Deposit date: | 2002-09-09 | Release date: | 2002-09-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | The refined atomic structure of carbonic anhydrase II at 1.05 A resolution: implications of chemical rescue of proton transfer. Acta Crystallogr.,Sect.D, 59, 2003
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8CAF
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![BU of 8caf by Molmil](/molmil-images/mine/8caf) | N8C_Fab3b in complex with NEDD8-CUL1(WHB) | Descriptor: | Cullin-1, Fab Heavy Chain, Fab Light Chain, ... | Authors: | Duda, D.M, Yanishevski, D, Henneberg, L.T, Schulman, B.A. | Deposit date: | 2023-01-24 | Release date: | 2023-09-13 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | Activity-based profiling of cullin-RING E3 networks by conformation-specific probes. Nat.Chem.Biol., 19, 2023
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4KBL
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![BU of 4kbl by Molmil](/molmil-images/mine/4kbl) | Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism | Descriptor: | E3 ubiquitin-protein ligase ARIH1, ZINC ION | Authors: | Duda, D.M, Olszewski, J.L, Schulman, B.A. | Deposit date: | 2013-04-23 | Release date: | 2013-05-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism. Structure, 21, 2013
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4KC9
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![BU of 4kc9 by Molmil](/molmil-images/mine/4kc9) | Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism | Descriptor: | E3 ubiquitin-protein ligase ARIH1, ZINC ION | Authors: | Duda, D.M, Olszewski, J.L, Schulman, B.A. | Deposit date: | 2013-04-24 | Release date: | 2013-05-29 | Last modified: | 2013-07-03 | Method: | X-RAY DIFFRACTION (3.603 Å) | Cite: | Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism. Structure, 21, 2013
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2EKE
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![BU of 2eke by Molmil](/molmil-images/mine/2eke) | |
4F52
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![BU of 4f52 by Molmil](/molmil-images/mine/4f52) | Structure of a Glomulin-RBX1-CUL1 complex | Descriptor: | Cullin-1, E3 ubiquitin-protein ligase RBX1, Glomulin, ... | Authors: | Duda, D.M, Olszewski, J.L, Schulman, B.A. | Deposit date: | 2012-05-11 | Release date: | 2012-09-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface. Mol.Cell, 47, 2012
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3DQV
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![BU of 3dqv by Molmil](/molmil-images/mine/3dqv) | Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation | Descriptor: | Cullin-5, NEDD8, Rbx1, ... | Authors: | Duda, D.M, Borg, L.A, Scott, D.C, Hunt, H.W, Hammel, M, Schulman, B.A. | Deposit date: | 2008-07-09 | Release date: | 2008-09-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation. Cell(Cambridge,Mass.), 134, 2008
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3DPL
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![BU of 3dpl by Molmil](/molmil-images/mine/3dpl) | |
1Z97
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![BU of 1z97 by Molmil](/molmil-images/mine/1z97) | Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer. | Descriptor: | Carbonic anhydrase III, ZINC ION | Authors: | Duda, D.M, Tu, C, Fisher, S.Z, An, H, Yoshioka, C, Govindasamy, L, Laipis, P.J, Agbandje-McKenna, M, Silverman, D.N, McKenna, R. | Deposit date: | 2005-03-31 | Release date: | 2005-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer Biochemistry, 44, 2005
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1ZKM
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![BU of 1zkm by Molmil](/molmil-images/mine/1zkm) | Structural Analysis of Escherichia Coli ThiF | Descriptor: | Adenylyltransferase thiF, ZINC ION | Authors: | Duda, D.M, Walden, H, Sfondouris, J, Schulman, B.A. | Deposit date: | 2005-05-03 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural Analysis of Escherichia Coli ThiF. J.Mol.Biol., 349, 2005
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1ZFN
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![BU of 1zfn by Molmil](/molmil-images/mine/1zfn) | Structural Analysis of Escherichia coli ThiF | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Adenylyltransferase thiF, ZINC ION | Authors: | Duda, D.M, Walden, H, Sfondouris, J, Schulman, B.A. | Deposit date: | 2005-04-20 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural Analysis of Escherichia Coli ThiF. J.Mol.Biol., 349, 2005
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1Z93
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![BU of 1z93 by Molmil](/molmil-images/mine/1z93) | Human Carbonic Anhydrase III:Structural and Kinetic study of Catalysis and Proton Transfer. | Descriptor: | Carbonic anhydrase III, ZINC ION | Authors: | Duda, D.M, Tu, C, Fisher, S.Z, An, H, Yoshioka, C, Govindasamy, L, Laipis, P.J, Agbandje-McKenna, M, Silverman, D.N, McKenna, R. | Deposit date: | 2005-03-31 | Release date: | 2005-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer Biochemistry, 44, 2005
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3RTR
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![BU of 3rtr by Molmil](/molmil-images/mine/3rtr) | A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases | Descriptor: | Cullin-1, E3 ubiquitin-protein ligase RBX1, ZINC ION | Authors: | Calabrese, M.F, Scott, D.C, Duda, D.M, Grace, C.R, Kurinov, I, Kriwacki, R.W, Schulman, B.A. | Deposit date: | 2011-05-03 | Release date: | 2011-07-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases. Nat.Struct.Mol.Biol., 18, 2011
