3FN1

E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.

Summary for 3FN1

DescriptorNEDD8-activating enzyme E1 catalytic subunit, NEDD8-conjugating enzyme UBE2F (3 entities in total)
Functional Keywordsligase, atp-binding, cell cycle, nucleotide-binding, ubl conjugation pathway
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight29961.57
Authors
Huang, D.T.,Ayrault, O.,Hunt, H.W.,Taherbhoy, A.M.,Duda, D.M.,Scott, D.C.,Borg, L.A.,Neale, G.,Murray, P.J.,Roussel, M.F.,Schulman, B.A. (deposition date: 2008-12-22, release date: 2009-03-17, Last modification date: 2018-01-24)
Primary citation
Huang, D.T.,Ayrault, O.,Hunt, H.W.,Taherbhoy, A.M.,Duda, D.M.,Scott, D.C.,Borg, L.A.,Neale, G.,Murray, P.J.,Roussel, M.F.,Schulman, B.A.
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
Mol.Cell, 33:483-495, 2009
PubMed: 19250909 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2009.01.011
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25680.4%5.9%8.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3fn1
no rotation
Molmil generated image of 3fn1
rotated about x axis by 90°
Molmil generated image of 3fn1
rotated about y axis by 90°