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3O2U
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![BU of 3o2u by Molmil](/molmil-images/mine/3o2u) | S. cerevisiae Ubc12 | Descriptor: | GLYCEROL, NEDD8-conjugating enzyme UBC12 | Authors: | Scott, D.C, Monda, J.K, Grace, C.R.R, Duda, D.M, Kriwacki, R.W, Kurz, T, Schulman, B.A. | Deposit date: | 2010-07-22 | Release date: | 2010-09-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | A dual E3 mechanism for Rub1 ligation to Cdc53. Mol.Cell, 39, 2010
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3O2P
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![BU of 3o2p by Molmil](/molmil-images/mine/3o2p) | A Dual E3 Mechanism for Rub1 Ligation to Cdc53: Dcn1(P)-Cdc53(WHB) | Descriptor: | Cell division control protein 53, Defective in cullin neddylation protein 1, GLYCEROL | Authors: | Scott, D.C, Monda, J.K, Grace, C.R.R, Duda, D.M, Kriwacki, R.W, Kurz, T, Schulman, B.A. | Deposit date: | 2010-07-22 | Release date: | 2010-09-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.233 Å) | Cite: | A dual E3 mechanism for Rub1 ligation to Cdc53. Mol.Cell, 39, 2010
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4GSL
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![BU of 4gsl by Molmil](/molmil-images/mine/4gsl) | Crystal structure of an Atg7-Atg3 crosslinked complex | Descriptor: | Autophagy-related protein 3, Ubiquitin-like modifier-activating enzyme ATG7, ZINC ION | Authors: | Kaiser, S.E, Mao, K, Taherbhoy, A.M, Yu, S, Olszewski, J.L, Duda, D.M, Kurinov, I, Deng, A, Fenn, T.D, Klionsky, D.J, Schulman, B.A. | Deposit date: | 2012-08-27 | Release date: | 2012-11-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.703 Å) | Cite: | Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures. Nat.Struct.Mol.Biol., 19, 2012
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4GSJ
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![BU of 4gsj by Molmil](/molmil-images/mine/4gsj) | Crystal structure of Atg7 NTD K14A F16A D18A mutant | Descriptor: | CITRIC ACID, ISOPROPYL ALCOHOL, Ubiquitin-like modifier-activating enzyme ATG7 | Authors: | Kaiser, S.E, Mao, K, Taherbhoy, A.M, Yu, S, Olszewski, J.L, Duda, D.M, Kurinov, I, Deng, A, Fenn, T.D, Klionsky, D.J, Schulman, B.A. | Deposit date: | 2012-08-27 | Release date: | 2012-11-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.695 Å) | Cite: | Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures. Nat.Struct.Mol.Biol., 19, 2012
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4GSK
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![BU of 4gsk by Molmil](/molmil-images/mine/4gsk) | Crystal structure of an Atg7-Atg10 crosslinked complex | Descriptor: | Ubiquitin-like modifier-activating enzyme ATG7, Ubiquitin-like-conjugating enzyme ATG10, ZINC ION | Authors: | Kaiser, S.E, Mao, K, Taherbhoy, A.M, Yu, S, Olszewski, J.L, Duda, D.M, Kurinov, I, Deng, A, Fenn, T.D, Klionsky, D.J, Schulman, B.A. | Deposit date: | 2012-08-27 | Release date: | 2012-11-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures. Nat.Struct.Mol.Biol., 19, 2012
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3O6B
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![BU of 3o6b by Molmil](/molmil-images/mine/3o6b) | A Dual E3 Mechanism for Rub1 Ligation to Cdc53: Dcn1(P)-Cdc53(WHB) low resolution | Descriptor: | Cell division control protein 53, Defective in cullin neddylation protein 1 | Authors: | Scott, D.C, Monda, J.K, Grace, C.R.R, Duda, D.M, Kriwacki, R.W, Kurz, T, Schulman, B.A. | Deposit date: | 2010-07-28 | Release date: | 2010-09-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | A dual E3 mechanism for Rub1 ligation to Cdc53. Mol.Cell, 39, 2010
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1LZV
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![BU of 1lzv by Molmil](/molmil-images/mine/1lzv) | Site-Specific Mutant (Tyr7 replaced with His) of Human Carbonic Anhydrase II | Descriptor: | Carbonic Anhydrase II, ZINC ION | Authors: | Tu, C.K, Qian, M, An, H, Wadhwa, N.R, Duda, D.M, Yoshioka, C, Pathak, Y, McKenna, R, Laipis, P.J, Silverman, D.N. | Deposit date: | 2002-06-11 | Release date: | 2002-10-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Kinetic analysis of multiple proton shuttles in the active site of human carbonic anhydrase. J.Biol.Chem., 277, 2002
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3FN1
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![BU of 3fn1 by Molmil](/molmil-images/mine/3fn1) | E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification. | Descriptor: | NEDD8-activating enzyme E1 catalytic subunit, NEDD8-conjugating enzyme UBE2F | Authors: | Huang, D.T, Ayrault, O, Hunt, H.W, Taherbhoy, A.M, Duda, D.M, Scott, D.C, Borg, L.A, Neale, G, Murray, P.J, Roussel, M.F, Schulman, B.A. | Deposit date: | 2008-12-22 | Release date: | 2009-03-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification Mol.Cell, 33, 2009
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2GJD
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![BU of 2gjd by Molmil](/molmil-images/mine/2gjd) | Distinct functional domains of Ubc9 dictate cell survival and resistance to genotoxic stress | Descriptor: | Ubiquitin-conjugating enzyme E2-18 kDa | Authors: | van Waardenburg, R.C, Duda, D.M, Lancaster, C.S, Schulman, B.A, Bjornsti, M.A. | Deposit date: | 2006-03-30 | Release date: | 2006-07-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Distinct functional domains of ubc9 dictate cell survival and resistance to genotoxic stress. Mol.Cell.Biol., 26, 2006
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